Intestinal Inflammation Implications For Therapeutic Interventions In Ibd
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Intestinal Inflammation Implications For Therapeutic Interventions In Ibd
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Author : Daisy Ross
language : en
Publisher:
Release Date : 2020-09-08
Intestinal Inflammation Implications For Therapeutic Interventions In Ibd written by Daisy Ross and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-08 with Medical categories.
Inflammatory bowel disease refers to diseases which involve the chronic inflammation of the digestive tract. There are primarily two types of inflammatory bowel diseases, namely, ulcerative colitis and Crohn's disease. Ulcerative colitis involves long-lasting inflammation in the innermost lining of the large intestine. Crohn's disease is characterized by the inflammation of the lining of the digestive tract. Some of the symptoms which accompany these diseases are severe diarrhea, weight loss, fatigue and abdominal pain. It is caused by immune malfunction. An abnormal immune response can lead to the immune system attacking the cells in the digestive tract. This book contains some path-breaking studies in the field of inflammatory bowel disease. It elucidates the concepts and innovative models around therapeutic interventions with respect to this disease. This book is appropriate for students seeking detailed information in this area as well as for experts.
Mechanisms Of Intestinal Inflammation
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Author : R. Duchmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-04-30
Mechanisms Of Intestinal Inflammation written by R. Duchmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-30 with Medical categories.
In recent years considerable progress has been achieved in regard to our understanding of the induction and modulation of the immune response in the intestinal mucosa. It is clear that this mucosal immune reaction is predominantly steered by certain T-cell populations, which are characterized by their cytokine secretion profile. Less well known are the conditions under which the uptake and processing of a specific antigen leads to a certain immune response, whether it be protective, tolerant or inflammatory. However, here again distinct progress has been made in our understanding. Equally significant for immune regulation in the gut appears to be so-called innate immunity. Every shift of equilibrium in the highly regulated mucosal immune reaction is accompanied by an inflammatory reaction and destruction of the mucosa. In nearly all cases, this inflammatory response is dependent on the presence of bacterial intestinal flora. This book, the proceedings of Falk Symposium 133 on Mechanisms of Intestinal Inflammation: Implications for Therapeutic Intervention in IBD', held in Berlin, Germany, on 10-11 June 2003, summarizes present knowledge in the area of unspecific and specific immune reactions in the gut, recording the gaps in our knowledge and, in particular, presenting the possibilities of targeted intervention. The link to inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is always in focus. Chapters by an international panel of basic scientists, clinical researchers and clinicians also record the problems which can originate through today's possible modulation of the immune reaction, setting the basis for review of clinical problems. This book is valuable readings for all scientists and physicians, who, from different perspectives, have an interest in research on IBD and in the clinical management of these diseases.
Inflammatory Bowel Disease
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Author : L.R. Sutherland
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Inflammatory Bowel Disease written by L.R. Sutherland and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The inflammatory bowel diseases, of unknown etiology and for which there are no cures, continue to attract the attention and interest of gastroenterologists, internists and surgeons. International symposia are common and it is safe to say that there is at least one major symposium held somewhere in the world each year. This book encompasses the proceedings of two recent symposia held in Victoria, British Columbia, Canada. The symposia were the fifth and sixth international meetings focused on inflammatory bowel disease in Canada in the last eight years. Once again they were sponsored by Axcan Pharma, Inc. (formerly Interfalk Canada, Inc.) and endorsed by the Canadian Association of Gastroenterology. As has become traditional at such meetings the faculty was drawn from an international roster ofleaders in the field of inflammatory bowel disease and gastroenterology. The chapters of the proceedings provide a timely, up-to-date review of the major issues, including those within the realm of basic science and others dealing with clinical problems. The first symposium, 'Basic Research and Clinical Implications', was co-ordinated by John Wallace in association with Stephen Collins and Stephan Targan. The themes of this section were organized under the general topics of predisposing factors (genetics, animal models, infection, permeability, and immune deficits) and the pathophysiology of intestinal inflammation. The second symposium, Trends in Therapy' was organized by Lloyd Sutherland along with Franc;:ois Martin, Robin McLeod and Noel Williams.
Advanced Therapy Of Inflammatory Bowel Disease Volume 2
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Author : Theodore M. Bayless
language : en
Publisher: PMPH-USA
Release Date : 2014-05-14
Advanced Therapy Of Inflammatory Bowel Disease Volume 2 written by Theodore M. Bayless and has been published by PMPH-USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Crohn's disease categories.
