Kinetics Of Enzyme Catalysis
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Enzyme Kinetics Catalysis And Control
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Author : Daniel L. Purich
language : en
Publisher: Elsevier
Release Date : 2010-06-16
Enzyme Kinetics Catalysis And Control written by Daniel L. Purich and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-16 with Science categories.
Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. Historical analysis of kinetic principles including advanced enzyme science Provides both theoretical and practical measurements tools Coverage of single molecular kinetics Examination of force generation mechanisms Discussion of organic and inorganic enzyme reactions
Kinetics Of Enzyme Catalysis
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Author : Bruce Palfey
language : en
Publisher: American Chemical Society
Release Date : 2022-04-20
Kinetics Of Enzyme Catalysis written by Bruce Palfey and has been published by American Chemical Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-20 with Science categories.
Kinetics of Enzyme Catalysis provides an introduction to the fundamentals of understanding an enzyme's catalytic mechanism and how activity is regulated, which is key to understanding biology and many diseases. Kinetics is at the core of enzymology, as it must be for the study of catalysts. Kinetics of Enzyme Catalysis examines simple kinetics and then applies those ideas to enzyme mechanisms, leading to rate equations for several key mechanisms and, as important, illustrating some key principles. A reader should therefore come away empowered with some mathematical tools allowing the analysis of catalytic cycles not discussed here and also with the understanding to predict some behaviors of enzyme kinetics without any math. Methods are discussed in some detail, and with them some considerations for avoiding pitfalls and collecting reliable data. In addition, introductions are presented to the important areas of studying inhibitors, of the origins of the catalytic power of enzymes, and the use of rapid-reaction technology.
Enzymes Catalysis Kinetics And Mechanisms
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Author : N.S. Punekar
language : en
Publisher: Springer
Release Date : 2018-11-11
Enzymes Catalysis Kinetics And Mechanisms written by N.S. Punekar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-11 with Science categories.
This enzymology textbook for graduate and advanced undergraduate students covers the syllabi of most universities where this subject is regularly taught. It focuses on the synchrony between the two broad mechanistic facets of enzymology: the chemical and the kinetic, and also highlights the synergy between enzyme structure and mechanism. Designed for self-study, it explains how to plan enzyme experiments and subsequently analyze the data collected. The book is divided into five major sections: 1] Introduction to enzymes, 2] Practical aspects, 3] Kinetic Mechanisms, 4] Chemical Mechanisms, and 5] Enzymology Frontiers. Individual concepts are treated as stand-alone chapters; readers can explore any single concept with minimal cross-referencing to the rest of the book. Further, complex approaches requiring specialized techniques and involved experimentation (beyond the reach of an average laboratory) are covered in theory with suitable references to guide readers. The book provides students, researchers and academics in the broad area of biology with a sound theoretical and practical knowledge of enzymes. It also caters to those who do not have a practicing enzymologist to teach them the subject.
Comprehensive Enzyme Kinetics
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Author : Vladimir Leskovac
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-03-31
Comprehensive Enzyme Kinetics written by Vladimir Leskovac and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-31 with Medical categories.
Annotation This text for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady-state enzyme kinetics from the basic principles inherent in the Michaelis-Menten equation to expressions that describe the multi-substrate enzyme reactions, providing a framework for the study of enzymes with the aid of kinetic studies of enzyme-catalyzed reactions. Discussion encompasses chemical kinetics, kinetics of monosubstrate reactions, and cooperative and allosteric effects. The editor is affiliated with the University of Novi Sad. Annotation (c)2003 Book News, Inc., Portland, OR (booknews.com).
Kinetics Of Chemical And Enzyme Catalyzed Reactions
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Author : Dennis Piszkiewicz
language : en
Publisher:
Release Date : 1977
Kinetics Of Chemical And Enzyme Catalyzed Reactions written by Dennis Piszkiewicz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with categories.
A Study Of Enzymes
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Author : Stephen A. Kuby
language : en
Publisher: CRC Press
Release Date : 2019-07-23
A Study Of Enzymes written by Stephen A. Kuby and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with Medical categories.
