International Congress On Growth Hormone And Somatomedins During Lifespan
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International Congress On Growth Hormone And Somatomedins During Lifespan
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Author : Eugenio E. Müller
language : en
Publisher:
Release Date : 1992
International Congress On Growth Hormone And Somatomedins During Lifespan written by Eugenio E. Müller and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with categories.
Growth Hormone And Somatomedins During Lifespan
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Author : Eugenio E. Müller
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Growth Hormone And Somatomedins During Lifespan written by Eugenio E. Müller and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The various congresses on growth hormone (GH) which have been held in Milan since 1967, the Milan Congresses, have witnessed over 25 years the tremendous expansion of a research field that was based initially upon the scarce knowledge of the biological properties of a protein. GH, whose chemical structure had just been identified and a radioimmunoassay developed for its measurement in blood, became in the following years a major area of biological research. The boundaries have since become blurred, as the research area has extended to the physiology and pathology of growth, puberty and reproduction, and the control of metabolism during the whole lifespan. Since the last GH Congress held in 1987, GH studies using the molecular biological approach have resulted in the puri fication, cloning and expression of the human GH (hGH) recep tor and binding protein, in new and exciting information on the insulin-like growth factors (IGF) and their paracrine and autocrine roles, and in the awareness that a panoply of binding proteins are present in the extracellular fluids and can, possibly, modulate IGF-receptor interactions and, thus, IGF actions. Finally, the availability of large amounts of biosynthetic hGH, besides allow ing more extensive clinical use in states of GH deficiency and extrasomatotrophic pathologies, has permitted disclosure of im portant metabolic effects of hGH during adulthood and, perhaps, aging and in many protein catabolic states.
Fetus And Neonate Physiology And Clinical Applications Volume 3 Growth
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Author : Mark A. Hanson
language : en
Publisher: Cambridge University Press
Release Date : 1995-10-12
Fetus And Neonate Physiology And Clinical Applications Volume 3 Growth written by Mark A. Hanson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-10-12 with Medical categories.
This volume on the growth of the fetus and neonate is introduced with an overview of the physiology and endocrinology of normal growth, before looking in depth at the pathophysiology and clinical applications.Several chapters focus on fetal growth retardation and the challenges this condition poses for the clinician. The measurement and assessment of fetal growth and well being are also fully addressed. Another important theme is the programming of adult diseaes early in the development of the fetus. In summary, this is a stimulating account of an important area of scientific and clinical development.
Aging
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Author :
language : en
Publisher:
Release Date : 1992
Aging written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Aging categories.
Journal Of Endocrinological Investigation
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Author :
language : en
Publisher:
Release Date : 2005
Journal Of Endocrinological Investigation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Endocrinology categories.
Index Of Conference Proceedings
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Author :
language : en
Publisher:
Release Date : 1995
Index Of Conference Proceedings written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Conference proceedings categories.
Neuroendocrinology
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Author :
language : en
Publisher:
Release Date : 1994
Neuroendocrinology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Neuroendocrinology categories.
Growth Hormone Deficiency In Adults
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Author : Jens O. L. Jørgensen
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2005-01-01
Growth Hormone Deficiency In Adults written by Jens O. L. Jørgensen and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-01 with Science categories.
It has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.
Molecular And Clinical Advances In Pituitary Disorders 1993
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Author : Shlomo Melmed
language : en
Publisher: Endocrine Research & Education, Incorporated
Release Date : 1993
Molecular And Clinical Advances In Pituitary Disorders 1993 written by Shlomo Melmed and has been published by Endocrine Research & Education, Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Pituitary gland categories.
Igfs Local Repair And Survival Factors Throughout Life Span
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Author : David Clemmons
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-01
Igfs Local Repair And Survival Factors Throughout Life Span written by David Clemmons and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-01 with Medical categories.
Insulin-like growth factors (IGFs), their binding proteins and their receptors play important roles in regulating growth, metabolism, proliferation and survival for many cells and tissues throughout lifespan in humans and other species. Circulating IGF1 is known to be an endocrine regulator, with metabolic effects related to, and partly convergent with, insulin signalling. IGF1 also mediates many of the growth promoting effects of GH, and there is an ongoing debate as to the relative contributions of endocrine-, vs locally-derived IGF1 for systemic growth. More recently however, it has become clear that IGFs may be key local growth and cellular survival factors for many different tissues, active from early in embryonic development, essential for normal maturation and growth during foetal life. IGFs continue to play important roles throughout adult life in many diverse processes such as tissue repair, cellular proliferation, tissue remodelling and metabolic regulation. IGF systems are tightly regulated; orderly control of cellular repair and metabolism is central to healthy ageing, whilst uncontrolled proliferation can lead to cancer.
