Innovative Dosage Forms
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Innovative Dosage Forms
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Author : Yogeshwar Bachhav
language : en
Publisher: John Wiley & Sons
Release Date : 2019-12-04
Innovative Dosage Forms written by Yogeshwar Bachhav and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-04 with Science categories.
Teaches future and current drug developers the latest innovations in drug formulation design and optimization This highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral administration routes. The book also discusses safety aspects of drugs and excipients, as well as regulatory issues relevant to formulation. Innovative Dosage Forms: Design and Development at Early Stage starts with a look at the impact of the polymorphic form of drugs on the preformulation and formulation development. It then offers readers reliable strategies for the formulation development of poorly soluble drugs. The book also studies the role of reactive impurities from the excipients on the formulation shelf life; preclinical formulation assessment of new chemical entities; and regulatory aspects for formulation design. Other chapters cover innovative formulations for special indications, including oncology injectables, delayed release and depot formulations; accessing pharmacokinetics of various dosage forms; physical characterization techniques to assess amorphous nature; novel formulations for protein oral dosage; and more. -Provides information that is essential for the drug development effort -Presents the latest advances in the field and describes in detail innovative formulations, such as nanosuspensions, micelles, and cocrystals -Describes current approaches in early pre-formulation to achieve the best in vivo results -Addresses regulatory and safety aspects, which are key considerations for pharmaceutical companies -Includes case studies from recent drug development programs to illustrate the practical challenges of preformulation design Innovative Dosage Forms: Design and Development at Early Stage provides valuable benefits to interdisciplinary drug discovery teams working in industry and academia and will appeal to medicinal chemists, pharmaceutical chemists, and pharmacologists.
How To Develop Robust Solid Oral Dosage Forms
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Author : Bhavishya Mittal
language : en
Publisher: Academic Press
Release Date : 2016-10-05
How To Develop Robust Solid Oral Dosage Forms written by Bhavishya Mittal and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-05 with Medical categories.
How to Develop Robust Solid Oral Dosage Forms from Conception to Post-Approval uses a practical and hands-on approach to cover the development process of solid oral dosage forms in one single source. The book details all of the necessary steps from formulation through the post-approval phase and contains industry case studies, real world advice, and troubleshooting tips. By merging the latest scientific information with practical instructions, this book provides pharmaceutical scientists in formulation research and development with a concrete look at the key aspects in the development of solid oral dosage forms. - Focuses on important topics, such as robustness, bioavailability, formulation design, continuous processing, stability tests, modified release dosage forms, international guidelines, process scale-up, and much more - Part of the Expertise in Pharmaceutical Process Technology series edited by Michael Levin - Discusses common, real-world problems and offers both theoretical and practical solutions to these everyday issues
Drug Delivery Systems Principles Innovations In Pharmaceutical Formulations
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Author : Mr. Darshan Lalwani
language : en
Publisher: RK Publication
Release Date : 2024-10-09
Drug Delivery Systems Principles Innovations In Pharmaceutical Formulations written by Mr. Darshan Lalwani and has been published by RK Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-09 with Business & Economics categories.
The book, explores the evolution, types, and current trends in drug delivery. It covers foundational concepts of drug delivery systems (DDS), focusing on techniques designed to maximize therapeutic efficacy and patient compliance. Through in-depth discussions on diverse delivery methods such as oral, transdermal, and nanotechnology-based systems, the book examines the challenges and innovations in targeting specific cells and sustaining drug release. With special emphasis on case studies, personalized medicine, and ethical considerations, it also highlights regulatory guidelines and future directions for drug delivery in modern healthcare. This comprehensive guide serves as a crucial resource for professionals in pharmaceutical science, providing insights into the advancements and complexities of DDS technology in optimizing patient outcomes.
Innovative Delivery Systems For Paediatric Medicines
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Author : Jenny Walsh (Pharmacist)
language : en
Publisher: World Health Organization
Release Date : 2021-11-10
Innovative Delivery Systems For Paediatric Medicines written by Jenny Walsh (Pharmacist) and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-10 with Medical categories.
