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Ipscs State Of The Science


Ipscs State Of The Science
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Ipscs State Of The Science


Ipscs State Of The Science
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Author : Alexander Birbrair
language : en
Publisher: Academic Press
Release Date : 2022-01-09

Ipscs State Of The Science written by Alexander Birbrair and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-09 with Science categories.


iPSCs - State of the Science, Volume Sixteen, the latest release in the Advances in Stem Cell Biology series, is an expansive collection of information and new discoveries in the field. This volume addresses the importance of induced pluripotent stems cells and how can they be derived from different sources. It addresses advances in research in induced pluripotent stem cells from alternate sources, such as spermatogonial stem cells, ovarian tissue, cancer cells, and many other sources. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors. - Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics - Covers iPSCs derived from amniotic fluid, oral tissue derived iPSCs, muse cells, postmortem tissue, and much more - Contributed by world-renowned experts in the field



Ipscs State Of The Science


Ipscs State Of The Science
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Author : Alexander Birbrair
language : en
Publisher: Elsevier
Release Date : 2022-01-19

Ipscs State Of The Science written by Alexander Birbrair and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-19 with Science categories.


"[A]ddresses the progress in induced pluripotent stem cell technologies. Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes different technologies and strategies to use induced pluripotent stem cells for biological and clinical benefit. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues, and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; and is contributed by world-renowned authors in the field"--Page 4 of cover.



Scientific Information Bulletin


Scientific Information Bulletin
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Author :
language : en
Publisher:
Release Date : 1993

Scientific Information Bulletin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Research categories.




Phenotyping Of Human Ipsc Derived Neurons


Phenotyping Of Human Ipsc Derived Neurons
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Author : Elizabeth D. Buttermore
language : en
Publisher: Academic Press
Release Date : 2022-09-09

Phenotyping Of Human Ipsc Derived Neurons written by Elizabeth D. Buttermore and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-09 with Medical categories.


Phenotyping of Human iPSC-derived Neurons: Patient-Driven Research examines the steps in a preclinical pipeline that utilizes iPSC-derived neuronal technology to better understand neurological disorders and identify novel therapeutics, also providing considerations and best practices. By presenting example projects that identify phenotypes and mechanisms relevant to autism spectrum disorder and epilepsy, this book allows readers to understand what considerations are important to assess at the start of project design. Sections address reproducibility issues and advances in technology at each stage of the pipeline and provide suggestions for improvement. From patient sample collection and proper controls to neuronal differentiation, phenotyping, screening, and considerations for moving to the clinic, these detailed descriptions of each stage of the pipeline will help everyone, regardless of stage in the pipeline. In recent years, drug discovery in the neurosciences has struggled to identify novel therapeutics for patients with varying indications, including epilepsy, chronic pain, and psychosis. Current treatment options for such patients are decades old and offer little relief with many side effects. One explanation for this lull in novel therapeutics is a lack of novel target identification for neurological disorders (and target identification requires exemplar preclinical data). To improve on the preclinical work that often relies on rodent modeling, the field has begun utilizing patient-derived induced pluripotent stem cells (iPSCs) to differentiate neurons in vitro for preclinical characterization of neurological disease and target identification. - Discusses techniques and new technology for iPSC culturing and neuronal differentiation to establish best practices in the lab - Outlines considerations for phenotypic assay development - Provides information about the successes, failures, and implications of phenotyping and screening with iPSC-derived neurons - Describes how human iPSC-derived neurons are being used for preclinical discovery research as well as the development of therapeutics utilizing hiPSC-derived neurons



Human Induced Pluripotent Stem Cells


Human Induced Pluripotent Stem Cells
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Author : Baojin Ding
language : en
Publisher: Springer Nature
Release Date : 2024-07-13

Human Induced Pluripotent Stem Cells written by Baojin Ding and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-13 with Science categories.


This volume explores the latest developments in the field and showcases the vast potential of human induced pluripotent stem cells (hiPSCs) in advancing neuroscience research. The chapters in this book are organized into three parts. Part One describes the generation, characterization, and validation of hiPSCs using different methodologies from various resources. Part Two focuses on techniques for genome editing of hiPSCs. Part Three covers various hiPSC applications in neuroscience research and strategies for analyzing hiPSC-based model systems. These applications include the generation of neural subtypes, glial cells, and skeletal muscles; assembling co-culture systems to prepare highly pure neurons at late maturation stages; measuring nuclear transport of proteins and transcripts in cultured neurons; and generating brain organoids. In the Neuromethods series style, chapters include the kind of detail and key advice from specialists needed to achieve successful results in your laboratory. Cutting-edge and comprehensive, Human Induced Pluripotent Stem Cells is a valuable resource for researchers and students in neuroscience, neurology, stem cell biology, and other related fields.



Current Progress In Ipsc Disease Modeling


Current Progress In Ipsc Disease Modeling
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Author : Alexander Birbrair
language : en
Publisher: Academic Press
Release Date : 2021-11-11

Current Progress In Ipsc Disease Modeling written by Alexander Birbrair and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-11 with Science categories.


Current Progress in iPSC Disease Modeling, Volume Fourteen in the Advances in Stem Cell Biology series, is a timely and expansive collection of information and new discoveries in the field. This new volume addresses advances in research on how induced pluripotent stem cells are used for the creation of new tissues and organs. The creation of iPSC technology allowed the development of disease-specific human pluripotent stem cells. These cells allow researchers to study questions once impossible for some human diseases. This volume addresses iPSCs for vascular tissue engineering, bioprinting, derived lung organoids for pulmonary disorders, skeletal muscle engineering, human kidney organoids, and more. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. - Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics - Covers advances in research on how induced pluripotent stem cells are used to create new tissues/organs - Contributed by world-renowned experts in the field



Pluripotent Stem Cells Advances In Research And Application 2013 Edition


Pluripotent Stem Cells Advances In Research And Application 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-06-21

Pluripotent Stem Cells Advances In Research And Application 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-21 with Science categories.


Pluripotent Stem Cells—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Pluripotent Stem Cells—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Pluripotent Stem Cells—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Practical Design And Applications Of Medical Devices


Practical Design And Applications Of Medical Devices
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Author : Dilber Uzun Ozsahin
language : en
Publisher: Elsevier
Release Date : 2023-11-25

Practical Design And Applications Of Medical Devices written by Dilber Uzun Ozsahin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-25 with Computers categories.


Practical Design and Applications of Medical Devices focuses on advanced medical device development featuring various biomedical instruments and their applications. The book focuses on devices which receive and transmit bioelectric signals, such as electrocardiograph, electrodes, blood flow, blood pressure, physiological effects and, in some cases, current flowing through the human body. A thorough guide for researchers and engineers in the field of biomedical and instrumentation engineering, this book presents a streamlined medical strategy for designing these medical devices, sensors, and tools. It also promotes operational efficiency in the healthcare industry, with the goals of improving patient safety, lowering overall healthcare costs, broadening access to healthcare services, and improving accessibility. - Covers the fundamental principles of medical and biological instrumentation, as well as the typical features of its design and construction - Provides various methods of designing modern medical devices - Focuses on specific devices with detailed functions, applications, and how they measure and transmit data



Epigenetics In Human Disease


Epigenetics In Human Disease
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Author : Trygve Tollefsbol
language : en
Publisher: Academic Press
Release Date : 2012-07-26

Epigenetics In Human Disease written by Trygve Tollefsbol and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-26 with Medical categories.


Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs



Methods In Ipsc Technology


Methods In Ipsc Technology
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Author : Alexander Birbrair
language : en
Publisher: Academic Press
Release Date : 2021-06-02

Methods In Ipsc Technology written by Alexander Birbrair and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-02 with Science categories.


The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Methods in iPSC Technology, Volume 9 addresses the different methods used for induced pluripotent stem cell (iPSC) formation, maintenance, expansion, and differentiation. The ability to reprogram different cell types to iPSCs offers an opportunity to generate pluripotent patient-specific cell lines that can help in the understanding of multiple human disorders. This volume addresses a variety of current methods used in the generation and manipulation of iPSCs, such as magnetic nanoparticles, piggyBac vectors, lentiviral vectors, bioscaffolds, somatic cell nuclear transfer, CRISPR/Cas9, bacteria, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field. - Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine, and therapeutics - Covers the different methods used for iPSC formation, maintenance, expansion, and differentiation - Is contributed by world-renowned experts in the field