Ketamine For Treatment Resistant Depression
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Ketamine For Treatment Resistant Depression
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Author : Sanjay J. Mathew
language : en
Publisher: Springer
Release Date : 2016-11-25
Ketamine For Treatment Resistant Depression written by Sanjay J. Mathew and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-25 with Medical categories.
This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research.
Ketamine For Treatment Resistant Depression
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Author : Gustavo H. Vazquez
language : en
Publisher: Academic Press
Release Date : 2020-09-16
Ketamine For Treatment Resistant Depression written by Gustavo H. Vazquez and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-16 with Medical categories.
Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. Provides efficacy research on ketamine as a treatment for depression Identifies best practices for clinical use, both long-term and acute Discusses the molecular mechanisms and neurobiology of action
Ketamine For Depression
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Author : Dr. Stephen J. Hyde
language : en
Publisher: Xlibris Corporation
Release Date : 2015-09-04
Ketamine For Depression written by Dr. Stephen J. Hyde and has been published by Xlibris Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-04 with Health & Fitness categories.
Given the unacceptably high rates of suffering, disability and premature death experienced by people with treatment-resistant depression and the surprisingly low rates of problems arising from the use of ketamine to treat the disorder, this is a therapy that all patients and their doctors should be discussing. This book summarises the research that has been carried out into ketamine for the treatment of depression over the past 15 years and, most importantly, describes different ways of using ketamine that are both practical and cost–effective. Currently most ketamine therapy is given intravenously in specialised clinics at considerable expense, but the author has successfully treated patients with low-dose sublingual ketamine and his patients have been able to safely take this at home. Profits from the sales of this book will assist further research into the use of ketamine for the treatment of depression.
Ketamine
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Author : Kenji Hashimoto
language : en
Publisher: Springer Nature
Release Date : 2020-03-05
Ketamine written by Kenji Hashimoto and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-05 with Medical categories.
This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse. The first part of the book focuses on the evidence regarding ketamine abuse, with specific reference to Asian countries, and discusses countermeasures and complication management. It then addresses the mechanisms underlying the antidepressant and side effects of ketamine, which have remained elusive, describing and discussing important new research findings. Further, it explains insights gained from whole brain imaging in rodents and from behavioral pharmacology, and presents evidence regarding the role of gut microbiota, the NMDA receptor GluN2D subunit, and the lateral habenula in the actions of ketamine. These advances form the basis for the safer use of ketamine in patients with treatment-resistant depression and are expected to lead to the development of new antidepressants.
Managing Treatment Resistant Depression
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Author : Joao Quevedo
language : en
Publisher: Academic Press
Release Date : 2022-03-31
Managing Treatment Resistant Depression written by Joao Quevedo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Science categories.
Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD. Defines Treatment-Resistant Depression and Staging Treatment Intensity Includes Treatment-Resistant Depression options for children, adolescents, geriatrics, during pregnancy, and during post-partum and menopause transitions Discusses the use of Ketamine and Esketamine for treatment-resistant depression
Rapid Acting Antidepressants
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-06-29
Rapid Acting Antidepressants written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-29 with Medical categories.
The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Treatment Resistant Mood Disorders
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Author : André Carvalho
language : en
Publisher: Oxford Psychiatry Library
Release Date : 2015
Treatment Resistant Mood Disorders written by André Carvalho and has been published by Oxford Psychiatry Library this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.
Treatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. Providing a concise view of the current definitions, assessment and evidence-based management of such disorders, this work reviews novel therapeutic targets, which may enhance the future therapeutic armamentarium of clinicians.
Treatment Resistant Depression
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-07-05
Treatment Resistant Depression written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-05 with Science categories.
Progress in Brain Research, Volume 278, the latest release in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters on Treatment Resistant Depression overview in Adult, Treatment Resistant Depression in Children and Adolescents, Treatment Resistant Depression in Elderly, Headache and Treatment Resistant Depression, Insomnia and Treatment Resistant Depression, Tinnitus and Treatment Resistant Depression, Genetics of Antidepressant Response and Treatment Resistant Depression, Neuroinflammation via Gut-Microbiota-Brain Axis in Treatment Resistant Depression, Molecular Imaging findings for Treatment Resistant Depression, and more. Additional sections cover Functional MRI markers for Treatment Resistant Depression: Insights and Current Challenges, Medication Strategies for Treatment Resistant Depression, Brain Stimulation for Treatment Resistant Depression, Electroconvulsive Therapy for Treatment Resistant Depression, Next Generation Antidepressants with Novel Mechanisms for Treatment Resistant Depression, Psychological aspects and Psychotherapy for Treatment Resistant Depression, and Psychiatric Rehabilitation for Treatment Resistant Depression. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Progress in Brain Research serials Updated release includes the latest information on Treatment-Resistant Depression
Therapeutic Use Of Ketamine In Psychiatric Disorders
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Author : Jennifer Lee Jones
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-04
Therapeutic Use Of Ketamine In Psychiatric Disorders written by Jennifer Lee Jones and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-04 with Medical categories.
Bridging The Gap An Interdisciplinary Perspective On Ketamine In Psychiatric Disorders
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Author : Lucie Bartova
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-07
Bridging The Gap An Interdisciplinary Perspective On Ketamine In Psychiatric Disorders written by Lucie Bartova and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-07 with Medical categories.