Provided in this landscape analysis is an overview of new and emerging dosage forms and formulation technologies that may be beneficial if applied for use in paediatric patients. It covers various routes of administration including oral, rectal, parenteral, transdermal and others. There is also attention given to long-acting formulations that hold clear promise for use in children. Emphasis is placed upon those dosage forms and technologies which could be suitable for use for children in LMICs. There are key considerations when analysing potential application of these technologies to existing and emerging therapeutic needs for children. Some technologies are ready and available to use in an intervention today, while others will require further investigations. As a result, strategic interventions and investments in this area can be classified by opportunities in the short-term and in the long-term. There are near-term opportunities for the development of age-appropriate solid oral dosage forms including dispersible tablet formulations and oro-dispersible tablets. Also, suppositories and long-acting depot injectables offer potential alternatives and are gaining interest. Well established technologies for controlling and delaying release and for enhancing the bioavailability of poorly soluble drugs are all considered to provide near term opportunities. On the longer term, further evaluation of the safety and acceptability of some of the dosage forms and technologies in paediatric patients are required, as well as, the feasibility for cost-effective commercialisation. (i.e., oro-dispersible and buccal films, long acting implants, and needle-free injections).
Innovative Dosage Forms
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Author : Yogeshwar Bachhav
language : en
Publisher: John Wiley & Sons
Release Date : 2019-08-20
Innovative Dosage Forms written by Yogeshwar Bachhav and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-20 with Science categories.
Teaches future and current drug developers the latest innovations in drug formulation design and optimization This highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral administration routes. The book also discusses safety aspects of drugs and excipients, as well as regulatory issues relevant to formulation. Innovative Dosage Forms: Design and Development at Early Stage starts with a look at the impact of the polymorphic form of drugs on the preformulation and formulation development. It then offers readers reliable strategies for the formulation development of poorly soluble drugs. The book also studies the role of reactive impurities from the excipients on the formulation shelf life; preclinical formulation assessment of new chemical entities; and regulatory aspects for formulation design. Other chapters cover innovative formulations for special indications, including oncology injectables, delayed release and depot formulations; accessing pharmacokinetics of various dosage forms; physical characterization techniques to assess amorphous nature; novel formulations for protein oral dosage; and more. -Provides information that is essential for the drug development effort -Presents the latest advances in the field and describes in detail innovative formulations, such as nanosuspensions, micelles, and cocrystals -Describes current approaches in early pre-formulation to achieve the best in vivo results -Addresses regulatory and safety aspects, which are key considerations for pharmaceutical companies -Includes case studies from recent drug development programs to illustrate the practical challenges of preformulation design Innovative Dosage Forms: Design and Development at Early Stage provides valuable benefits to interdisciplinary drug discovery teams working in industry and academia and will appeal to medicinal chemists, pharmaceutical chemists, and pharmacologists.
Pharmaceutical Formulation
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Author : Geoffrey D Tovey
language : en
Publisher: Royal Society of Chemistry
Release Date : 2018-06-25
Pharmaceutical Formulation written by Geoffrey D Tovey and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-25 with Science categories.
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
Dosage Form Design Parameters
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Author :
language : en
Publisher: Academic Press
Release Date : 2018-07-27
Dosage Form Design Parameters written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-27 with Medical categories.
Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.
Pharmaceutical Dosage Forms
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Author : Sandeep Nema
language : en
Publisher: CRC Press
Release Date : 2010-08-26
Pharmaceutical Dosage Forms written by Sandeep Nema and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-26 with Medical categories.
Pharmaceutical Dosage Forms: Parenteral Medications explores the administration of medications through other than the enteral route. First published in 1984 (as two volumes) and then last revised in 1993, this three-volume set presents the plethora of changes in the science and considerable advances in the technology associated with these products
Pharmaceutical Dosage Forms Parenteral Medications
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Author : Sandeep Nema
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Pharmaceutical Dosage Forms Parenteral Medications written by Sandeep Nema and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
This three-volume set of Pharmaceutical Dosage Forms: Parenteral Medications is an authoritative, comprehensive reference work on the formulation and manufacture of parenteral dosage forms, effectively balancing theoretical considerations with the practical aspects of their development. As such, it is recommended for scientists and engineers in the
Computational Drug Delivery
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Author : Pooja A. Chawla
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2024-10-07
Computational Drug Delivery written by Pooja A. Chawla and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-07 with Science categories.
The book bridges the gap between pharmaceutics and molecular modelling at the micro, meso and macro scale. It covers Lipinski's rule of five, nanoparticulate drug delivery, computational prediction of drug solubility and ability to cross blood brain barrier, computer-based simulation of pharmacokinetic parameters, virtual screening of mucoadhesive polymers, QSPR modelling, designing of 2D nanomaterials and role of principal component analysis.