Kinetic Analysis Of Macromolecules
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Kinetic Analysis Of Macromolecules
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Author : Kenneth Johnson
language : en
Publisher: Oxford University Press on Demand
Release Date : 2003
Kinetic Analysis Of Macromolecules written by Kenneth Johnson and has been published by Oxford University Press on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Science categories.
This new book in the Practical Approach Series contains reviews of state-of-the art kinetic methods applied to the functions and dynamics of proteins and nucleic acids. The book has been written by a team of experts, many of whom developed the methods discussed.
Cell Signaling Reactions
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Author : Yasushi Sako
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-04
Cell Signaling Reactions written by Yasushi Sako and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-04 with Medical categories.
This book encompasses the exciting developments and challenges in the fast-moving and rapidly expanding research field of single-molecule kinetic analysis of cell signaling that promises to be one of the most significant and exciting areas of biological research for the foreseeable future. Cell signaling is carried out by complicated reaction networks of macromolecules, and single-molecule analyses has already demonstrated its power to unravel complex reaction dynamics in purified systems. To date, most of the published research in the field of single-molecule processes in cells, focus on the dynamic properties (translational movements of the centre of mass) of biological molecules. However, we hope that this book presents as many kinetic analyses of cell signaling as possible. Although single-molecule kinetic analysis of cellular systems is a relatively young field when compared with the analysis of single-molecule movements in cells, this type of analysis is highly important because it directly relates to the molecular functions that control cellular behavior and in the future, single-molecule kinetic analysis will be largely directed towards cellular systems. Thus, we hope that this book will be of interest to all those working in the fields of molecular and cell biology, as well as biophysics and biochemistry.
Biomolecular Kinetics
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Author : Clive R. Bagshaw
language : en
Publisher: CRC Press
Release Date : 2017-10-04
Biomolecular Kinetics written by Clive R. Bagshaw and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-04 with Medical categories.
"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.
Cell Signaling Reactions
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Author : Yasushi Sako
language : en
Publisher: Springer
Release Date : 2011-03-25
Cell Signaling Reactions written by Yasushi Sako and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-25 with Medical categories.
This book encompasses the exciting developments and challenges in the fast-moving and rapidly expanding research field of single-molecule kinetic analysis of cell signaling that promises to be one of the most significant and exciting areas of biological research for the foreseeable future. Cell signaling is carried out by complicated reaction networks of macromolecules, and single-molecule analyses has already demonstrated its power to unravel complex reaction dynamics in purified systems. To date, most of the published research in the field of single-molecule processes in cells, focus on the dynamic properties (translational movements of the centre of mass) of biological molecules. However, we hope that this book presents as many kinetic analyses of cell signaling as possible. Although single-molecule kinetic analysis of cellular systems is a relatively young field when compared with the analysis of single-molecule movements in cells, this type of analysis is highly important because it directly relates to the molecular functions that control cellular behavior and in the future, single-molecule kinetic analysis will be largely directed towards cellular systems. Thus, we hope that this book will be of interest to all those working in the fields of molecular and cell biology, as well as biophysics and biochemistry.
Energetics Of Biological Macromolecules Part D
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Author : Jo M. Holt
language : en
Publisher: Elsevier
Release Date : 2004-04-02
Energetics Of Biological Macromolecules Part D written by Jo M. Holt and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-02 with Science categories.
This volume focuses on the cooperative binding aspects of energetics in biological macromolecules. Methodologies such as NMR, small-angle scattering techniques for analysis, calorimetric analysis, fluorescence quenching, and time resolved FRET measurements are discussed. *Methods for Evaluating Cooperativity in a Dimeric Hemoglobin*Multiple-Binding of Ligands to a Linear Biopolymer*Fluorescence Quenching Methods to Study Protein-Nucleic Acid Interactions*Linked Equilibria in Biotin Repressor Function: Thermodynamic, Structural and Kinetic Analysis
Binding And Kinetics For Molecular Biologists
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Author : James Andrew Goodrich
language : en
Publisher: CSHL Press
Release Date : 2007
Binding And Kinetics For Molecular Biologists written by James Andrew Goodrich and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Carrier proteins categories.
