Inflammation In Psychiatry
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Inflammation In Psychiatry
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Author : A. Halaris
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2013-02-27
Inflammation In Psychiatry written by A. Halaris and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-27 with Medical categories.
Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co-morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlying the bidirectionality of co-morbid medical and psychiatric disorders can be viewed as a consequence of inflammatory changes. These emerging novel concepts illustrate how the knowledge of inflammation can enable meaningful integration of psychopathology with physical co-morbidity. The innovative articles in this volume highlight the intricate link between psychiatry and psychoimmunology and underscore the central role of inflammation in furthering our understanding of the pathophysiology underlying mental health and illness.
The Role Of Inflammation In The Etiology And Treatment Of Schizophrenia
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Author : Ole Köhler-Forsberg
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-23
The Role Of Inflammation In The Etiology And Treatment Of Schizophrenia written by Ole Köhler-Forsberg and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-23 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Inflammation Associated Depression Evidence Mechanisms And Implications
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Author : Robert Dantzer
language : en
Publisher: Springer
Release Date : 2016-12-28
Inflammation Associated Depression Evidence Mechanisms And Implications written by Robert Dantzer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-28 with Medical categories.
Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.
Peripheral Markers Of Immune Response In Major Psychiatric Disorders Where Are We Now And Where Do We Want To Be
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Author : Błażej Misiak
language : en
Publisher: Frontiers Media SA
Release Date : 2019-04-03
Peripheral Markers Of Immune Response In Major Psychiatric Disorders Where Are We Now And Where Do We Want To Be written by Błażej Misiak and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-03 with categories.
Major psychiatric disorders, including schizophrenia, bipolar disorder and major depression represent complex phenotypes with imprecise diagnostic boundaries. It has been found that these disorders can be characterized by a number of peripheral immune-inflammatory alterations, including, i.e. elevated levels of pro-inflammatory cytokines, increased levels of specific and non-specific antibodies or abnormal counts of lymphocyte subpopulations. Although it has been found that major psychiatric disorders share similar dysregulations of immune-inflammatory response, recent studies have also clearly demonstrated that some differences can be indicated. Interestingly, certain immune-inflammatory disturbances appear to be state markers, since they occur in acute relapse and normalize following pharmacological treatment, while the rest represents trait markers that remain stable regardless of treatment. It is also important to note that peripheral immune-inflammatory markers have been associated with psychopathological manifestation of major psychiatric disorders, response to treatment and long-term outcomes. However, it remains unclear what is the origin of peripheral inflammation in psychiatric disorders. To date, several mechanisms have been proposed, including the gut-brain axis dysregulation, infections in the neurodevelopmental period or immunogenetic factors. This eBook summarizes current evidence from studies investigating peripheral inflammation in schizophrenia, bipolar disorder, major depression and post-traumatic stress disorder as well as it provides future directions for the field.
Immuno Psychiatry
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Author : Michael Berk
language : en
Publisher: Springer Nature
Release Date : 2021-08-14
Immuno Psychiatry written by Michael Berk and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-14 with Medical categories.
This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the authors discuss the innovative immune-therapies that may result from the discovery of immune system biomarkers and their associated mechanisms. A better understanding of the role of the immune system in psychiatric disorders makes it possible to identify stratification biomarkers, to explain underlying mechanisms, and to develop innovative, efficient, targeted treatment strategies and management. As such, the book is of value to clinicians, mental health professionals, mental health researchers, immunologists, industry practitioners, and various stakeholders in the mental health field.
Perinatal Inflammation And Adult Psychopathology
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Author : Antonio L. Teixeira
language : en
Publisher: Springer Nature
Release Date : 2020-04-07
Perinatal Inflammation And Adult Psychopathology written by Antonio L. Teixeira and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-07 with Medical categories.
Perinatal psychiatry is an emerging field that investigates the role of perinatal events – for example pregnancy complications and infections – in the development of neuropsychiatric conditions, such as schizophrenia and mood disorders. Among the implicated pathological mechanisms, perinatal-induced inflammation seems to play a major role and is being considered as a potential target for therapeutic intervention. Bringing together various approaches in the field (preclinical and clinical, epidemiological, immunological and genetic methods), the book discusses the available evidence, the putative mechanisms and the challenges ahead.
Inflammation And Immunity In Depression
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Author : Bernhard Baune
language : en
Publisher: Academic Press
Release Date : 2018-05-23
Inflammation And Immunity In Depression written by Bernhard Baune and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-23 with Medical categories.
Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions
The Inflamed Mind
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Author : Edward Bullmore
language : en
Publisher: Hachette UK
Release Date : 2019-01-03
The Inflamed Mind written by Edward Bullmore and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-03 with Psychology categories.
Depression will be the single biggest cause of disability worldwide, in the next 20 years. But treatment for it has not changed much in the last three decades. In the realm of psychiatry, time has apparently stood still... until now.In this game-changing book, Professor Edward Bullmore reveals the breakthrough new science on the link between mental depression and physical inflammation. He explains how and why mental disorders can have their roots in the immune system and explores a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world.
Neuroinflammation And Schizophrenia
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Author : Golam M. Khandaker
language : en
Publisher: Springer Nature
Release Date : 2020-01-22
Neuroinflammation And Schizophrenia written by Golam M. Khandaker and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-22 with Medical categories.
This book provides a comprehensive summary of the cutting edge scientific evidence regarding the role of immune system in the pathogenesis and treatment of schizophrenia and related psychotic disorders. It illustrates the role of inflammation and immunity in schizophrenia drawing on both basic science and clinical research. The chapters provide up-to-date summaries of immunological risk factors for schizophrenia and related psychotic disorders, and underlying mechanisms as informed by neuroimaging, genetic, clinical and animal experimental studies. In addition, the book will illuminate the scope for immunological treatment for schizophrenia.
Textbook Of Immunopsychiatry
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Author : Golam Khandaker
language : en
Publisher: Cambridge University Press
Release Date : 2021-09-23
Textbook Of Immunopsychiatry written by Golam Khandaker and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-23 with Medical categories.
An essential book summarizing cutting-edge evidence on the role of the immune system and immunotherapies in psychiatric disorders.