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Integrative Bioinformatics


Integrative Bioinformatics
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Integrative Bioinformatics


Integrative Bioinformatics
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Author : Ming Chen
language : en
Publisher: Springer Nature
Release Date : 2022-04-15

Integrative Bioinformatics written by Ming Chen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-15 with Medical categories.


This book provides an overview of the history of integrative bioinformatics and the actual situation and the relevant tools. Subjects cover the essential topics, basic introductions, and latest developments; biological data integration and manipulation; modeling and simulation of networks; as well as a number of applications of integrative bioinformatics. It aims to provide basic introduction of biological information systems and guidance for the computational analysis of systems biology. This book covers a range of issues and methods that unveil a multitude of omics data integration and relevance that integrative bioinformatics has today. It contains a unique compilation of invited and selected articles from the Journal of Integrative Bioinformatics (JIB) and annual meetings of the International Symposium on Integrative Bioinformatics.



Approaches In Integrative Bioinformatics


Approaches In Integrative Bioinformatics
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Author : Ming Chen
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-18

Approaches In Integrative Bioinformatics written by Ming Chen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-18 with Computers categories.


Approaches in Integrative Bioinformatics provides a basic introduction to biological information systems, as well as guidance for the computational analysis of systems biology. This book also covers a range of issues and methods that reveal the multitude of omics data integration types and the relevance that integrative bioinformatics has today. Topics include biological data integration and manipulation, modeling and simulation of metabolic networks, transcriptomics and phenomics, and virtual cell approaches, as well as a number of applications of network biology. It helps to illustrate the value of integrative bioinformatics approaches to the life sciences. This book is intended for researchers and graduate students in the field of Bioinformatics. Professor Ming Chen is the Director of the Bioinformatics Laboratory at the College of Life Sciences, Zhejiang University, Hangzhou, China. Professor Ralf Hofestädt is the Chair of the Department of Bioinformatics and Medical Informatics, Bielefeld University, Germany.



Integrative Bioinformatics For Biomedical Big Data


Integrative Bioinformatics For Biomedical Big Data
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Author : Xiuzhen Huang
language : en
Publisher: Cambridge University Press
Release Date : 2023-10-31

Integrative Bioinformatics For Biomedical Big Data written by Xiuzhen Huang and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-31 with Science categories.


The volume and complexity of biological and biomedical research continues to grow exponentially with cutting-edge technologies such as high-throughput DNA sequencing. Unfortunately, bioinformatics analysis is often considered only after data has been generated, which significantly limits the ability to make sense of complex Big Data. This unique book introduces the idea of no-boundary thinking (NBT) in biological and biomedical research, which aims to access, integrate, and synthesize data, information, and knowledge from bioinformatics to define important problems and articulate impactful research questions. NBT encourages interdisciplinary thinking from the outset so that research is hypothesis-driven rather than data-driven. This interdisciplinary volume brings together a team of bioinformatics specialists who draw on their own experiences with NBT to illustrate the importance of collaborative science. It will help stimulate discussion and application of NBT, and will appeal to all biomedical researchers looking to maximize their use of bioinformatics for making scientific discoveries.



Integrative Cluster Analysis In Bioinformatics


Integrative Cluster Analysis In Bioinformatics
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Author : Basel Abu-Jamous
language : en
Publisher: John Wiley & Sons
Release Date : 2015-06-15

Integrative Cluster Analysis In Bioinformatics written by Basel Abu-Jamous and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-15 with Technology & Engineering categories.


Clustering techniques are increasingly being put to use in the analysis of high-throughput biological datasets. Novel computational techniques to analyse high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. This book details the complete pathway of cluster analysis, from the basics of molecular biology to the generation of biological knowledge. The book also presents the latest clustering methods and clustering validation, thereby offering the reader a comprehensive review of clustering analysis in bioinformatics from the fundamentals through to state-of-the-art techniques and applications. Key Features: Offers a contemporary review of clustering methods and applications in the field of bioinformatics, with particular emphasis on gene expression analysis Provides an excellent introduction to molecular biology with computer scientists and information engineering researchers in mind, laying out the basic biological knowledge behind the application of clustering analysis techniques in bioinformatics Explains the structure and properties of many types of high-throughput datasets commonly found in biological studies Discusses how clustering methods and their possible successors would be used to enhance the pace of biological discoveries in the future Includes a companion website hosting a selected collection of codes and links to publicly available datasets



Integrative Bioinformatics


Integrative Bioinformatics
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Author :
language : en
Publisher:
Release Date : 1998

Integrative Bioinformatics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.




