Killer Cell Dynamics
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Killer Cell Dynamics
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Author : Dominik Wodarz
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-04-05
Killer Cell Dynamics written by Dominik Wodarz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-05 with Mathematics categories.
Systems biology and computational biology have recently become prominent areas of research in the biomedical community, especially in the area of cell biology. Given that much information on genes and their protein products has become available, the big question is how the individual components interact and work together, and how this determines the functioning of cells, organs, and organisms. Long before the popularity of systems biology in biomedicine, however, such approaches have been used successfully in a di?erent area of biology: population ecology. Research in the area of population dynamics - vestigated complex interactions between di?erent populations of organisms, such as the dynamics of competition and predation, food webs, community structure, as well as the epidemiology of infectious diseases. In this ?eld, t- oretical biology and mathematical modeling have become an integral part of research. Mathematical models allowed people to obtain interesting and counter-intuitive insights into how complex interactions among di?erent p- ulations can play out. Such mathematical studies not only gave rise to - teresting theoretical ideas, but also provided the basis for the design of new experimental work and de?ned major questions and directions of research. Around 1990, such population dynamic concepts, and the use of mathema- cal/computational approaches, started to be applied to the in vivo dynamics between viruses and the immune system. These interactions have many s- ilarities to ecological, epidemiological, and evolutionary principles. Consider theepidemiologicalspreadofapathogen(suchasthecommoncold)througha population of hosts.
Cellular Dynamics Within The Tumor Microenvironment
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Author : Daniela F. Quail
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-10
Cellular Dynamics Within The Tumor Microenvironment written by Daniela F. Quail and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-10 with Medical categories.
The Second Life Of Natural Killer Nk Cells
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Author : Chiara Romagnani
language : en
Publisher: Frontiers Media SA
Release Date : 2018-07-16
The Second Life Of Natural Killer Nk Cells written by Chiara Romagnani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-16 with categories.
Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of “Innate lymphoid cells” (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to microbial and cell stress stimuli, thus playing a central role in the defense against pathogen infection, in tumor surveillance and in regulating immune homeostasis. Despite these established concepts, our understanding of the complexity of NK cells, also in view of their developmental and functional relationship with other ILC subsets, is only recently emerging. This Research Topic highlights the recent advances in NK cell (and ILC) research in human and mouse from basic research to clinical applications.
Natural Killer Cells
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Author : Srinivas S. Somanchi
language : en
Publisher: Humana Press
Release Date : 2016-05-13
Natural Killer Cells written by Srinivas S. Somanchi and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-13 with Medical categories.
This volume contains collection of Natural Killer Cell methodologies relevant for both basic and translational research. These methodologies present new developments in the natural killer (NK) cell field, such as understanding the influence of NK cells metabolism on its function, identifying complexity of NK cell subsets through mass cytometry, and determining the emergence of memory NK cells in murine model of MCMV infection. Methods that study NK cell migration and cytotoxicity through endpoint analysis or live single cell imaging are also discussed. Chapters also describe methods pertaining to translational application of NK cells, such as ex vivo expansion of NK cells on K562 cell lines genetically modified to express either membrane bound IL-15 or membrane bound IL-21, large scale NK cell culture, current techniques for engineering NK cells to express chimeric antigen receptors or chemokine receptors using retroviral vectors, electroporation of mRNA, and the natural phenomenon of trogocytosis. Written in the highly successful Methods in Molecular Biology series format, these chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, Natural Killer Cells: Methods and Protocols is a valuable resource for researchers who not only want to understand mechanisms that govern NK cell behavior and diversity, but also for those who want to understand how to systematically evaluate NK cells for adoptive immunotherapy applications.
Natural Killer Cells
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Author : Michael T. Lotze
language : en
Publisher: Academic Press
Release Date : 2009-11-12
Natural Killer Cells written by Michael T. Lotze and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-12 with Medical categories.
Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine. - Provides a broad, detailed coverage of the biology and interactions of NK cells for students, fellows, scientists, and practitioners - Includes figures, histologic sections, and illustrations of the ontogeny of NK cells
Geometry And Topology In Hamiltonian Dynamics And Statistical Mechanics
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Author : Marco Pettini
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-14
Geometry And Topology In Hamiltonian Dynamics And Statistical Mechanics written by Marco Pettini and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-14 with Mathematics categories.
