Interaction Between The Gut Flora And Immunity In Intestinal Diseases
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Interaction Between The Gut Flora And Immunity In Intestinal Diseases
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Author : Yating Li
language : en
Publisher: Frontiers Media SA
Release Date : 2024-08-20
Interaction Between The Gut Flora And Immunity In Intestinal Diseases written by Yating Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-20 with Medical categories.
The composition of gut microbiota plays a critical role in maintaining the host's health, particularly in regulating immune homeostasis and the intestinal immune response. A massive effort has pointed to the importance of these interactions in various intestinal diseases like colorectal cancer (CRC), irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). Microbiome influences the formation of key components of both the innate and adaptive immune systems, while the immune system is responsible for regulating and maintaining the symbiotic relationship between the host and microbes. Currently, the crosstalk between gut flora and host immunity is not fully revealed in both homeostasis maintenance and disease development. Hence detailed mechanistic studies are needed to further explore the microbial manipulation on host immunity as well as the immune response to microbiome dysbiosis in intestinal diseases. Current evidence indicates a strong bidirectional interaction between microbiome perturbation and immune dysregulation. The aim of this Research Topic is to create a platform for the advancement of research on the causal relationship between the microbiome and immunity. Besides, we would like to define the core microbiota responsible for the initiation and progression of intestinal diseases, the molecular mechanisms of host immune-microbiome interactions, and novel gut-targeted pharmacological interventions to achieve a positive impact on intestinal disease.
Microbiome Host Interactions
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Author : D. Dhanasekaran
language : en
Publisher: CRC Press
Release Date : 2021-04-01
Microbiome Host Interactions written by D. Dhanasekaran and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-01 with Medical categories.
Microbiota are a promising and fascinating subject in biology because they integrate the microbial communities in humans, animals, plants, and the environment. In humans, microbiota are associated with the gut, skin, and genital, oral, and respiratory organs. The plant microbial community is referred to as "holobiont," and it is influential in the maintenance and health of plants, which themselves play a role in animal health and the environment. The contents of Microbiome-Host Interactions cover all areas as well as new research trends in the fields of plant, animal, human, and environmental microbiome interactions. The book covers microbiota in polar soil environments, in health and disease, in Caenorhabditis elegans, and in agroecosystems, as well as in rice root and actinorhizal root nodules, speleothems, and marine shallow-water hydrothermal vents. Moreover, this book provides comprehensive accounts of advanced next-generation DNA sequencing, metagenomic techniques, high-throughput 16S rRNA sequencing, and understanding nucleic acid sequence data from fungal, algal, viral, bacterial, cyanobacterial, actinobacterial, and archaeal communities using QIIME software (Quantitative Insights into Microbial Ecology). FEATURES Summarizes recent insight in microbiota and host interactions in distinct habitats, including Antarctic, hydrothermal vents, speleothems, oral, skin, gut, feces, reproductive tract, soil, root, root nodules, forests, and mangroves Illustrates the high-throughput amplicon sequencing, computational techniques involved in the microbiota analysis, downstream analysis and visualization, and multivariate analysis commonly used for microbiome analysis Describes probiotics and prebiotics in the composition of the gut microbiota, skin microbiome impact in dermatologic disease prevention, and microbial communities in the reproductive tract of humans and animals Presents information in a reachable way for students, teachers, researchers, microbiologists, computational biologists, and other professionals who are interested in strengthening or enlarging their knowledge about microbiome analysis with next-generation DNA sequencing in the different branches of the sciences
Probiotics And Prebiotics
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Author : Koen Venema
language : en
Publisher: Caister Academic Press Limited
Release Date : 2015
Probiotics And Prebiotics written by Koen Venema and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.
Composed of nearly a thousand different types of microorganisms - some beneficial, others not - the human gut microbiota plays an important role in health and disease. This is due to the presence of probiotic or beneficial microbes, or due to the feeding of prebiotics that stimulate the endogenous beneficial microbes (these promote health by stimulating the immune system, improving the digestion and absorption of nutrients, and inhibiting the growth of pathogens). The notable health benefits of probiotic organisms have prompted much commercial interest, which in turn has led to a plethora of research initiatives in this area. These range from studies to elucidate the efficacy of the various health benefits to analyses of the diet-microbe interaction as a means of modulating the gut microbiota composition. Research in this area is at a very exciting stage. With state-of-the-art commentaries on all aspects of probiotics and prebiotics research, this book provides an authoritative and timely overview of the field. Written by leading international researchers, each chapter affords critical insight to a particular topic, reviews current research, discusses future direction, and stimulates discussion. Topics range from the different microorganisms used as probiotics (lactobacilli, bifidobacteria, yeast, etc.), and the techniques and approaches used (metagenomics, etc.), to the reviews of the clinical and medical aspects. The provision of extensive reference sections positively encourages readers to pursue each subject in greater detail. *** Librarians: ebook available on ProQuest and EBSCO [Subject: Microbiology, Life Science]
One Health Meets Microbiota Interactions Between Digestive Tract Microbiota Host And Environment
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Author : Xiaodan Huang
language : en
Publisher: Frontiers Media SA
Release Date : 2024-05-06
One Health Meets Microbiota Interactions Between Digestive Tract Microbiota Host And Environment written by Xiaodan Huang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-06 with Science categories.