Integrative Omics


Integrative Omics
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Author : Manish Kumar Gupta
language : en
Publisher: Elsevier
Release Date : 2024-05-10

Integrative Omics written by Manish Kumar Gupta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-10 with Science categories.


Integrative Omics: Concepts, Methodology and Applications provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference includes a range of chapters in a systemic ‘step by step’ manner, which begins with the basic concepts from Omic to Multi Integrative Omics approaches, followed by their full range of approaches, applications, emerging trends, and future trends. All key areas of Omics are covered including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics as well as omics technology policy and society research. Integrative Omics: Concepts, Methodology and Applications highlights the recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science. The book bridges the gap between biological sciences, physical sciences, computer science, statistics, data science, information technology and mathematics by presenting content specifically dedicated to mathematical models of biological systems. Provides a holistic, integrated view of a defining and applying network approach, integrative tools, and methods to solve problems for rationalization of genotype to phenotype relationships Offers an interdisciplinary approach to Databases, data analytics techniques, biological tools, network construction, analysis, modeling, prediction and simulation of biological systems leading to ‘translational research’, i.e., drug discovery, drug target prediction, and precision medicine Covers worldwide methods, concepts, databases, and tools used in the construction of integrated pathways



Integrative Bioinformatics Approaches For Dynamic Time Series And Steady State Transcriptome Microarray Data


Integrative Bioinformatics Approaches For Dynamic Time Series And Steady State Transcriptome Microarray Data
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Author : 盧子彬
language : en
Publisher:
Release Date : 2011

Integrative Bioinformatics Approaches For Dynamic Time Series And Steady State Transcriptome Microarray Data written by 盧子彬 and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.




Systems Biology


Systems Biology
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Author : Aleš Prokop
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-08-28

Systems Biology written by Aleš Prokop and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-28 with Medical categories.


Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing patent protection or being withdrawn from the market are simply not being replaced by new therapies – the pharmaceutical market model is no longer functioning effectively and most pharmaceutical companies are failing to produce the innovation needed for success. This multi-authored new book looks at a vital strategy which can bring innovation to a market in need of new ideas and new products: Systems Biology (SB). Modeling is a significant task of systems biology. SB aims to develop and use efficient algorithms, data structures, visualization and communication tools to orchestrate the integration of large quantities of biological data with the goal of computer modeling. It involves the use of computer simulations of biological systems, such as the networks of metabolites comprise signal transduction pathways and gene regulatory networks to both analyze and visualize the complex connections of these cellular processes. SB involves a series of operational protocols used for performing research, namely a cycle composed of theoretical, analytic or computational modeling to propose specific testable hypotheses about a biological system, experimental validation, and then using the newly acquired quantitative description of cells or cell processes to refine the computational model or theory.



Exploring Microrna Biology Using Integrative Bioinformatics


Exploring Microrna Biology Using Integrative Bioinformatics
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Author : Yotsawat Pomyen
language : en
Publisher:
Release Date : 2014

Exploring Microrna Biology Using Integrative Bioinformatics written by Yotsawat Pomyen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.




Advances In Statistical Bioinformatics


Advances In Statistical Bioinformatics
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Author : Kim-Anh Do
language : en
Publisher: Cambridge University Press
Release Date : 2013-06-10

Advances In Statistical Bioinformatics written by Kim-Anh Do and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-10 with Mathematics categories.


This book describes the integration of high-throughput bioinformatics data from multiple platforms to inform our understanding of the functional consequences of genomic alterations.