Inflammation And Fibrosis In The Gastrointestinal Tract And Liver Mechanisms And Targets
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Inflammation And Fibrosis In The Gastrointestinal Tract And Liver Mechanisms And Targets
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Author : Ralf Weiskirchen
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-04
Inflammation And Fibrosis In The Gastrointestinal Tract And Liver Mechanisms And Targets written by Ralf Weiskirchen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-04 with Science categories.
Mechanisms Of Chronic Liver Diseases Identifying New Therapeutic Targets
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Author : Gianfranco Danilo Alpini
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-25
Mechanisms Of Chronic Liver Diseases Identifying New Therapeutic Targets written by Gianfranco Danilo Alpini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-25 with Medical categories.
Hepatic Fibrosis
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Author : Pablo Muriel
language : en
Publisher: Academic Press
Release Date : 2022-04-23
Hepatic Fibrosis written by Pablo Muriel and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-23 with Science categories.
Hepatic Fibrosis: Mechanisms and Targets is a complete volume of liver extracellular matrix biology, including molecular signaling pathways, cells and factors that modulate fibrogenesis and fibrosis. The book uses an integrated approach toward the molecular and cellular mechanisms involved in the synthesis and degradation of hepatic fibrotic tissue, emphasizing the possible molecular targets to fight fibrosis. This important reference describes, in detail and didactically, the cellular and molecular events that are conducive to fibrosis that leads to cirrhosis, hepatocellular carcinoma and death. The provided information allows readers to understand the molecular mechanisms of hepatic fibrogenesis to accelerate the development of new therapies. Presents progression from inflammation to fibrosis, with a special focus on the molecular mechanisms involved Didactically explains the participation of cells, cytokines and factors in profibrogenic pathways Illuminates the causative participation of free radicals in liver fibrogenesis Explains the role of gut dysbiosis in chronic liver diseases leading to fibrosis Provides experimental models to study liver fibrosis and describes available, noninvasive monitoring methods
Inflammatory Immune Disease Molecular Mechanisms Translational Approaches And Therapeutics Volume Ii
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Author : Tao Xu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-17
Inflammatory Immune Disease Molecular Mechanisms Translational Approaches And Therapeutics Volume Ii written by Tao Xu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-17 with Science categories.
Advances In Non Alcoholic Fatty Liver Disease Therapeutics Pathogenic Mechanisms And Targets
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Author : Ana Blas-García
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-05
Advances In Non Alcoholic Fatty Liver Disease Therapeutics Pathogenic Mechanisms And Targets written by Ana Blas-García and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-05 with Science categories.
Clinical Update On Inflammatory Disorders Of The Gastrointestinal Tract
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Author : Julia Mayerle
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2010
Clinical Update On Inflammatory Disorders Of The Gastrointestinal Tract written by Julia Mayerle and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Science categories.
Digestive-disease-associated mortality accounts for a major part of all deaths in Western societies and inflammatory diseases such as GI infections, viral hepatitis, GERD or cancers due to chronic inflammation have a tangible economic and social impact. What further aggravates the situation is the fact that complex immunological disorders have surfaced where anti-infective treatments are not effective. Fortunately, due to breakthroughs in basic research that are being successfully translated into clinical practice, new treatment strategies are constantly evolving. In addition to the development of new therapeutic measures, however, it is also mandatory to review and periodically refine established treatment regimens to reflect current knowledge and ensure up-to-date medical care.Combining outstanding basic research reviews with cutting-edge treatment guidelines on inflammatory disorders of the GI tract, this book presents newly identified treatment targets and provides clinicians and practitioners in the field with a most useful account of the state of the art.
Cooperation Of Liver Cells In Health And Disease
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Author : Z. Kmiec
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Cooperation Of Liver Cells In Health And Disease written by Z. Kmiec and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.
Pathogenetic Mechanism And Therapeutic Target For Inflammation In Autoimmune Disease
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Author : Jing Tian
language : en
Publisher: Frontiers Media SA
Release Date : 2024-03-13
Pathogenetic Mechanism And Therapeutic Target For Inflammation In Autoimmune Disease written by Jing Tian and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-13 with Medical categories.
Cellular And Molecular Mechanisms Underlying The Pathogenesis Of Hepatic Fibrosis
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Author : Ralf Weiskirchen
language : en
Publisher:
Release Date : 2020
Cellular And Molecular Mechanisms Underlying The Pathogenesis Of Hepatic Fibrosis written by Ralf Weiskirchen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Worldwide, liver fibrosis is a major cause of morbidity and mortality and is associated with a high medical and economic burden. It is the common consequence of chronic liver injury due to various etiologies. During fibrogenesis, there is a progressive substitution of the liver parenchyma by scar tissue. Recent advances in the understanding of the history of liver fibrosis have shown that the pathogenesis is driven by different cell types and a large variety of soluble mediators. At present, scientists working in this field aim to increase basic knowledge, improve diagnostics, and try to translate experimental findings into new treatment modalities. This book includes 12 selected contributions from the Special Issue “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis” that was published in Cells. These articles summarize current perspectives and findings in hepatic fibrosis research showing how scientists try to use basic scientific research to create new therapies and diagnostics.
Stellate Cells In Health And Disease
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Author : Chandrashekhar Gandhi
language : en
Publisher: Academic Press
Release Date : 2015-04-10
Stellate Cells In Health And Disease written by Chandrashekhar Gandhi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-10 with Science categories.
Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology. Presents coverage of the mechanisms of liver fibrosis with stellate cells as a target for therapy. Shows stellate cells as a major participant in hepatic immunobiology, including transplantation immunology. Key illustrations show the phenotypical changes in stellate cells in situ and tissue culture, their interactions with other cell types, signaling pathways and demonstrate the functions and roles of stellate cell in pathological processes.