Intercellular Communication In Cancer
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Intercellular Communication In Cancer
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Author : Mustapha Kandouz
language : en
Publisher: Springer
Release Date : 2015-11-20
Intercellular Communication In Cancer written by Mustapha Kandouz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-20 with Medical categories.
Cells are by nature compelled to live in groups. They develop dependence over signaling cues received from their microenvironment, in particular from other cells, whether of their own “kind” or of a different type. Therefore, communicating with these cells is a critical aspect of their behavior and fate, as they live and die normally or as they undergo disease-related pathological changes, with dramatic repercussions. In this book, we have asked expert researchers in the field of Intercellular Communication in Cancer to provide chapters on different aspects of interaction between neighboring cells, in the context of cancer diseases. We have specifically focused our efforts on membrane-to-membrane contact-based rather than growth factors-mediated modes of intercellular communications. The contributing authors provide an extensive overview of their respective area of specialization, with an in-depth discussion of the molecular mechanisms of cell-cell interactions, the impact on tumor progression and response to therapies, as well as the cancer diagnostic value of this scientific information. This book aims to introduce essential aspects of the normal and pathological cellular fate and homeostasis to both scientists and clinicians, and also to provide established researchers with an update on the novelties and future directions this expanding field is witnessing.
Intercellular Communication In Cancer
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Author : Mustapha Kandouz
language : en
Publisher:
Release Date : 2015
Intercellular Communication In Cancer written by Mustapha Kandouz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Cells are by nature compelled to live in groups. They develop dependence over signaling cues received from their microenvironment, in particular from other cells, whether of their own "kind" or of a different type. Therefore, communicating with these cells is a critical aspect of their behavior and fate, as they live and die normally or as they undergo disease-related pathological changes, with dramatic repercussions. In this book, we have asked expert researchers in the field of Intercellular Communication in Cancer to provide chapters on different aspects of interaction between neighboring cells, in the context of cancer diseases. We have specifically focused our efforts on membrane-to-membrane contact-based rather than growth factors-mediated modes of intercellular communications. The contributing authors provide an extensive overview of their respective area of specialization, with an in-depth discussion of the molecular mechanisms of cell-cell interactions, the impact on tumor progression and response to therapies, as well as the cancer diagnostic value of this scientific information. This book aims to introduce essential aspects of the normal and pathological cellular fate and homeostasis to both scientists and clinicians, and also to provide established researchers with an update on the novelties and future directions this expanding field is witnessing.
Emerging Concepts Of Tumor Exosome Mediated Cell Cell Communication
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Author : Huang-Ge Zhang
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-06
Emerging Concepts Of Tumor Exosome Mediated Cell Cell Communication written by Huang-Ge Zhang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-06 with Medical categories.
In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently become the subject of increasing interest: the release of exosomes. In cancer, tumor exosomes are involved in various aspects of pathogenesis, including proliferation, immunosuppression, and metastasis. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. They are also being studied as prognostic markers for cancer.
Intercellular Communication
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Author : Walmor DeMello
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Intercellular Communication written by Walmor DeMello and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Progress made in the last 20 years clearly indicates that the cell surface is an extremely dynamic structure involved in fundamental processes such as cell motility, innervation, and cell adhesion. Of particular interest is the finding that, in several tissues, the cell surface is differen tiated at the intercellular region, thereby providing communicating chan nels between apposing cells. Although our actual knowledge of the precise structures and mecha in the complex process of intercellular communication is still nisms involved scanty, evidence has been presented that ions and molecules diffuse from cell to cell, establishing a physiological continuum. Embryonic differentia tion, cell growth, neoplasia, electrical synchronization in nerve and mus cles, as well as immune response seem to be related to ceIl communication. In organizing this volume, it has been our intention to provide the reader with an actual review of the processes involved in intercellular communication in normal tissues as well as in neoplasia. We sincerely believe that the opinions and experiences described herein will be of help in establishing new perspectives for the future of this exciting new field of cell biology. We wish to thank all the colleagues who joined us in the organization of this volume, as well as Plenum Publishing Corporation for making its appearance possible.
Emerging Concepts Of Tumor Exosome Mediated Cell Cell Communication
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Author :
language : en
Publisher: Springer
Release Date : 2012-09-07
Emerging Concepts Of Tumor Exosome Mediated Cell Cell Communication written by and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-07 with categories.
An Electrophysiological And Scanning Electron Microscopic Investigation Of Intercellular Communication Between Normal And Between Cancer Cells In Tissue Culture
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Author : Paul Harris O'Lague
language : en
Publisher:
Release Date : 1969
An Electrophysiological And Scanning Electron Microscopic Investigation Of Intercellular Communication Between Normal And Between Cancer Cells In Tissue Culture written by Paul Harris O'Lague and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with Cancer cells categories.
Cell Proliferation In Cancer
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Author : Lajos Pusztai
language : en
Publisher:
Release Date : 1996
Cell Proliferation In Cancer written by Lajos Pusztai and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Cancer cells categories.
Research in cellular and molecular biology has reached the point now where it is possible to begin to see how the different fields of cancer genetics/oncogene research and intercellular communication form an integrated molecular model for the regulation of normal and neoplastic cellproliferation. A number of important discoveries in this field during the past few year shave greatly increased our understanding of cancer biology and have offered new diagnostic and prognostic parameters in oncology. This information also holds the promise of novel, more effective therapeuticapproaches to cancer. However, it is becoming increasingly difficult for an individual to maintain a wide and informed knowledge of current concepts in this rapidly moving field, or to form an integrated overview of the myriad factors involved in neoplastic cell proliferation.This book comprises a number of state-of-the-art reviews written by leading scientists. Each chapter gives a concise overview of specific intra-and intercellular events which regulate the proliferation of neoplastic cells, and the established and potential clinical implications of thesedevelopments. The topics have been selected to cover major recent advances in our understanding of the molecular events which govern cell division. It is expected that students, scientists and clinicians working in the fields of oncology, pathology, and molecular/cellular biology would find thisvolume invaluable as a stimulating source of information.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Cell Intercommunication
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Author : Walmore C. De Mello
language : en
Publisher: CRC Press
Release Date : 1989-12-21
Cell Intercommunication written by Walmore C. De Mello and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-12-21 with Science categories.
This important publication addresses intercellular communication in health and disease. It includes recent advances in morphology and chemical organization of gap junctions. It discusses the possible role of intercellular channels in excitable and non-excitable tissues. The book presents modulation of junctional permeability, as well as the possible role of cell communication in embryonic development and growth. The text concludes with a synthetic view of the role of gap junctions and potential implications to cardiology, oncology, and other areas of pathology. This volume is important to professionals in pharmacology, physiology, biochemistry, biomedical science, pathobiology, pathology, molecular genetics, toxicology and human development.
Signal Transduction In Cancer
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Author : David A. Frank
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-12-31
Signal Transduction In Cancer written by David A. Frank and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-31 with Medical categories.
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."