Kidney Development And Disease
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Kidney Development And Disease
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Author : Rachel K. Miller
language : en
Publisher: Springer
Release Date : 2017-04-13
Kidney Development And Disease written by Rachel K. Miller and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-13 with Science categories.
Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.
Kidney Development Disease Repair And Regeneration
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Author : Melissa Helen Little
language : en
Publisher: Academic Press
Release Date : 2015-08-06
Kidney Development Disease Repair And Regeneration written by Melissa Helen Little and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-06 with Medical categories.
Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally Explains the underlying developmental mechanisms which influence the kidney’s inherent repair capacity Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine
Kidney Development In Renal Pathology
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Author : Gavino Faa
language : en
Publisher: Springer
Release Date : 2014-08-09
Kidney Development In Renal Pathology written by Gavino Faa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-09 with Medical categories.
This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life and the correlation with renal carcinogenesis. Written by well recognized experts in their fields, Kidney Development in Renal Pathology is a valuable tool for pathologists, neonatologists, nephrologists, gynecologists and researchers with an interest in kidney diseases.
The Kidney
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Author : Peter D. Vize
language : en
Publisher: Elsevier
Release Date : 2003-03-14
The Kidney written by Peter D. Vize and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-14 with Science categories.
Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage of the kidney. Hundreds of color figures depicting key events in all aspects of kidney development Full coverage of the genetic and cellular basis of kidney development Analysis of the genetic basis of the major congenital kidney diseases
Factors Influencing Mammalian Kidney Development Implications For Health In Adult Life
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Author : Karen Moritz
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-05-11
Factors Influencing Mammalian Kidney Development Implications For Health In Adult Life written by Karen Moritz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-11 with Medical categories.
In this monograph the authors have emphasized a number of important concepts in mammalian kidney development. Emphasis has been put on methodology so that the reader can understand how certain results or conclusions were reached and what the optimal methods for reliable results to be obtained are. In addition, as well as descriptions of the morphology there is information on the genetic basis of the structural development. In addition much attention has been paid to how nephron number may be altered by changes in the environment of the developing kidney and to the consequences for the remaining nephron gene expression and kidney function when total nephron number is altered. The consequences for the health of the adult, upon the formation of an adult kidney with altered nephron number and (potentially) gene expression, can be quite serious. The epigenetic mechanisms by which such changes can occur are introduced as a very fertile field for future investigation.
Kidney Development
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Author : Odyss Michos
language : en
Publisher: Humana Press
Release Date : 2016-05-01
Kidney Development written by Odyss Michos and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-01 with Medical categories.
Reflecting recent revolutionary advances in our understanding of renal development, this volume details step-by-step protocols researchers can deploy in their own work, including 3-D morphogenetic mapping and assessing kidney malformation and morbidity.
Pediatric Kidney Disease
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Author : Denis F. Geary
language : en
Publisher: Springer
Release Date : 2017-02-16
Pediatric Kidney Disease written by Denis F. Geary and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-16 with Medical categories.
The new edition of this valuable clinical resource offers a state of the art, comprehensive review on every clinical condition encountered in pediatric nephrology. International experts present the latest knowledge on epidemiology, diagnosis, management, and prognosis in one concise, clinically focused text, in which care has been taken to couple just the right amount of "need-to-know" basic science with practical clinical guidance that will enable the reader to make efficient, informed decisions. The topics covered include: disorders of renal development, glomerular disorders, the kidney and systemic disease, renal tubular disorders, tubulointerstitial disease, urinary tract disorders, acute kidney injury, hypertension, chronic and end-stage renal disease, and renal replacement therapy. The full-color, highly visual, meticulously crafted format will ensure that the practitioner is able to source and apply information with remarkable ease.
Normal And Abnormal Development Of The Kidney
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Author : Edith Louise Potter
language : en
Publisher:
Release Date : 1972
Normal And Abnormal Development Of The Kidney written by Edith Louise Potter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with Medical categories.
Renal Development And Disease
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Author : Michael S. Goligorsky
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2002
Renal Development And Disease written by Michael S. Goligorsky and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Gene expression categories.
Functional genomics is best defined as a tool-kit consisting of a variety of molecular, cellular, and whole-animal approaches, all directed towards elucidation of the role played by genes and their encoded products in maintaining physiological performance or triggering pathologic events. These elements are not controlled by a single gene, but by an ensemble of genes and their products which support the integrated functions of an organ. Understanding the 'wholeness' of these ensembles represents thus a major challenge for functional genomics: It is the spatial and temporal mapping of these processes that constitutes the ultimate goal of biomedical research. This publication is intended to facilitate the recognition of the challenge ahead to provide the tools to address the special requirements of kidney research. Several reviews included describe technical approaches to gene screening, other reviews offer examples of the complexities of gene function in various disease states or their models and an introduction to the use of proteomics to study renal disease. The thoughts and experimental examples gathered in this publication will be a first step in the enormous task ahead towards a better understanding of renal function in health and disease.
Genetic Diseases Of The Kidney
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Author : Richard P. Lifton
language : en
Publisher: Academic Press
Release Date : 2009-02-25
Genetic Diseases Of The Kidney written by Richard P. Lifton and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-25 with Science categories.
Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2,000 disease genes have been identified in the last 20 years, providing important new insight into the pathophysiology of diseases in every field of medicine. Genetic Diseases of the Kidney offers expert insight into the role of genetic abnormalities in the pathogenesis of abnormal kidney function and kidney disease. Genetic abnormalities are carefully presented within the appropriate physiologic context so that readers will understand not only which genes are linked to which diseases but also which pathways lead from a genetic “disturbance” to the systemic appearance of disease. * Lays the essential foundation of mammalian genetics principles for medical professionals with little or no background in genetics * Analyzes specific renal diseases – both monogenic disorders confined to the kidney and systemic diseases with renal involvement – and explains their genetic causes *World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension)