Iron Metabolism
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Iron Metabolism In Health And Disease
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Author : Jeremy H. Brock
language : en
Publisher: Bailliere Tindall Limited
Release Date : 1994
Iron Metabolism In Health And Disease written by Jeremy H. Brock and has been published by Bailliere Tindall Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Ferritin categories.
An overview of human iron metabolism. This book reviews the metabolic importance of iron in evolution, the physiology and biochemistry of internal iron exchange, iron absorption and iron storage, the molecular regulation of cellular iron homeostasis and aspects of iron and disease.
Iron Metabolism
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Author : Robert Crichton
language : en
Publisher: John Wiley & Sons
Release Date : 2016-03-30
Iron Metabolism written by Robert Crichton and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-30 with Medical categories.
Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.
Iron Metabolism
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Author : Ivan Bernat
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Iron Metabolism written by Ivan Bernat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Iron Metabolism
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Author : Franz Gross
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Iron Metabolism written by Franz Gross and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
International Symposia sponsored by ClBA Basle have been held once a year since 1959 in various European countries. In con trast to the many scientific meetings organised by the ClBA FOUN DATION either at its headquarters in London or occasionally abroad, the subjects dealt with at these International Symposia have con cerned problems more directly related to ClBA'S own research work in the pharmaceutical field. The various topics covered up to the present reflect the far-reaching interests and the wide spread activities that a pharmaceutical enterprise develops in quite diverse fields of chemical, biological, and medical research, and to which the ba.sic approach is an increasingly important prerequisite for the development of a new and useful therapeutic agent. Iron metabolism came into the sphere of interest in connection with CIBA'S research on antibiotics and related natural products containing iron, substances which act in their metal-free form as strong and specific chelating agents. Of course, these observations, interesting though they are, would not in themselves have justi fied a symposium. It seemed, however, useful to examine the new results from a wider perspective and to attempt to relate them to present-day knowledge of iron metabolism in general its physiology, its pathology, and therapeutic aspects. The success of a scientific symposium depends on the concep tion of the programme and the selection of the participants.
Iron Metabolism
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Author : Manfred Wick
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Iron Metabolism written by Manfred Wick and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Disturbances of iron metabolism, particularly iron deficiency, are among the most commonly overlooked or misinterpreted diseases. This is due to the fact that the determination of transport iron in serum or plasma, which used to be the test in conventional diagnosis, does not allow a representative estimate of the body’s total iron reserves. A proper estimate was formerly possible only by the costly and invasive determination of storage iron in the bone marrow, however, sensitive, well-standardized immuno-chemical methods for the precise determination of the iron storage protein ferritin in plasma are now available. Since the secretion of this protein correctly reflects the iron stores in the majority of cases, these methods permit fast and reliable diagnosis, particularly of iron deficiency conditions. The fact that iron deficiency is so common and is usually simple to treat ought to be well known in the medical world. Even non-iron-determined causes of anemia can now be identified rapidly by highly sensitive, well standardized immuno-chemical methods. This book is intended to contribute to a better understanding of the main pathophysiological foundations and diagnostic principles.
Iron Metabolism
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Author : Ciba Foundation
language : en
Publisher:
Release Date : 1977
Iron Metabolism written by Ciba Foundation and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Iron categories.
Iron Metabolism
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2022-10-05
Iron Metabolism written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-05 with Science categories.
Iron is an essential element for numerous fundamental biologic processes. Iron-containing proteins are required for vital cellular and organismal functions including oxygen transport, mitochondrial respiration, intermediary and xenobiotic metabolism, nucleic acid replication and repair, host defense, and cell signaling. However, excess iron is toxic. This book provides a comprehensive overview of the essential role of iron in biology, the regulation of systemic and cellular iron homeostasis, and how imbalances in iron homeostasis contribute to disease.
Iron Metabolism
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Author : Robert Crichton
language : en
Publisher: John Wiley & Sons
Release Date : 2016-05-31
Iron Metabolism written by Robert Crichton and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-31 with Medical categories.
Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.
Brain Iron Metabolism And Cns Diseases
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Author : Yan-Zhong Chang
language : en
Publisher: Springer Nature
Release Date : 2019-08-27
Brain Iron Metabolism And Cns Diseases written by Yan-Zhong Chang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-27 with Medical categories.
This book focuses on advances in our understanding of the regulatory mechanisms of brain iron uptake, iron homeostasis and iron metabolism in the pathophysiology and pharmacology of CNS disease models. Dysregulation of brain iron homeostasis can lead to severe pathological changes in the neural system. Iron deficiency can slow down the development of the neural system and cause language and motion disorders, while iron overload is closely related to neurodegenerative diseases. Although some current books include chapters on iron metabolism and certain neurodegenerative diseases, this is the first systematic summary of the latest discoveries regarding brain iron metabolism and CNS diseases. By providing novel and thought-provoking insights into the mechanisms and physiological significance of brain iron metabolism and related diseases, the book stimulates further new research directions. It helps graduate students and researchers gain an overall picture of brain iron metabolism and the pathogenesis of neurodegenerative diseases, and also offers pharmaceutical companies inspiration for new treatment strategies for CNS diseases.
Iron Metabolism In Infants
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Author : Bo Lonnerdal
language : en
Publisher: CRC Press
Release Date : 2020-10-07
Iron Metabolism In Infants written by Bo Lonnerdal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-07 with Medical categories.
There is a critical need for iron intake during the first period of life. The growing infant requires iron to synthesize hemoglobin and to supply expanding tissues with iron-containing enzymes. A lack of iron will eventually lead to iron deficiency anemia, one of the most common single nutrient deficiencies in the world. Today, detailed information has increased our understanding of iron bioavailability from different dietary sources, uptake mechanisms of iron into the small intestinal mucosa for transport to hepatocytes and erythropoietic cells and subsequent receptor mediated cellular acquisition. Metabolic effects of iron deficiency have also been investigated in several tissues. This comprehensive text integrates recent information and address it from a nutritional perspective. It takes this focus because of the increased knowledge on the interrelationship between iron and other essential nutrients. Specific problems of iron nutriture and oxidant stress in prematurely born infants are also addressed in this informative new text