First published in 1990, this comprehensive monograph consists of two parts: Volume I, entitled Enzyme Catalysis, Kinetics, and Substrate Binding; and Volume II, entitled Mechanism of Enzyme Action. Volume I focuses on several aspects of enzyme catalytic behavior, their steady-state and transient-state kinetics, and the thermodynamic properties of substrate binding. Packed with figures, tables, schemes, and photographs, this volume contains over 1,000 references, including references regarding enzymology's fascinating history. This comprehensive book is of particular interest to enzymology students, teachers, and researchers. Volume II presents selected "cutting edge" examples of techniques and approaches being pursued in biochemistry. This up-to-date resource includes 11 chapters, which illustrate important theoretical and practical aspects of enzyme mechanisms. It also features selected examples in which today's most important techniques, ideas, and theories are used to elaborate on the intricate nature of enzyme action mechanisms. This particular volume provides important information for both the novice and the seasoned investigator.
Enzyme Kinetics And Mechanism
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Author : Vern L Schramm (Ed)
language : en
Publisher:
Release Date : 1999
Enzyme Kinetics And Mechanism written by Vern L Schramm (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Enzyme Catalysis And Regulation
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Author : Gorden Hammes
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Enzyme Catalysis And Regulation written by Gorden Hammes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Enzyme Catalysis and Regulation is an introduction to enzyme catalysis and regulation and covers topics ranging from protein structure and dynamics to steady-state enzyme kinetics, multienzyme complexes, and membrane-bound enzymes. Case studies of selected enzyme mechanisms are also presented. This book consists of 11 chapters and begins with a brief overview of enzyme structure, followed by a discussion on methods of probing enzyme structure such as X-ray crystallography and optical spectroscopy. Kinetic methods are then described, with emphasis on the general principles of steady-state and transient kinetics. The chemical principles involved in enzyme catalysis are also discussed, and case studies of a few well-documented enzymes are presented. The regulation of enzyme activity is analyzed from a nongenetic viewpoint, with particular reference to binding isotherms and models for allosterism. Two particular enzymes, aspartate transcarbamoylase and phosphofructokinase, are used as examples of well-studied regulatory enzymes. The last two chapters focus on multienzyme complexes and membrane-bound enzymes. This monograph is intended for graduate students, advanced undergraduates, and research workers in molecular biology and biochemistry.
Enzyme Kinetics And Mechanisms Part E Energetics Of Enzyme Catalysis
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Author :
language : en
Publisher: Elsevier
Release Date : 1999-09-06
Enzyme Kinetics And Mechanisms Part E Energetics Of Enzyme Catalysis written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-06 with Science categories.
This volume supplements Volumes 63, 64, 87, and 249 of Methods in Enzymology. These volumes provide a basic source for the quantitative interpretation of enzyme rate data and the analysis of enzyme catalysis. Among the major topics covered are Engergetic Coupling in Enzymatic Reactions, Intermediates and Complexes in Catalysis, Detection and Properties of Low Barrier Hydrogen Bonds, Transition State Determination, and Inhibitors. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
New Trends In Enzyme Catalysis And Biomimetic Chemical Reactions
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Author : Gertz I. Likhtenshtein
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-08
New Trends In Enzyme Catalysis And Biomimetic Chemical Reactions written by Gertz I. Likhtenshtein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-08 with Science categories.
"This book is a view of enzyme catalysis by a physico-chemist with long-term experience in the investigation of structure and action mechanism of biological catalysts. This book is not intended to provide an exhaustive survey of each topic but rather a discussion of their theoretical and experimental background, and recent developments. The literature of enzyme catalysis is so vast and many scientists have made important contribution in the area, that it is impossible in the space allowed for this book to give a representative set of references. The author has tried to use reviews, and general principles of articles. He apologizes to those he has not been able to include. . ... The monograph is intended for scientists working on enzyme catalysis and adjacent areas such as chemical modeling of biological processes, homogeneous catalysis, biomedical research and biotechnology. The book can be use as a subsidiary manual for instructors, graduate and undergraduate students of university biochemistry and chemistry departments."--Pages ix-x.