Laboratory Methods For The Detection Of Mutations And Polymorphisms In Dna
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Laboratory Methods For The Detection Of Mutations And Polymorphisms In Dna
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Author : Graham R. Taylor
language : en
Publisher: CRC Press
Release Date : 1997-01-24
Laboratory Methods For The Detection Of Mutations And Polymorphisms In Dna written by Graham R. Taylor and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-01-24 with Science categories.
The analysis of DNA sequence polymorphisms and mutations is of central importance in understanding biological systems. This book is devoted to the experimental analysis of DNA and presents easy-to-follow protocols. Various techniques from the simple to the highly complex are detailed in this volume, providing a wide spectrum of available methods and practical advice. The methods are described in terms of: History and background Principles and theory Equipment and reagents Protocols Troubleshooting Applications Improvements Results Comparisons with other methods Future prospects and developments This is an essential manual for researchers working in human, animal, or plant molecular genetics and is particularly valuable for hospital and commercial laboratories.
Genetics Manual
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Author : G. P. Rdei
language : en
Publisher: World Scientific
Release Date : 1998
Genetics Manual written by G. P. Rdei and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Science categories.
"Redei has created an outstanding compendium of genetics. Arranged as a dictionary, the book is almost an encyclopedic collection of terms & concepts ... The author has managed to define terms with appropriate mixtures of depth & detail for the researcher, along with clarity useful for the nonexpert." Choice, 1998
Analysis Of Multifactorial Diseases
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Author : D T Bishop
language : en
Publisher: Taylor & Francis
Release Date : 2024-12-06
Analysis Of Multifactorial Diseases written by D T Bishop and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-06 with Medical categories.
Analysis of Multifactorial Diseases examines the evidence of genetic factors that increase susceptibility to a range of complex diseases and describes the approaches taken to identify these genes. It reviews the successes and failures and examines whether there are any general conclusions to be drawn from this current range of approaches.
Molecular Methods In Ecology
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Author : Allan Baker
language : en
Publisher: John Wiley & Sons
Release Date : 2009-04-01
Molecular Methods In Ecology written by Allan Baker and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-01 with Science categories.
The incorporation of molecular methods in ecological research has added an exciting new dimension to conventional studies, and opened windows into previously intractable areas of research, at the interface between ecology and genetics. Using these new methods it has now become routine to use genetic markers to study ecological phenomena, from molecular sexing of individuals and parentage of offspring, through to population structure of species and phylogenetic relationships of taxa. These methods have stimulated an explosion of empirical and analytical developments in molecular ecology, which have in turn, increasingly attracted students and professional biologists eager to employ them in their studies. Molecular Methods in Ecology traces the development of molecular ecology by reviewing basic molecular biological techniques and earlier methods such as protein electrophoresis, DNA-DNA hybridisation, restriction analysis of DNA, and DNA fingerprinting. Later chapters review methods using newer classes of markers such as microsatellites, introns, MHC, SSRs and AFLP markers in plants and molecular sexing in animals. The strengths and limitations of methods are discussed and guidance is provided in selecting the most appropriate methods for particular problems in ecology. This book will provide both postgraduates and researchers with a guide to choosing and employing appropriate methodologies for successful research in the field of molecular ecology. Provides up-to-date summaries of the latest molecular approaches in this rapidly expanding field. Gives guidance on the appropriate choice of methods for particular problems in ecology, and their strengths and limitations. Provides brief laboratory protocols for each molecular method and summaries of software available for analysis of data in molecular ecology. Outlines examples of the latest research results from studies of both plants and animals, integrated within the framework of molecular ecology.
Molecular Diagnosis Of Genetic Diseases
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Author : Rob Elles
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01
Molecular Diagnosis Of Genetic Diseases written by Rob Elles and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.
This completely revised and updated second edition to integrates the many new technologies and insights now available for the diagnosis of genetic diseases. The authors use such methodologies as PCR optimization dosage analysis, mutation scanning, and quantitative fluorescent PCR for aneuploidy analysis, Neurofibromatosis type 1, and Duchenne muscular dystrophy. These largely generic methodologies may be adapted to most genetic conditions for which a molecular diagnosis is relevant, no matter how frequent or rare their incidence. Molecular Diagnosis of Genetic Diseases, Second Edition offers diagnostic molecular geneticists a unique opportunity to sharpen their scientific skills in the design of assays, their execution, and their interpretation.
Advances In Clinical Chemistry
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-04-19
Advances In Clinical Chemistry written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-19 with Science categories.