The Role Of Immune Checkpoints In Gastrointestinal Diseases
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Author : Qi Yang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-24
The Role Of Immune Checkpoints In Gastrointestinal Diseases written by Qi Yang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-24 with Medical categories.
Immunotherapy based on immune checkpoint molecules is gradually becoming an important treatment strategy for gastrointestinal tumours and inflammation. This Research Topic will focus on the role of immune checkpoint molecules in gastrointestinal inflammation and tumours, the latest progress in the corresponding regulatory mechanisms. Meanwhile, this topic explores the similarities and differences of different immune checkpoint molecules in tumours such as gastric cancer and colorectal cancer and inflammatory diseases such as inflammatory bowel diseases, intestinal-related sepsis, and peritoneal infection. Furthermore, not only limited to oncology treatment, the application of immune checkpoint inhibitors extends to inflammatory diseases of the gastrointestinal tract. Thus, immunotherapy targeting immune checkpoint molecules offers great promise for the treatment of gastrointestinal disorders. Immunotherapy is one of the most cutting-edge fields in the current treatment of gastrointestinal diseases. Immune checkpoint inhibitors have been gradually applied in the clinical treatment of gastrointestinal tumours and have been gradually explored in gastrointestinal inflammatory diseases. However, whether the expression of different immune checkpoint molecules affects the selection of immune checkpoint molecular inhibitors, how to combine different immune checkpoint molecular inhibitors, and how to screen outpatients responsive to immune checkpoint molecular inhibitors in urgent scientific questions to be addressed.
Spatially Variable Genes In Cancer Development Progression And Treatment Response
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Author : Raghavan, Ramya
language : en
Publisher: IGI Global
Release Date : 2024-12-17
Spatially Variable Genes In Cancer Development Progression And Treatment Response written by Raghavan, Ramya and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-17 with Medical categories.
Spatial variable genes (SVGs) in cancer refer to genes that exhibit different expression levels or patterns across different regions or cells within a tumor. Cancer-associated fibroblasts (CAFs) are a crucial component of the tumor microenvironment (TME), playing a fundamental role in tumor progression, metastasis, and therapy response. Identifying and characterizing SVGs can reveal novel targets for cancer treatment. Combining spatial transcriptomics with other omics data can provide a more comprehensive picture of tumor biology. Spatially Variable Genes in Cancer: Development, Progression, and Treatment Response illuminates the heterogeneity within tumors, challenging the traditional one-size-fits-all approach. The chapters examine how SVGs influence tumor biology and pave the way for novel diagnostic and therapeutic approaches. Covering topics such as bioengineering, gene expression, and tumor initiation, this book is an excellent resource for academicians, researchers, students, oncologists, medical professionals, medical administrators, scientists, and more.
The Role Of Gut Microbes And Their Metabolites In Immune Related Diseases
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Author :
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-06
The Role Of Gut Microbes And Their Metabolites In Immune Related Diseases written by and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-06 with Science categories.
Immune Responses And Therapeutics Of Inflammatory Bowel Disease
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Author : Salman Assad
language : en
Publisher: Lulu.com
Release Date : 2018-02-09
Immune Responses And Therapeutics Of Inflammatory Bowel Disease written by Salman Assad and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-09 with Science categories.
Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal tract associated with an imbalance of the intestinal microbiota. Crohn's disease (CD) and ulcerative colitis (UC) are the most widely known types of IBD and have been the focus of attention due to their increasing incidence. Recent studies have pointed out genes associated with IBD susceptibility that, together with environmental factors, may contribute to the outcome of the disease. In ulcerative colitis, there are several therapies available, depending on the stage of the disease. Aminosalicylates, corticosteroids, and cyclosporine are used to treat mild, moderate, and severe disease, respectively. Nowadays, advances in treatments for IBD have included biological therapies, based mainly on monoclonal antibodies or fusion proteins, such as anti-TNF drugs.
Applications Of Herbal Medicine To Control Chronic Kidney Disease
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Author : Jianping Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-21
Applications Of Herbal Medicine To Control Chronic Kidney Disease written by Jianping Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-21 with Science categories.
Interaction Between Traditional Chinese Medicine And Gut Microbiota
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Author : Xiaolin Tong
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-03
Interaction Between Traditional Chinese Medicine And Gut Microbiota written by Xiaolin Tong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-03 with Science categories.