Inhalation Studies Foundations Techniques
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Inhalation Studies Foundations Techniques
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Author : R F. Phalen
language : en
Publisher:
Release Date : 1994
Inhalation Studies Foundations Techniques written by R F. Phalen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.
Inhalation Studies Foundations And Techniques
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Author : RF. PHALEN
language : en
Publisher:
Release Date : 1984
Inhalation Studies Foundations And Techniques written by RF. PHALEN and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.
Inhalation Studies
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Author : Robert F. Phalen
language : en
Publisher: CRC Press
Release Date : 2008-10-22
Inhalation Studies written by Robert F. Phalen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-22 with Medical categories.
This significantly updated and expanded new edition presents the scientific foundations of inhalation research essential to the design and conduct of toxicologic studies. It incorporates the major advances that have been made in the field, including recent advances in biology and the rapidly increasing global concerns and studies on particulate air pollution. The Second Edition was motivated by: new developments in the ultrafine particle health effects and concentrated aerosol research advances in understanding postnatal lung growth and the deposition and clearance of inhaled particles new techniques in toxicity testing the explosion of knowledge in the genetic and molecular realms the introduction of a large number of transgenic animal models updated ethical guidelines for animal testing the emergence of aerosol medicine the growing threat of aerosol-related terrorism increased appreciation of nonpulmonary effects of inhaled substances use of medical scanning techniques to study respiratory tract structure the introduction of new inhalation exposure systems the emergence of aerosol concentrators for use in air pollution studies
Methods In Inhalation Toxicology
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Author : Robert F. Phalen
language : en
Publisher: CRC Press
Release Date : 1996-11-06
Methods In Inhalation Toxicology written by Robert F. Phalen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-11-06 with Medical categories.
Conducting studies of natural and man-made air contaminants is a specialized research activity that draws upon skills from a variety of disciplines including toxicology, pharmacology, industrial hygiene, and environmental health. Methods in Inhalation Toxicology describes how knowledge from these disciplines is integrated into the design and conduct of inhalation studies. Each of the vital aspects of conducting these studies is discussed in detail, including the use of animal subjects and the related quality control and ethical considerations, air purification methodology, exposure atmosphere generation and characterization, inhalation exposure systems, and real-time and post-exposure biological assessments. These methods will enable you to conduct inhalation studies, easily adding any specific measures of particular interest to your research. The book covers techniques needed to: provide suitable clean air for experiments correctly generate the particles and gases being studied select the proper exposure system monitor the exposure prepare tissues for study ensure that animals do not have confounding lung disease The helpful descriptions and detailed lists of suppliers of preferred equipment and materials will help you to perform valid, reproducible inhalation toxicology studies. Methods in Inhalation Toxicology is a perfect textbook for students in toxicology programs, as well as for scientists who conduct inhalation studies in both academic and industrial environments.
Inhalation Studies
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Author : Robert F. Phalen
language : en
Publisher: CRC PressI Llc
Release Date : 1984
Inhalation Studies written by Robert F. Phalen and has been published by CRC PressI Llc this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Medical categories.
1. Aerosol and gases; 2. Basic morphology and physiology of the respiratory tract; 3. Establishing and controlling exposure environments; 4. Characterizing the exposure; 5. Methods for exposure animals.
Methods In Inhalation Toxicology
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Author : Robert F. Phalen
language : en
Publisher: CRC Press
Release Date : 2020-04-30
Methods In Inhalation Toxicology written by Robert F. Phalen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-30 with Medical categories.
This book focuses on an important aspect of the methods in laboratory animal inhalation toxicology. It is targeted to students in toxicology programs and scientists contemplating performing inhalation studies.
Concepts In Inhalation Toxicology
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Author : Roger O. McClellan
language : en
Publisher: CRC Press
Release Date : 1995-09-25
Concepts In Inhalation Toxicology written by Roger O. McClellan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-09-25 with Medical categories.
Recent developments have provided new data on the subject of inhalation toxicology, requiring an update of the previous edition of this popular text. Like the first, this second edition explains the basic concepts and quantitative approaches in inhalation toxicology, and it gives a comprehensive treatment of evaluations of respiratory responses to inhaled particles and gases. The author here explores new understanding of the role of cytokines in pulmonary inflammation and risk assessment. Immunologists, oncologists, respiratory specialists and students in those fields will find Concepts In Inhalation Toxicology to be essential to their practice.
The Particulate Air Pollution Controversy
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Author : Robert F. Phalen
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-08
The Particulate Air Pollution Controversy written by Robert F. Phalen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-08 with Science categories.
Small invisible particles in the urban air, especially those produced by human activities, have recently stimulated intense scrutiny, debate, regulation, and legal proceedings. The stakes are high, both with respect to health impacts and economic costs, and the methods used previously to resolve similar issues are no longer adequate. Everyone on earth inhales thousands to millions of particles in each breath, so if urban particulate air pollution—particulate matter (PM)—is significantly hazardous, the negative impact on health could be staggering. Yet the activities that generate PM, such as farming, manufacturing, mining, transportation, and generating electricity, are themselves essential to human health and welfare. Scientists, regulators, legislators, activists, judges, lawyers, journalists, and representatives of the business community are actively involved in addressing the question of what should be done. This complex issue presents opportunities for critically assessing the relevant knowledge and for adopting more rigorous approaches to this and similar problems. What is the PM controversy, and why is it a good case study for how science and public policy might better interface? The PM controversy is the sum of the frequently heated debates related to the potential health risks from urban PM.
Human And Ecological Risk Assessment
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Author : Dennis J. Paustenbach
language : en
Publisher: John Wiley & Sons
Release Date : 2024-04-15
Human And Ecological Risk Assessment written by Dennis J. Paustenbach and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-15 with Technology & Engineering categories.
Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.
Overcoming Challenges To Develop Countermeasures Against Aerosolized Bioterrorism Agents
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-09-07
Overcoming Challenges To Develop Countermeasures Against Aerosolized Bioterrorism Agents written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-07 with Political Science categories.
The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The book recommends that all unclassified data on bioterrorism agent studies-including unclassified, unpublished data from U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)-be published in the open literature. The book also calls on the U.S. Food and Drug Administration to improve the process by which bioterrorism countermeasures are approved based on the results of animal studies.