Interplay Between Autophagy And Metabolic Syndrome Causes Consequences And Therapeutic Challenges


Interplay Between Autophagy And Metabolic Syndrome Causes Consequences And Therapeutic Challenges
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Interplay Between Autophagy And Metabolic Syndrome Causes Consequences And Therapeutic Challenges


Interplay Between Autophagy And Metabolic Syndrome Causes Consequences And Therapeutic Challenges
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Author : Joilson O. Martins
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-01

Interplay Between Autophagy And Metabolic Syndrome Causes Consequences And Therapeutic Challenges written by Joilson O. Martins and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-01 with Science categories.




Cross Talk And Interaction Between Endocrinology And Urology Challenges And Opportunities


Cross Talk And Interaction Between Endocrinology And Urology Challenges And Opportunities
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Author : Xiao-qiang Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-22

Cross Talk And Interaction Between Endocrinology And Urology Challenges And Opportunities written by Xiao-qiang Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-22 with Medical categories.


The genitourinary system is closely related to the endocrine system. Some genitourinary organs are endocrine organs themselves. Over the past decades, the diagnosis and treatment on both endocrine and urological diseases have developed rapidly. Concerns regarding the normal growth, development, and physiological functions of the genitourinary system, as well as the pathogenesis and treatment of urinary diseases have been raised. The diseases from these two different systems belong to the specialties of internal medicine and surgery respectively. For example, prostate is regulated by androgen originates from testis, adrenal and even malignancies. Androgen deprivation therapy has definite effect on prostatic adenocarcinoma but may also develop castration resistance. The disorders of gonad and reproductive health are also implicated in hormone regulation, such as delayed hypogonadism. Many diseases such as Cushing's syndrome and aldosteronism are transdisciplinary. However, the research on the normal physiological function, and the comprehensive diagnosis and treatment of both systems are short of cross-integration, resulting in a lack of close cooperation between physicians and surgeons. We are calling for more attention on the joint participation in multidisciplinary diagnosis and treatment, as well as collaboration on basic research in the field of genitourinary and endocrine diseases.



Metabolic Abnormalities And Breast Cancer Challenges From Bench To Bedside


Metabolic Abnormalities And Breast Cancer Challenges From Bench To Bedside
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Author : Xiaosong Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-01

Metabolic Abnormalities And Breast Cancer Challenges From Bench To Bedside written by Xiaosong Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-01 with Medical categories.




Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging


Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging
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Author : M. A. Hayat
language : en
Publisher: Academic Press
Release Date : 2017-09-07

Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging written by M. A. Hayat and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-07 with Medical categories.


Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms. Presents the most advanced information regarding the role of the autophagic system in life and death States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities Summarizes the most up-to-date findings on how autophagy is executed and regulated at the molecular level and how its disruption can lead to disease Authored by global leaders in the field, bringing the broadest, most expert coverage available



Cell Death Signaling In Cancer Biology And Treatment


Cell Death Signaling In Cancer Biology And Treatment
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Author : Daniel Johnson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-19

Cell Death Signaling In Cancer Biology And Treatment written by Daniel Johnson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-19 with Science categories.


A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.



New Drug Targets For Proteotoxicity In Cardiometabolic Diseases


New Drug Targets For Proteotoxicity In Cardiometabolic Diseases
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Author : Jun Ren
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-02

New Drug Targets For Proteotoxicity In Cardiometabolic Diseases written by Jun Ren and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-02 with Science categories.




Metabolic Cardiomyopathy


Metabolic Cardiomyopathy
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Author : H. Böhles
language : en
Publisher: CRC Press
Release Date : 2004

Metabolic Cardiomyopathy written by H. Böhles and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cardiomyopathy categories.


During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.



Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging


Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging
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Author : M. A. Hayat
language : en
Publisher: Academic Press
Release Date : 2016-12-28

Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging written by M. A. Hayat and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-28 with Medical categories.


Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. Presents the most advanced information regarding the role of the autophagic system in life and death Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available



Autophagy And Cardiometabolic Diseases


Autophagy And Cardiometabolic Diseases
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Author : Jun Ren
language : en
Publisher: Academic Press
Release Date : 2018-04-12

Autophagy And Cardiometabolic Diseases written by Jun Ren and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-12 with Medical categories.


Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the delicate role for autophagy in pathogenesis and exploring complications for cardiometabolic diseases. By targeting autophagy, it offers new avenues for drug discovery and treatment for cardiometabolic anomalies. It is a perfect resource for cardiology researchers, scientists and medical practitioners. Explains the processes inherent in the protein quality control for pathogenesis and complications of cardiometabolic diseases Provides knowledge from internationally recognized contributors in the field Incorporates a translational approach, covering the basic cellular biology of autophagy and presenting the role of autophagy regulation for both pathogenesis and complication in cardiometabolic diseases Contains access to a companion website with additional illustrations



The Dynamic Interplay Between Nutrition Autophagy And Cell Metabolism


The Dynamic Interplay Between Nutrition Autophagy And Cell Metabolism
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Author : Vincenzo Flati
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-28

The Dynamic Interplay Between Nutrition Autophagy And Cell Metabolism written by Vincenzo Flati and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-28 with Science categories.