Ionizing Radiation Reprograms Tumor Immune Microenvironment By Inducing Immunogenic Cell Death
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Ionizing Radiation Reprograms Tumor Immune Microenvironment By Inducing Immunogenic Cell Death
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Author : Fei Yu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-25
Ionizing Radiation Reprograms Tumor Immune Microenvironment By Inducing Immunogenic Cell Death written by Fei Yu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-25 with Medical categories.
Role Of Radiotherapy In The Era Of Targeted Therapy And Precision Oncology
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Author : Kevin X. Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-03
Role Of Radiotherapy In The Era Of Targeted Therapy And Precision Oncology written by Kevin X. Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-03 with Medical categories.
Multidisciplinary Management Of Head And Neck Cancer
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Author : Ravi A. Chandra
language : en
Publisher: Springer Nature
Release Date : 2022-09-09
Multidisciplinary Management Of Head And Neck Cancer written by Ravi A. Chandra and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-09 with Medical categories.
This book is a multidisciplinary guide to head and neck cancer.Head and neck cancer remains one of the most technically complex cancer subsites to manage. This field involves highly specialized, multidisciplinary management and collaboration amongst surgeons, radiation oncologists, medical oncologists, radiologists, pathologists, and other health disciplines. The clinical and research landscape for head and neck oncology continues to evolve at a rapid pace. This multidisciplinary book provides the latest updates in the contemporary understanding and management of these tumors. The text incorporates updates in surgical techniques (minimally invasive and robotic techniques, reconstructive approaches), radiation medicine (new data on dose and fields, oligometastatic/oligoprogressive disease, retreatment), medical oncology (targeted, immunotherapy and molecular agents), in addition to other overarching topics such as side effects, biomarkers/nanotechnology, and epidemiology. Written by experts in their respective fields, chapters include the most up to date scientific and clinical information with perspectives from each relevant subspeciality. These sections are concise and accessible, yet comprehensive. Palliative medicine, pathologic and imaging principles, and health systems/economics considerations are also described. This book is an ideal resource for clinicians, trainees, and researchers dealing with, and interested in, this challenging malignancy.
The Role Of The Tumor Microenvironment Tme And Relevant Novel Biomarkers In Oncogenesis
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Author : Zhouxiao Li
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-15
The Role Of The Tumor Microenvironment Tme And Relevant Novel Biomarkers In Oncogenesis written by Zhouxiao Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-15 with Science categories.
Oncothermia Principles And Practices
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Author : Andras Szasz
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-23
Oncothermia Principles And Practices written by Andras Szasz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-23 with Medical categories.
Oncothermia is the next generation medical innovation that delivers selective, controlled and deep energy for cancer treatment. The basic principles for oncothermia stem from oncological hyperthermia, the oldest approach to treating cancer. Nevertheless, hyperthermia has been wrought with significant controversy, mostly stemming from shortcomings of controlled energy delivery. Oncothermia has been able to overcome these insufficiencies and prove to be a controlled, safe and efficacious treatment option. This book is the first attempt to elucidate the theory and practice of oncothermia, based on rigorous mathematical and biophysical analysis, not centered on the temperature increase. It is supported by numerous in-vitro and in-vivo findings and twenty years of clinical experience. This book will help scientists, researchers and medical practitioners in understanding the scientific and conceptual underpinnings of oncothermia and will add another valuable tool in the fight against cancer. Professor Andras Szasz is the inventor of oncothermia and the Head of St Istvan University's Biotechnics Department in Hungary. He has published over 300 papers and lectured at various universities around the world. Dr. Oliver Szasz is the managing director of Oncotherm, the global manufacturer and distributor of medical devices for cancer treatment used in Europe & Asia since the late 1980s. Dr. Nora Szasz is currently a management consultant in healthcare for McKinsey & Co.
