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Inhalation Toxicology Studies Of Aerosolized Products


Inhalation Toxicology Studies Of Aerosolized Products
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Inhalation Toxicology Studies Of Aerosolized Products Final Report


Inhalation Toxicology Studies Of Aerosolized Products Final Report
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Author : United States. Food and Drug Administration
language : en
Publisher:
Release Date : 1979

Inhalation Toxicology Studies Of Aerosolized Products Final Report written by United States. Food and Drug Administration and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Aerosols categories.




Inhalation Toxicology Studies Of Aerosolized Products


Inhalation Toxicology Studies Of Aerosolized Products
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Author :
language : en
Publisher:
Release Date : 1980

Inhalation Toxicology Studies Of Aerosolized Products written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with categories.




Inhalation Toxicology


Inhalation Toxicology
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Author : Ulrich Mohr
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07

Inhalation Toxicology written by Ulrich Mohr and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.


The International Life Sciences Institute (ILSI), a nonprofit, public foundation, was established in 1978 to advance the sciences of nutrition, toxicology, and food safety. ILSI promotes the resolution of health and safety issues in these areas by sponsoring research, conferences, publications, and educational programs. Through ILSI's programs, scientists from government, academia, and industry unite their efforts to resolve issues of critical importance to the public. As part of its commitment to understanding and resolving health and safety issues, ILSI is pleased to sponsor this series of monographs that consolidates new scientific knowledge, defines research needs, and provides a background for the effective application of scientific advances in toxicology and food safety. Alex Malaspina President International Life Sciences Institute Contents Series Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi Part I. Approaches to Assessing the Toxicity of Airborne Toxicants Chapter 1. Standard-Setting as an Integrative Exercise: Alchemy, Juggling, or Science? . . . . . . . . . . . . . . . . . . . . . . . 1 D. v. Bates Chapter 2. Species Differences in Inhalation Toxicology: Variations in Exposure-Dose Relationships and Macrophage Function. . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 J. D. Brain Chapter 3. Cell Populations of the Respiratory System: Interspecies Diversity in Composition, Distribution, and Morphology . . . . . . . . . . . . . . . . . . . . . . . . 25 e. G. Plopper, A. Mir, J. St. George, N. Tyler, A. Mariassy, D. Wilson, S. Nishio, D. Cranz, J. Heidsiek, and D. Hyde Chapter 4. Comparative Metabolic Basis for the Disposition and Toxic Effects of Inhaled Materials . . . . . . . . . . . . . . . . . 41 A. R. Dahl Part II. Methodological Issues in Designing and Conducting Studies with Laboratory Animals Chapter 5. Exposure Facilities and Aerosol Generation and Characterization for Inhalation Experiments. . . . . . . . . .



Inhalation Toxicology


Inhalation Toxicology
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Author : Harry Salem
language : en
Publisher: CRC Press
Release Date : 2005-12-22

Inhalation Toxicology written by Harry Salem and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-22 with Medical categories.


Written by internationally recognized scientists from academic, industrial, and governmental sectors, Inhalation Toxicology, Second Edition details the methods and materials used in the theoretical and applied aspects of inhalation toxicology. The editors emphasize the relationship between the respiratory system and toxicology of inhaled substances



Methods In Inhalation Toxicology


Methods In Inhalation Toxicology
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Author : Robert F. Phalen
language : en
Publisher: CRC Press
Release Date : 1996-11-06

Methods In Inhalation Toxicology written by Robert F. Phalen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-11-06 with Medical categories.


Conducting studies of natural and man-made air contaminants is a specialized research activity that draws upon skills from a variety of disciplines including toxicology, pharmacology, industrial hygiene, and environmental health. Methods in Inhalation Toxicology describes how knowledge from these disciplines is integrated into the design and conduct of inhalation studies. Each of the vital aspects of conducting these studies is discussed in detail, including the use of animal subjects and the related quality control and ethical considerations, air purification methodology, exposure atmosphere generation and characterization, inhalation exposure systems, and real-time and post-exposure biological assessments. These methods will enable you to conduct inhalation studies, easily adding any specific measures of particular interest to your research. The book covers techniques needed to: provide suitable clean air for experiments correctly generate the particles and gases being studied select the proper exposure system monitor the exposure prepare tissues for study ensure that animals do not have confounding lung disease The helpful descriptions and detailed lists of suppliers of preferred equipment and materials will help you to perform valid, reproducible inhalation toxicology studies. Methods in Inhalation Toxicology is a perfect textbook for students in toxicology programs, as well as for scientists who conduct inhalation studies in both academic and industrial environments.



Concepts In Inhalation Toxicology


Concepts In Inhalation Toxicology
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Author : Roger O. McClellan
language : en
Publisher: CRC Press
Release Date : 1995-09-25

Concepts In Inhalation Toxicology written by Roger O. McClellan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-09-25 with Medical categories.


