Investigative Immunotoxicology
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Investigative Immunotoxicology
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Author : Helen Tryphonas
language : en
Publisher: CRC Press
Release Date : 2005-01-27
Investigative Immunotoxicology written by Helen Tryphonas and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-27 with Medical categories.
Investigative Immunotoxicology provides a critical evaluation of proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity can make to the overall assessment of chemical-induced adverse health effects on humans and the ecosystem. Following a review of general concepts in immunotoxicology, the book discus
Investigative Immunotoxicology
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Author : Helen Tryphonas
language : en
Publisher: CRC Press
Release Date : 2005-01-27
Investigative Immunotoxicology written by Helen Tryphonas and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-27 with Medical categories.
Investigative Immunotoxicology provides a critical evaluation of proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity can make to the overall assessment of chemical-induced adverse health effects on humans and the ecosystem. Following a review of general concepts in immunotoxicology, the book discus
Immunotoxicology Strategies For Pharmaceutical Safety Assessment
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Author : Danuta J. Herzyk
language : en
Publisher: John Wiley & Sons
Release Date : 2008-11-21
Immunotoxicology Strategies For Pharmaceutical Safety Assessment written by Danuta J. Herzyk and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-21 with Medical categories.
An important reference which provides an overview of the current and recently introduced methodologies for testing the immunotoxic risks in drug candidates Helps readers understand the significance of the methods and approaches to immunotoxicology testing Aids drug scientists in industry and regulatory areas to consolidate approaches to immunotox testing Offers a definitive assessment of nonclinical models to study the toxic impacts (bio)pharmaceuticals can have on the immune system Includes chapter authors from across the pharma industry, bringing a real-world and applied perspective to immunotox testing
Molecular Immunotoxicology
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Author : Emanuela Corsini
language : en
Publisher: John Wiley & Sons
Release Date : 2014-11-24
Molecular Immunotoxicology written by Emanuela Corsini and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-24 with Science categories.
The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be considered. Following an introduction to the various pathways and toxicity mechanisms from a systemic perspective, the main part of this comprehensive reference surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity, using analyses based on molecular effects rather than on animal models. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.
Immunotoxicology And Immunopharmacology
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Author : H Dean Jack
language : en
Publisher: CRC Press
Release Date : 1994-06-30
Immunotoxicology And Immunopharmacology written by H Dean Jack and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-06-30 with Medical categories.
The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.
T Lymphocytes Subpopulations In Immunotoxicology
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Author : Ian Kimber
language : en
Publisher: John Wiley & Sons
Release Date : 1998-08-17
T Lymphocytes Subpopulations In Immunotoxicology written by Ian Kimber and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-17 with Science categories.
Den T-Lymphocyten kommt eine Schlüsselrolle im Immunsystem zu: Sie sind unter anderem für Resistenzen gegenüber Infektionen und Tumoren und für die Entwicklung von Allergien und Autoimmunität verantwortlich. Bisher gab es kein vergleichbares Buch, das Funktionen und Subpopulationen der T-Zellen wie das vorliegende Werk von immunbiologischen Grundlagen ausgehend zusammenfassend darstellt.(05/98)
An Investigation Of The Immunotoxicology Of Chromium Nickel And Barium From Inhaled Metal Fumes
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Author : L. Q. A. Caldas
language : en
Publisher:
Release Date : 1986
An Investigation Of The Immunotoxicology Of Chromium Nickel And Barium From Inhaled Metal Fumes written by L. Q. A. Caldas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with categories.
Cytokines In Human Health
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Author : Robert V. House
language : en
Publisher: Humana Press
Release Date : 2007-04-23
Cytokines In Human Health written by Robert V. House and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-23 with Medical categories.
This comprehensive book explores the role of cytokines in immunotoxicology and human health using a variety of complex methods, from basic research to highly applied therapeutic applications. It includes a basic study of cytokines and details the effects of cytokines on the immune system and in treating cancer. The book serves as both a primer and a starting point for a more detailed investigation of the role these biological regulators play.
Clinical Immunotoxicology
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Author : David S Newcombe
language : en
Publisher: CRC Press
Release Date : 1992-06-30
Clinical Immunotoxicology written by David S Newcombe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-06-30 with Medical categories.
This text is a comprehensive source of information on the toxic effects of environmental, industrial, and pharmacological agents on the human immune system. Focusing entirely on human immunotoxicology, without relying on animal models, the book explains the basic principles of immunotoxicology defines the mechanisms by which immunotoxins act, describes the clinical expression of immunotoxic disorders in the lung, skin, and other target organs, offers practical guidelines for early detection and control of host defense dysfunctions, and explores strategies for assessing the short- and long-term health effects of new and old chemicals and biologicals. The book includes extensive discussions on the role of low-dose, chronic immunosuppression in cancer, as well as on specific environmental and occupational immunotoxins and immunotoxic drugs used in hematology, anesthesiology, oncology and transplantation surgery.
History Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Academic Press
Release Date : 2019-04-15
History Of Immunotoxicology written by Jacques Descotes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Medical categories.
History of Immunotoxicology offers the first book-length exploration of the development and importance of the field of immunotoxicology, describing the adverse health effects involving the immune system, hypersensitivity and autoimmunity. It explores new avenues of research and immunotoxicity evaluation, regulatory aspects of immunotoxicology, and the withdrawal/banning from the market of several approved drugs and chemicals due to their immunotoxic effects. In addition, clinical manifestations of immunotoxicity, such as anaphylaxis, opportunistic infections, lymphomas, cytokine storm, and immunotherapy are addressed. Finally, the book considers how the recent past can provide insights on the future practice of immunotoxicology. As preventive measures are implemented to reduce risks, including banning of chemicals or applications of one given chemical, current toxicologists may not be aware of the toxicity potential of chemicals. This book will be of interest to students and researchers in government, industry and academia who have an interest in immunotoxicology. Examines the development of immunotoxicology Provides context to current debates on the actual toxicity potential of chemicals Covers major developments and areas of immunotoxicology