Now published in two volumes to accommodate new chapters on the many advances in understanding and treatment options, this set of volumes represents the definitive reference on inflammatory bowel disease, a spectrum of diseases that is receiving increasing attention as our understanding of the etiological factors increases and diagnostic tools are refined. Basic research accelerated at the beginning of this decade and is now yielding new, more targeted treatments than were available just a few years ago. Volume 1 is on IBD and Ulcerative Colitis, and Volume 2 is on IBD and Crohn's Disease. All areas that were covered in the 2nd edition have been expanded and updated. New sections include the rapidly expanding knowledge of genetics and the role of the intestinal flora and environmental factors in etiology and pathogenesis. Among the 168 chapters, there are 20 on biologic therapies and 30 on surgical management. The consultant/authors clearly state their approach to important issues, such as the duration of immunomodulator and of anti-TNF-a use and the options for managing isolated low-grade dysplasia. A strong focus on the individual patient is woven throughout both volumes, including the benefits and risks of potentially life-altering therapies and surgeries. Entire sections detail concerns about the well-being of each person. This book provides information for health professionals who help both pediatric and adult patients navigate through the lifelong shadow of a chronic, probably genetically determined ordeal.
Nutrition In Inflammatory Bowel Disease Ibd
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Author : Maitreyi Raman
language : en
Publisher: MDPI
Release Date : 2019-09-02
Nutrition In Inflammatory Bowel Disease Ibd written by Maitreyi Raman and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-02 with Health & Fitness categories.
The purpose of this Special Issue “Nutrition in Inflammatory Bowel Disease (IBD)” is to increase knowledge regarding the role of dietary composition and effects in IBD, describing the prevalence of malnutrition in IBD and the effect on clinical outcomes, discussing methods of nutrition risk screening and assessment in IBD, and reviewing mechanisms through which diet and dietary components may affect disease severity. The articles focus on the following areas: Dietary Composition/Therapy Interventions in Ulcerative Colitis and effects on outcomes; Dietary Composition/Therapy Interventions in Crohn’s Disease and effects on outcomes; Nutrition Risk Screening and Assessment in IBD; Mechanisms of Diet in the pathogenesis of IBD.
Inflammatory Bowel Disease
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Author : Russell D. Cohen
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-03-12
Inflammatory Bowel Disease written by Russell D. Cohen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-12 with Medical categories.
One of the most vivid memories from my medical school training was seeing my first surgical operation on a patient with Crohn’s disease. The senior surgeon at Mount Sinai Hospital in New York City, the same institution at which Burrill Crohn, Leon Ginzburg, and Gordon Oppenheimer had first described the disease “terminal ileitis,” had - doubtedly done countless operations on patients with inflammatory bowel disease in the past. Yet as we both gazed down into the patient’s open abdomen, at the “creeping fat” that seemed to be wrapping its sticky fingers around the young man’s intestines, he stated, “this is the m- tery of Crohn’s disease—no two patients are ever the same. ” What is it about the inflammatory bowel diseases, Crohn’s disease, and ulcerative colitis, that we find so intriguing? Is it the young age of the patients, many who are younger than even the medical students - tending to them? Or is it the elusive etiology, the theory of a “mystery organism” that has yet to be identified? Perhaps it is the familial pattern of disease, where many patients have relatives with similar diseases, yet in some instances only one of a pair of identical twins is affected. Regardless of the cause, these chronic diseases with a typically early age of onset, result in a long-term commitment of the patient, their fa- lies, friends, health care providers, researchers, employers, and even health care insurers and other health-related industries.
Inflammatory Bowel Disease
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Author : Stephan R. Targan
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24
Inflammatory Bowel Disease written by Stephan R. Targan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Medical categories.
This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.
Pediatric And Inflammatory Bowel Disease
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Author : John A. Walker-Smith
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2009
Pediatric And Inflammatory Bowel Disease written by John A. Walker-Smith and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.