Recent developments have provided new data on the subject of inhalation toxicology, requiring an update of the previous edition of this popular text. Like the first, this second edition explains the basic concepts and quantitative approaches in inhalation toxicology, and it gives a comprehensive treatment of evaluations of respiratory responses to inhaled particles and gases. The author here explores new understanding of the role of cytokines in pulmonary inflammation and risk assessment. Immunologists, oncologists, respiratory specialists and students in those fields will find Concepts In Inhalation Toxicology to be essential to their practice.



Inhalation Toxicology The Design And Interpretation Of Inhalation Studies And Their Use In Risk Assessment


Inhalation Toxicology The Design And Interpretation Of Inhalation Studies And Their Use In Risk Assessment
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Author : U MOHR (Ed)
language : en
Publisher:
Release Date : 1988

Inhalation Toxicology The Design And Interpretation Of Inhalation Studies And Their Use In Risk Assessment written by U MOHR (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with categories.


APPROACHES TO ASSESSING THE TOXICITY OF AIRBORNE TOXICANTS; STANDARD-SETTING AS AN INTEGRATIVE EXERCISE: ALCHEMY, JUGGLING, OR SCIENCE; SPECIES DIFFERENCES IN INHALATION TOXICOLOGY: VARIATIONS IN EXPOSURE-DOSE RELATIONSHIPS AND MACROPHAGE FUNCTION; CELL POPULATIONS OF THE RESPIRATORY SYSTEM: INTERSPECIES DIVERSITY IN COMPOSITION, DISTRIBUTION AND MORPHOLOGY; COMPARATIVE METABOLIC BASIS FOR THE DISPOSITION AND TOXIC EFFECTS OF INHALED MATERIALS; METHODOLOGICAL ISSUES IN DESIGNING AND CONDUCTING STUDIES WITH LABORATORY ANIMALS; EXPOSURE FACILITIES AND AEROSOL GENERATION AND CHARACTERIZATION FOR INHALATION EXPERIMENTS; DIFFERENT METHODS USED IN ACUTE AND SUBCHRONIC INHALATION STUDIES OF POTENTIAL LUNG IRRITANTS, WITH PARTICULAR ATTENTION TO LUNG FUNCTION; CHRONIC INHALATION TOXICITY STUDIES: PROTOCOLS AND PITFALLS; CARCINOGENICITY PROTOCOLS.



Inhalation Toxicology Third Edition


Inhalation Toxicology Third Edition
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Author : Harry Salem
language : en
Publisher: CRC Press
Release Date : 2014-08-19

Inhalation Toxicology Third Edition written by Harry Salem and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-19 with Medical categories.


The lungs provide a significant opportunity for the introduction of both therapeutic and toxic chemicals into the human body. In occupational and domestic environments, hazardous chemicals can enter the body through the lungs via gases, aerosols, and particulates from natural and anthropogenic sources. Fully updated with new research and discoveries since the last edition, Inhalation Toxicology, Third Edition presents contributions from internationally recognized scientists in the academic, commercial/industrial, and governmental sectors. A pragmatic resource for practicing professionals and students, the book comprehensively examines the relationship between the respiratory system and the toxicology of inhaled substances. Topics include: Regulatory aspects of exposure and testing Testing equipment and procedures Respiratory allergy and irritation of the respiratory tract Risk assessment Toxicology theory Toxicology modeling Toxic effects of some individual toxicants New topics in this third edition include collection and characterization of airborne particulate matter, the inhalation toxicology of asbestos fibers and nanoparticles, and the development of lung-on-a-chip technology for predicting in vivo responses. Each chapter concludes with thought-provoking questions and answers, enhancing the book’s educational utility.



Inhalation Studies


Inhalation Studies
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Author : Robert F. Phalen
language : en
Publisher: CRC Press
Release Date : 2008-10-22

Inhalation Studies written by Robert F. Phalen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-22 with Medical categories.


This significantly updated and expanded new edition presents the scientific foundations of inhalation research essential to the design and conduct of toxicologic studies. It incorporates the major advances that have been made in the field, including recent advances in biology and the rapidly increasing global concerns and studies on particulate air pollution. The Second Edition was motivated by: new developments in the ultrafine particle health effects and concentrated aerosol research advances in understanding postnatal lung growth and the deposition and clearance of inhaled particles new techniques in toxicity testing the explosion of knowledge in the genetic and molecular realms the introduction of a large number of transgenic animal models updated ethical guidelines for animal testing the emergence of aerosol medicine the growing threat of aerosol-related terrorism increased appreciation of nonpulmonary effects of inhaled substances use of medical scanning techniques to study respiratory tract structure the introduction of new inhalation exposure systems the emergence of aerosol concentrators for use in air pollution studies



Pharmaceutical Inhalation Aerosol Technology


Pharmaceutical Inhalation Aerosol Technology
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Author : Anthony J. Hickey
language : en
Publisher: CRC Press
Release Date : 1992

Pharmaceutical Inhalation Aerosol Technology written by Anthony J. Hickey and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.


This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.