Itisaspecialpleasureformetowritethisforewordforaremarkablebookbya remarkableauthor.MarcoPettiniisadeepthinker,whohasspentmanyyears probing the foundations of Hamiltonian chaos and statistical mechanics, in particular phase transitions, from the point of view of geometry and topology. Itisinparticularthequalityofmindoftheauthorandhisdeepphysical,as well as mathematical insights which make this book so special and inspiring. It is a “must” for those who want to venture into a new approach to old problems or want to use new tools for new problems. Although topology has penetrated a number of ?elds of physics, a broad participationoftopologyintheclari?cationandprogressoffundamentalpr- lems in the above-mentioned ?elds has been lacking. The new perspectives topology gives to the above-mentioned problems are bound to help in their clari?cation and to spread to other ?elds of science. The sparsity of geometric thinking and of its use to solve fundamental problems, when compared with purely analytical methods in physics, could be relieved and made highly productive using the material discussed in this book. It is unavoidable that the physicist reader may have then to learn some new mathematics and be challenged to a new way of thinking, but with the author as a guide, he is assured of the best help in achieving this that is presently available.
Molecular And Cellular Pathways In Nk Cell Development
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Author : Ewa Sitnicka
language : en
Publisher: Frontiers Media SA
Release Date : 2020-09-02
Molecular And Cellular Pathways In Nk Cell Development written by Ewa Sitnicka and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-02 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
An Introduction To Mathematical Epidemiology
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Author : Maia Martcheva
language : en
Publisher: Springer
Release Date : 2015-10-20
An Introduction To Mathematical Epidemiology written by Maia Martcheva and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-20 with Mathematics categories.
The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of infectious diseases. It includes model building, fitting to data, local and global analysis techniques. Various types of deterministic dynamical models are considered: ordinary differential equation models, delay-differential equation models, difference equation models, age-structured PDE models and diffusion models. It includes various techniques for the computation of the basic reproduction number as well as approaches to the epidemiological interpretation of the reproduction number. MATLAB code is included to facilitate the data fitting and the simulation with age-structured models.
Adhesion Molecules And Autoimmune Diseases
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Author : Hao Sun
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-19
Adhesion Molecules And Autoimmune Diseases written by Hao Sun and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-19 with Medical categories.
Yen Jaffe S Reproductive Endocrinology E Book
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Author : Jerome F. Strauss
language : en
Publisher: Elsevier Health Sciences
Release Date : 2013-08-28
Yen Jaffe S Reproductive Endocrinology E Book written by Jerome F. Strauss and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-28 with Medical categories.
Yen & Jaffe’s Reproductive Endocrinology helps you successfully diagnose and manage the spectrum of female and male reproductive system diseases, from impaired fertility, infertility, and recurrent pregnancy loss through problems of sexual development, puberty, menstrual disturbances, fibroids, endometriosis, and reproductive aging. This trusted endocrinology reference book is ideal for studying or as a quick reference when making daily diagnostic and therapeutic decisions, ensuring it's just the resource you need to offer your patients the best possible care. Apply the latest reproductive endocrinology advances in basic and clinical science, including molecular, cellular, and genetic concepts, and grasp their relevance to pathophysiology, diagnosis, and therapy. Maximize fertility in women and men undergoing chemotherapy and other cancer treatments, and counsel patients on environmental factors affecting reproduction. Stay on top of recent developments including the impact of obesity on fertility; ovarian tissue banking; cryopreservation; pre-implantation genetic diagnosis; ovulation induction; and risks and treatments for steroid hormone-responsive cancers. View basic anatomic structures, endocrine processes, and cell function and dysfunction with absolute clarity through full-color illustrations and new images throughout. Confidently perform procedures through expanded coverage of reproductive and infertility surgery. Apply the latest reproductive endocrinology advances in basic and clinical science, including molecular, cellular, and genetic concepts, and grasp their relevance to pathophysiology, diagnosis, and therapy. Maximize fertility in women and men undergoing chemotherapy and other cancer treatments, and counsel patients on environmental factors affecting reproduction. Stay on top of recent developments including the impact of obesity on fertility; ovarian tissue banking; cryopreservation; pre-implantation genetic diagnosis; ovulation induction; and risks and treatments for steroid hormone-responsive cancers. View basic anatomic structures, endocrine processes, and cell function and dysfunction with absolute clarity through full-color illustrations and new images throughout.