Chronic inflammatory bowel disease (IBD) encompasses Crohn's disease, ulcerative colitis and indeterminate colitis. The distinct phenotype in pediatric and adolescent patients and the difference from adult IBD make early-onset IBD a unique subgroup requiring specific therapeutic considerations. In this book, leading experts from the USA, Europe and Israel present new data on the genetics, epidemiology, pathology and pathogenesis of pediatric IBD. Imaging and endoscopy in the diagnosis of IBD are also discussed. Extensive coverage is given to disease management, i.e. pharmacological, nutritional and surgical approaches, with special emphasis on growth failure and delayed puberty. The important topic of transition from pediatric to adult medical care is highlighted and a clinical and developmental timeline is proposed.Offering practical information on IBD in infants, toddlers, children, adolescents and young adults, this book is essential reading for gastroenterologists, in particular pediatric gastroenterologists and trainees, as well as general pediatricians and nutritionists.
Gastrointestinal Inflammation And Disturbed Gut Function The Challenge Of New Concepts
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Author : G. Holtmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-09-30
Gastrointestinal Inflammation And Disturbed Gut Function The Challenge Of New Concepts written by G. Holtmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-30 with Medical categories.
This book, the proceedings of Falk Symposium 130 on 'Gastrointestinal Inflammation and Disturbed Gut Function: The Challenge of New Concepts', held in Freiburg, Germany, on October 4-6, 2002 (Part I of the Gastroenterology Week Freiburg 2002), reviews ground-breaking work and will stimulate new research in the functional GI disorders, from the bench to the bedside. Basic scientists, clinical researchers and clinicians interested in this field explore controversial and exciting areas of research, and consider targets for future therapeutic interventions.
Inflammatory Bowel Disease
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Author : Russell D. Cohen
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-03-22
Inflammatory Bowel Disease written by Russell D. Cohen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-22 with Medical categories.
As in the first edition of Inflammatory Bowel Diseases this new edition continues to provide readers with a concise, yet in-depth review of many of the important areas in the history, epidemiology, pathogenesis, diagnosis, and treatment of the inflammatory bowel diseases (ulcerative colitis and Crohn's disease), as well as associated issues: extraintestinal manifestations, ostomy care, women's issues, economics, etc. This Second Edition provides the reders with up-to-date, state-of-the art approaches to these disease states, with expansion into the newer topics that have emerged in the past few years which include the expansion of biological agents for treatment, new studies in the epidemiology of IBD, the changing economics of IBD, breakthroughs in new endoscopic evaluations, major advances in novel radiographic techniques, the detection of colorectal cancer in patients with IBD and new findings in the genetics of IBD. New Trend / Developments (* These all emerged since our last edition) The most critical trend that has arisen over the past few years has been the introduction and expansion of biological agents in the treatment of inflammatory diseases worldwide. While only one agent, infliximab (Remicade), existed at the time of publication of my first edition, there have been multiple other agents either approved or pending approval for the treatments of these diseases, or in the upper-stages of development. The impact is not only upon the patients, but also on the health-care providers, policy makers, researchers, biotech and pharmacompanies, and the business community. Major changes worldwide in the epidemiology of IBD has spurred new studies in the demographics of who is getting these diseases and why. Previously characterized as diseases primarily affected Caucasians in industrialized countries, there has been an explosion of growth amongst the African American and Hispanic populations in the United States, and well as in pockets of these and other ethnic groups worldwide. The economics of IBD has been changing greatly, given the issues raised above, as well as major changes in the United States Medicare program, and other insurance changes. The growing proportion of the GNP that healthcare costs are consuming in the US and worldwide has shifted attention to decreasing utilization of health care services, and other cost-savings measures. Again, up to this point this has been an exclusive part of our IBD book. New findings in the genetics of IBD have been recently published. Our first edition had the finding of the first Crohn’s disease gene inserted just before going to press; so much has been published about the phenotypes and other genotypes that have emerged. Breakthroughs in new endoscopic evaluations of the bowel (ie. Capsule endoscopy, double-balloon enteroscopy, endoscopic ultrasound) and their use in the inflammatory bowel diseases will be a key highlight of this new book. Major advances in novel radiographic techniques employed in patients with inflammatory bowel disease (ie. CT enterography, MR enterography, advanced ultrasounds, etc.) will also an important component of our work. There have been numerous areas related to the development and detection of colorectal cancer in patients with IBD that have emerged in the past few years. Techniques of better detection (ie. Narrow band imaging; special mucosal staining; endoscopic histological evaluations) as well as research in the putative role of mesalamine and other agents for colorectal cancer prevention are all hot topics that will attract much interest from a variety of interest groups I described above. Identification of additional disease states that probably belong in the IBD family, such as microscopic colitis (including lymphocytic colitis), and collagenous colitis add to the diseases that will be discussed in this new edition.