Innovations In Modeling And Simulation To Advance Translational Science


Innovations In Modeling And Simulation To Advance Translational Science
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Innovations In Modeling And Simulation To Advance Translational Science


Innovations In Modeling And Simulation To Advance Translational Science
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Author : Melissa Knothe Tate
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-15

Innovations In Modeling And Simulation To Advance Translational Science written by Melissa Knothe Tate and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-15 with Science categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Innovations In Biomolecular Modeling And Simulations


Innovations In Biomolecular Modeling And Simulations
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Author : Tamar Schlick
language : en
Publisher: Royal Society of Chemistry
Release Date : 2012-05-24

Innovations In Biomolecular Modeling And Simulations written by Tamar Schlick and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-24 with Science categories.


The chemical and biological sciences face unprecedented opportunities in the 21st century. A confluence of factors from parallel universes - advances in experimental techniques in biomolecular structure determination, progress in theoretical modeling and simulation for large biological systems, and breakthroughs in computer technology - has opened new avenues of opportunity as never before. Now, experimental data can be interpreted and further analysed by modeling, and predictions from any approach can be tested and advanced through companion methodologies and technologies. This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts. With contributions from experts in the field, the books describe progress and innovation in areas including: simulation algorithms for dynamics and enhanced configurational sampling, force field development, implicit solvation models, coarse-grained models, quantum-mechanical simulations, protein folding, DNA polymerase mechanisms, nucleic acid complexes and simulations, RNA structure analysis and design and other important topics in structural biology modeling. The books are aimed at graduate students and experts in structural biology and chemistry and the emphasis is on reporting innovative new approaches rather than providing comprehensive reviews on each subject.



Innovations In Biomolecular Modeling And Simulations


Innovations In Biomolecular Modeling And Simulations
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Author : Tamar Schlick
language : en
Publisher:
Release Date : 2012

Innovations In Biomolecular Modeling And Simulations written by Tamar Schlick and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Science categories.


This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts.



Advances In Modeling And Simulation


Advances In Modeling And Simulation
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Author : Andreas Tolk
language : en
Publisher: Springer
Release Date : 2017-08-27

Advances In Modeling And Simulation written by Andreas Tolk and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-27 with Computers categories.


​This broad-ranging text/reference presents a fascinating review of the state of the art of modeling and simulation, highlighting both the seminal work of preeminent authorities and exciting developments from promising young researchers in the field. Celebrating the 50th anniversary of the Winter Simulation Conference (WSC), the premier international forum for disseminating recent advances in the field of system simulation, the book showcases the historical importance of this influential conference while also looking forward to a bright future for the simulation community. Topics and features: examines the challenge of constructing valid and efficient models, emphasizing the benefits of the process of simulation modeling; discusses model calibration, input model risk, and approaches to validating emergent behaviors in large-scale complex systems with non-linear interactions; reviews the evolution of simulation languages, and the history of the Time Warp algorithm; offers a focus on the design and analysis of simulation experiments under various goals, and describes how data can be “farmed” to support decision making; provides a comprehensive overview of Bayesian belief models for simulation-based decision making, and introduces a model for ranking and selection in cloud computing; highlights how input model uncertainty impacts simulation optimization, and proposes an approach to quantify and control the impact of input model risk; surveys the applications of simulation in semiconductor manufacturing, in social and behavioral modeling, and in military planning and training; presents data analysis on the publications from the Winter Simulation Conference, offering a big-data perspective on the significant impact of the conference. This informative and inspiring volume will appeal to all academics and professionals interested in computational and mathematical modeling and simulation, as well as to graduate students on the path to form the next generation of WSC pioneers.



Comprehensive Healthcare Simulation Anesthesiology


Comprehensive Healthcare Simulation Anesthesiology
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Author : Bryan Mahoney
language : en
Publisher: Springer Nature
Release Date : 2019-12-17

Comprehensive Healthcare Simulation Anesthesiology written by Bryan Mahoney and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-17 with Medical categories.