Advanced Healthcare Materials
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Author : Ashutosh Tiwari
language : en
Publisher: John Wiley & Sons
Release Date : 2014-05-09
Advanced Healthcare Materials written by Ashutosh Tiwari and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-09 with Technology & Engineering categories.
Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers
Radiation And The Immune System Current Knowledge And Future Perspectives
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Author : Katalin Lumniczky
language : en
Publisher: Frontiers Media SA
Release Date : 2018-05-03
Radiation And The Immune System Current Knowledge And Future Perspectives written by Katalin Lumniczky and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-03 with categories.
For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.
Ionizing Radiation And The Immune Response Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-07-10
Ionizing Radiation And The Immune Response Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-10 with Science categories.
Ionizing Radiation and the Immune Response, Part B, Volume 378 reviews the latest knowledge on the immune response induced by ionizing radiations. Specific chapters in this new release include NK functions in radio-induced immune response, TRT and immune response, Radio-induced immune response and lipid metabolism, Effect of protons and heavy ions on immune response, Effect of flash therapy and mini beam on immune response, Radio-induced lymphopenia, CT to potentiate radio-induced immune response, Impact of RT on healthy tissues (inflammation), Radio-induced macrophagic response, To use nanoparticles and ionizing radiations to modulate immune response: opinion of the chemist, biologist and clinician, and much more. Other sections cover the Role of Dendritic cells in radiation-induced immune response, the Relationship between the tumor microenvironment and the efficacy of the radiotherapy/immunotherapy combination, and Biomarkers of radiation induced response to optimize radio-immunotherapy combination. Covers the latest insights about the biological parameters modulating radio-induced immune response Provides an accurate review by selected experts of the impact on the immune response of radio-enhancer nanoparticles or chemotherapy targeting immunosuppressive immune cells Presents valuable information to clinicians to optimize radiotherapy and immunotherapy combinations
Advances In Radiation Oncology
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Author : Jeffrey Y.C. Wong
language : en
Publisher: Springer
Release Date : 2017-04-20
Advances In Radiation Oncology written by Jeffrey Y.C. Wong and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-20 with Medical categories.
This book concisely reviews important advances in radiation oncology, providing practicing radiation oncologists with a fundamental understanding of each topic and an appreciation of its significance for the future of radiation oncology. It explores in detail the impact of newer imaging modalities, such as multiparametric magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodeoxyglucose (FDG) and other novel agents, which deliver improved visualization of the physiologic and phenotypic features of a given cancer, helping oncologists to provide more targeted radiotherapy and assess the response. Due consideration is also given to how advanced technologies for radiation therapy delivery have created new treatment options for patients with localized and metastatic disease, highlighting the increasingly important role of image-guided radiotherapy in treating systemic and oligometastatic disease. Further topics include the potential value of radiotherapy in enhancing immunotherapy thanks to the broader immune-stimulatory effects, how cancer stem cells and the tumor microenvironment influence response, and the application of mathematical and systems biology methods to radiotherapy.
Radiation Oncology
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Author : Frederik Wenz
language : en
Publisher: Springer
Release Date : 2023-08-29
Radiation Oncology written by Frederik Wenz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-29 with Medical categories.
In this Handbook, a team of leading experts provide a comprehensive and up-to-date overview of the ever-changing field of radiation oncology. The publication is divided into three volumes, the first of which covers basics such as radiotherapy techniques, treatment documentation, clinical radiobiology, and patient management. In the second volume, all aspects of clinical radiation therapy are discussed in depth for the full range of tumor types. In order to ensure that the reader has a full understanding of cancer management in each scenario, information is also provided on diagnosis and classification, general management principles, the role of surgical and systemic therapy, and prognosis. The third volume focuses on medical physics, covering the mathematical and computer science background, biophysics, radiation physics, instrumentation, tracer kinetic modeling, pharmacokinetics and pharmacodynamics, radiation sources and detectors, biomedical engineering, imaging techniques, radiation treatment planning, and quality assurance. This book will be invaluable for all radiation oncologists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.