Advances in Clinical Chemistry, Volume 80, the latest installment in this internationally acclaimed series, covers a variety of topics relating to the topic. Users will find new chapters on Triglycerides Revisited to the Serial, PCR-Based Detection Methods for Single Nucleotide Polymorphism or Mutation: Real-Time PCR and its Substantial Contribution Towards Technological Refinement, Advances in Circulating Tumor DNA Analysis, Advances in Molecular Diagnosis of Malaria, and Rapid Assessment of Drugs of Abuse. This series contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists who discuss the latest and most up-to-date technologies related to the field of clinical chemistry. Users of this series will find a resource that is considered to be the benchmark for novel analytical approaches in the clinical laboratory. - Provides the most up-to-date technologies in Clinical Chemistry and Clinical Laboratory Science - Authored by world renowned clinical laboratory scientists, physicians and research scientist - Presents the international benchmark for novel analytical approaches in the clinical laboratory
Salmonid Fishes
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Author : Yuri P. Altukhov
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Salmonid Fishes written by Yuri P. Altukhov and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Technology & Engineering categories.
This important title encompasses features of genetic processes in complexly organised population systems of salmonids, one of the most commercially valuable families of fish worldwide. Translated from the original work in Russian, the authors have taken the opportunity to update and revise the work, much of it appearing in the English language for the first time. Covering such important concepts as optimal gene diversity and the unfavourable influence of fishery and hatchery reproduction on the genetic structure of salmon populations, the authors have drawn together a huge wealth of information that will form the cornerstone of much new work in the future. The authors of Salmonid Fishes have between them many years of research experience and practical knowledge in the area and the English translation of this important work, which has been edited by Professor John Thorpe and Professor Gary Carvalho, provides vital information for all those involved in salmonid management, exploitation and conservation, including fish biologists, fisheries managers, conservation and population biologists, ecologists and geneticists.
Henry S Clinical Diagnosis And Management By Laboratory Methods E Book
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Author : Richard A. McPherson
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-04-05
Henry S Clinical Diagnosis And Management By Laboratory Methods E Book written by Richard A. McPherson and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-05 with Medical categories.
Recognized as the definitive reference in laboratory medicine since 1908, Henry's Clinical Diagnosis continues to offer state-of-the-art guidance on the scientific foundation and clinical application of today's complete range of laboratory tests. Employing a multidisciplinary approach, it presents the newest information available in the field, including new developments in technologies and the automation platforms on which measurements are performed. Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection. Features a full-color layout, illustrations and visual aids, and an organization based on organ system. Features the latest knowledge on cutting-edge technologies of molecular diagnostics and proteomics. Includes a wealth of information on the exciting subject of omics; these extraordinarily complex measurements reflect important changes in the body and have the potential to predict the onset of diseases such as diabetes mellitus. Coverage of today's hottest topics includes advances in transfusion medicine and organ transplantation; molecular diagnostics in microbiology and infectious diseases; point-of-care testing; pharmacogenomics; and the microbiome. Toxicology and Therapeutic Drug Monitoring chapter discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users.
Molecular Diagnostics
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Author : William B. Coleman
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-18
Molecular Diagnostics written by William B. Coleman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-18 with Medical categories.
Notable practitioners describe how laboratory medicine is practiced today and illuminate how it will function tomorrow as the revolutionary advances afforded by molecular diagnostics become increasingly central to effective analysis. Proceeding from a discussion of elementary nucleic acid technology to a review of the more advanced techniques, the distinguished contributors lay the groundwork for a comprehensive understanding of their applications throughout clinical medicine. The result is a detailed description of those molecular technologies currently used in diagnostic laboratories, as well as those that seem particularly promising. Detailed discussions of specific clinical applications include those for cancer, hematological malignancies, cardiovascular disease, and neuromuscular, endocrine, and infectious diseases.
Molecular Genetic Epidemiology
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Author : Ian N.M. Day
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-10-23
Molecular Genetic Epidemiology written by Ian N.M. Day and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-23 with Science categories.
This volume describes high-throughput approaches to a series of robust, established methodologies in molecular genetic studies of population samples. Such developments have been essential not only to linkage and association studies of single-gene and complex traits in humans, animals and plants, but also to the characterisation of clone banks, for example in mapping of genomes. Chapters have been written by developers or highly experienced end-users concerned with a diverse array of biological applications. The book should appeal to any researcher for whom costs and throughput in their genetics laboratory have become an issue.