This book functions as a practical guide for the use of simulation in anesthesiology. Divided into five parts, it begins with the history of simulation in anesthesiology, its relevant pedagogical principles, and the modes of its employment. Readers are then provided with a comprehensive review of simulation technologies as employed in anesthesiology and are guided on the use of simulation for a variety of learners: undergraduate and graduate medical trainees, practicing anesthesiologists, and allied health providers. Subsequent chapters provide a ‘how-to” guide for the employment of simulation across wide range of anesthesiology subspecialties before concluding with a proposed roadmap for the future of translational simulation in healthcare. The Comprehensive Textbook of Healthcare Simulation: Anesthesiology is written and edited by leaders in the field and includes hundreds of high-quality color surgical illustrations and photographs.



Energetic Materials


Energetic Materials
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Author : Mark J. Mezger
language : en
Publisher: CRC Press
Release Date : 2017-07-06

Energetic Materials written by Mark J. Mezger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with Technology & Engineering categories.


This book will take an in-depth look at the technologies, processes, and capabilities to develop and produce "next generation" energetic materials for both commercial and defense applications, including military, mining operations, oil production and well perforation, and construction demolition. It will serve to highlight the critical technologies, latest developments, and the current capability gaps that serve as barriers to military fielding or transition to the commercial marketplace. It will also explain how the processing technologies can be spun out for use in other non-energetics related industries.



Systems Pharmacology And Pharmacodynamics


Systems Pharmacology And Pharmacodynamics
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Author : Donald E. Mager
language : en
Publisher: Springer
Release Date : 2016-11-29

Systems Pharmacology And Pharmacodynamics written by Donald E. Mager and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-29 with Medical categories.


While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found in proof-of-concept and/or Phase II studies. Systems Pharmacology and Pharmacodynamics discusses the framework for integrating information obtained from understanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targets in order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation.



Computational Methods And Models For Transport


Computational Methods And Models For Transport
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Author : Pedro Diez
language : en
Publisher: Springer
Release Date : 2017-06-28

Computational Methods And Models For Transport written by Pedro Diez and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-28 with Technology & Engineering categories.


This volume addresses challenges and solutions in transport and mobility of people and goods with respect to environment, safety, security and socio–economics issues, exploring advanced computational research work and the latest innovations in transport. This book brings together lectures presented at the ECCOMAS Thematic CM3 Conference on Transport held in Jyväskylä, Finland, 25-27 May 2015. It is divided into three parts, I: Reviews and Perspective, II: Computational Methods and Models and III: Translational Research. Each of these parts consists of contributions that present solutions to many transport challenges in this complex, rapidly changing subject. The work contains the latest achievements of European research and technological developments needed for the next decade through computational results of scientific and technical experts who have made essential contributions in transport efficiency in Europe. The material presented here is the state of the art in Transport Modeling, Simulation and Optimization in the fields of Aeronautics, Automotive, Logistics, Maritime and Rails. Furthermore, this volume also answers the question how to apply Computational Research in Transport in order to provide innovative solutions to Green Transportation challenges of identified in the ambitious Horizon 2020 program. This book is intended for students, researchers, engineers and practitioners that are computationally involved in the deployment of Intelligent Transport Systems (ITS) in the areas of optimal use of road, traffic and travel data, traffic and freight management ITS services, road safety and security, sea traffic management, etc.



An Investigation Report On Large Public Hospital Reforms In China


An Investigation Report On Large Public Hospital Reforms In China
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Author : Lulu Zhang
language : en
Publisher: Springer
Release Date : 2015-12-08

An Investigation Report On Large Public Hospital Reforms In China written by Lulu Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-08 with Medical categories.


This book provides a comprehensive understanding of public hospital reform in China, which is a hot topic for China’s new round of health sector reform. The authors use rich data from both health provider side and service user side and conduct a cross-sectional study in China with some comparative analysis between different locations. It provides the audience with a big picture of China’s public hospital and other components of health system as well. The book reviews the main policy measurements in the public hospital reforms and evaluates how these policies influence public hospitals' practices, especially on hospital governance and internal management.



Journal Of The House Of Representatives Of The United States


Journal Of The House Of Representatives Of The United States
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Author : United States. Congress. House
language : en
Publisher:
Release Date : 1973

Journal Of The House Of Representatives Of The United States written by United States. Congress. House and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with Legislation categories.


Some vols. include supplemental journals of "such proceedings of the sessions, as, during the time they were depending, were ordered to be kept secret, and respecting which the injunction of secrecy was afterwards taken off by the order of the House".