This handbook offers a practical guide to the principles of quantitative analysis in biological experiments. The material is primarily aimed at working molecular biologists, but the scope and clarity of presentation make it equally suitable as an introduction for students. Topics covered range from the basics — such as measuring the concentrations of macromolecules — through considerations of binding constants and the kinetics of molecular interactions. The book ends with a thorough consideration of data analysis.
Conformation Of Macromolecules
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Author : Y. G. Medvedevskikh
language : en
Publisher: Nova Publishers
Release Date : 2007
Conformation Of Macromolecules written by Y. G. Medvedevskikh and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Science categories.
Conformation is statistical property of the macromolecules consisting of a number of N structural units, links, position of which in a space one relatively to other is not inflexibly fixed by chemical bonds and assumes the possible random configurations. The number of possible configurations at N ” 1 is so great that permits to use the statistical methods at their analysis. That is why the conformation is a result of statistical averaging on all possible configurations of the macromolecule. It was for a long time notified and confirmed by computer modelling that the conformation of polymeric chain should be described by self-avoiding random walks statistics (SARW) but not Gaussian random walks statistics, assuming the phantom behaviour of polymeric chains. Nevertheless, Gaussian statistics is dominating at the analysis of thermodynamic, dynamic and kinetic stainings of the macromolecules conformation. This book will be useful for scientists who are engaged in the physical chemistry of polymers and their solutions.
Kinetics For The Life Sciences
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Author : H. Gutfreund
language : en
Publisher: Cambridge University Press
Release Date : 1995-09-14
Kinetics For The Life Sciences written by H. Gutfreund and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-09-14 with Medical categories.
The aim of the book is to introduce the reader to the kinetic analysis of a wide range of biological processes at the molecular level. It is intended to show that the same approach can be used to resolve the number of steps in enzyme reactions, muscle contraction, visual perception and ligand binding receptors that trigger other physiological processes. Attention is also given to methods for characterizing these steps in chemical terms. Although the treatment is mainly theoretical, a wide range of examples and experimental techniques are also introduced and an historical approach is used to demonstrate the development of the theory and experimental techniques of kinetic analysis in biology.
Energetics Of Biological Macromolecules
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Author : Michael L. Johnson
language : en
Publisher: Elsevier
Release Date : 1998
Energetics Of Biological Macromolecules written by Michael L. Johnson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Allosteric regulation categories.
Essential publication for researchers in all fields of life sciences. Key Features * Major topics covered include: * Deciphering rules of helix stability in peptides * Protein Folding in Membranes * Molecular Crowding * Study of the Bohr Effect in Hemoglobin Intermediates * Photoacoustic Calorimetry of Proteins * Theoretical Aspects of Isothermal Titration Calorimetry * Energetic Methods to Study Bifunctional Biotin Repressor.
Principles Of Enzyme Kinetics
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Author : Athel Cornish-Bowden
language : en
Publisher: Elsevier
Release Date : 2014-05-20
Principles Of Enzyme Kinetics written by Athel Cornish-Bowden and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-20 with Science categories.
Principles of Enzyme Kinetics discusses the principles of enzyme kinetics at an intermediate level. It is primarily written for first-year research students in enzyme kinetics. The book is composed of 10 chapters. Chapter 1 provides the basic principles of enzyme kinetics with a brief discussion of dimensional analysis. Subsequent chapters cover topics on the essential characteristics of steady-state kinetics, temperature dependence, methods for deriving steady-state rate equations, and control of enzyme activity. Integrated rate equations, and introductions to the study of fast reactions and the statistical aspects of enzyme kinetics are provided as well. Chemists and biochemists will find the book invaluable.