Inhalation Drug Delivery
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Inhalation Drug Delivery
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Author : Paolo Colombo
language : en
Publisher: John Wiley & Sons
Release Date : 2013-02-11
Inhalation Drug Delivery written by Paolo Colombo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-11 with Science categories.
There has been a rapid evolution in the field of inhalation drug therapy, including new drugs, increased regulation and quality control, and strong pressure from generics. Inhalation Drug Therapy brings together the most current inhalation drug research, as well as practical developments and processes, into one essential guide. Focusing on inhalation products and specific equipment and techniques used in manufacturing and quality control, the book balances research with the industrial aspects of creating the drugs, and features a highly regarded author team with both academic and industry experience.
Pulmonary Drug Delivery
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Author : Ali Nokhodchi
language : en
Publisher: John Wiley & Sons
Release Date : 2015-08-03
Pulmonary Drug Delivery written by Ali Nokhodchi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-03 with Science categories.
Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.
Controlled Pulmonary Drug Delivery
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Author : Hugh D.C. Smyth
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-24
Controlled Pulmonary Drug Delivery written by Hugh D.C. Smyth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-24 with Medical categories.
The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.
Drug Delivery To The Respiratory Tract
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Author : David Ganderton
language : en
Publisher:
Release Date : 1987
Drug Delivery To The Respiratory Tract written by David Ganderton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
In treating diseases of the respiratory tract, the direct administration of drugs has great advantages in terms of clinical efficiency. This book reviews the most important recent developments in drug delivery systems to the respiratory tract. Starting with a detailed description of lung strucure and function, successive chapters investigate the usefulness of the pulmonary presention of beta-agonists, steroids and chromoglycate, and explain metabolic function and susceptibility to chemical damage from the environment, showing that the lung is far from being a passive organ. Further contributions demonstrate the importance of mucus in humidification, particle capture and particle removal before attention is given to the practical problems of drug delivery and the commercially viable devices available to the pharmaceutical technologist: the metered dose inhaler, the powder inhaler, and the jet nebuliser. The final chapter examines the future role of intranasal delivery systems, based upon the principles described.
Drug Delivery To The Lung
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Author : Hans Bisgaard
language : en
Publisher: CRC Press
Release Date : 2001-10-02
Drug Delivery To The Lung written by Hans Bisgaard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-02 with Medical categories.
This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract!Featuring over 1300 references, drawings, tables, and photographs.
Pharmaceutical Inhalation Aerosol Technology Second Edition
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Author : Anthony J. Hickey
language : en
Publisher: CRC Press
Release Date : 2003-09-03
Pharmaceutical Inhalation Aerosol Technology Second Edition written by Anthony J. Hickey and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-03 with Medical categories.
This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.
Advances In Pulmonary Drug Delivery
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Author : Philip Chi Lip Kwok
language : en
Publisher: CRC Press
Release Date : 2016-12-19
Advances In Pulmonary Drug Delivery written by Philip Chi Lip Kwok and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-19 with Medical categories.
The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and parenteral administration. Pulmonary drug development is therefore a highly specialized area because of its many unique issues and challenges. Rapid progress is being made and offers novel solutions to existing treatment problems. Advances in Pulmonary Drug Delivery highlights the latest developments in this field.
Respiratory Drug Delivery 1989
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Author : Peter R. Byron
language : en
Publisher: CRC Press
Release Date : 2018-04-20
Respiratory Drug Delivery 1989 written by Peter R. Byron and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-20 with Medical categories.
The focus of this book is on subjects related to drug delivery to the lung. The text spans topics from aerosol deposition through pharmaceutical chemistry and formulation to the final clinical evaluation of pharmaceutical products. Utilizing a multi-disciplinary approach, the chapters consider toxicology from the point of view of drugs and pharmaceutical excipients used in aerosols.
Inhaled Delivery Systems For The Treatment Of Asthma And Copd
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Author : Donald A. Mahler
language : en
Publisher: CRC Press
Release Date : 2023-07-19
Inhaled Delivery Systems For The Treatment Of Asthma And Copd written by Donald A. Mahler and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-19 with Medical categories.
Inhaled therapies form the cornerstone for treatment of patients with asthma and COPD. Evolving technology has resulted in availability of a wide range of devices for delivery of inhaled drugs. The four different delivery systems -- pressurized metered-dose inhalers, slow mist inhalers, dry powder inhalers, and nebulizers -- are unique in design and require distinct inhalational instructions for correct use. This book provides current information about inhalation devices, including their advantages and disadvantages, with guidance for optimal techniques of use. The book emphasizes appropriate selection of inhalation devices based on patient and health care professional factors as well as device attributes that allow selection of the right medication in the right inhalation device at the right time for the right patient. Key Features: • Addresses the objective of precision medicine – the right medication in the right inhaler device at the right time. • Inputs by international thought leaders who have published widely on inhaled medications and/or inhaled delivery systems for clinicians, trainees and respiratory therapists. • Discusses the development of audio-based systems and smart inhalers for patient monitoring.
Optimization Of Aerosol Drug Delivery
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Author : Leon Gradon
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-11-30
Optimization Of Aerosol Drug Delivery written by Leon Gradon and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-11-30 with Medical categories.
Aerosol therapy has significantly improved the treatment of a variety of respiratory diseases. Besides the treatment of respiratory diseases there is currently also a great interest to use the lungs as a portal to introduce drugs for systemic therapy. The success of therapy with the application of aerosolized medicaments depends on the possibility to deliver the proper amount of drug to the appropriate sites in the respiratory system, thus limiting the side effects to a minimum. Aerosolized delivery of drugs to the lung is optimized if, for a given chemical composition of a medicine, the target of deposition and the required mass of drug to be deposited are precisely defined. The next step is the specification of the number of respirable particles or droplets, to be generated by appropriate devices. Another very important factor for successful aerosol therapy is the condition of the patient coupled with his or her inhalation technique.