Labs On Chip
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Lab On A Chip Fabrication And Application
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Author : Margarita Stoytcheva
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-06-29
Lab On A Chip Fabrication And Application written by Margarita Stoytcheva and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-29 with Science categories.
The necessity of on-site, fast, sensitive, and cheap complex laboratory analysis, associated with the advances in the microfabrication technologies and the microfluidics, made it possible for the creation of the innovative device lab-on-a-chip (LOC), by which we would be able to scale a single or multiple laboratory processes down to a chip format. The present book is dedicated to the LOC devices from two points of view: LOC fabrication and LOC application.
Lab On A Chip Technology Fabrication And Microfluidics
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Author : K. E. Herold
language : en
Publisher: Horizon Scientific Press
Release Date : 2009
Lab On A Chip Technology Fabrication And Microfluidics written by K. E. Herold and has been published by Horizon Scientific Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Science categories.
Theoretical and technical information on current LOC technologies, and the design and development of LOC systems, methods and applications.
Labs On Chip
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Author : Eugenio Iannone
language : en
Publisher: CRC Press
Release Date : 2018-09-03
Labs On Chip written by Eugenio Iannone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Medical categories.
Labs on Chip: Principles, Design and Technology provides a complete reference for the complex field of labs on chip in biotechnology. Merging three main areas— fluid dynamics, monolithic micro- and nanotechnology, and out-of-equilibrium biochemistry—this text integrates coverage of technology issues with strong theoretical explanations of design techniques. Analyzing each subject from basic principles to relevant applications, this book: Describes the biochemical elements required to work on labs on chip Discusses fabrication, microfluidic, and electronic and optical detection techniques Addresses planar technologies, polymer microfabrication, and process scalability to huge volumes Presents a global view of current lab-on-chip research and development Devotes an entire chapter to labs on chip for genetics Summarizing in one source the different technical competencies required, Labs on Chip: Principles, Design and Technology offers valuable guidance for the lab-on-chip design decision-making process, while exploring essential elements of labs on chip useful both to the professional who wants to approach a new field and to the specialist who wants to gain a broader perspective.
Error Tolerant Biochemical Sample Preparation With Microfluidic Lab On Chip
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Author : Sudip Poddar
language : en
Publisher: CRC Press
Release Date : 2022-07-27
Error Tolerant Biochemical Sample Preparation With Microfluidic Lab On Chip written by Sudip Poddar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-27 with Technology & Engineering categories.
Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.
Microfluidics And Multi Organs On Chip
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Author : P. V. Mohanan
language : en
Publisher: Springer Nature
Release Date : 2022-07-11
Microfluidics And Multi Organs On Chip written by P. V. Mohanan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-11 with Medical categories.
This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.
Lab On A Chip Technology Fabrication And Microfluidics
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Author : K. E. Herold
language : en
Publisher: Caister Academic Press Limited
Release Date : 2009
Lab On A Chip Technology Fabrication And Microfluidics written by K. E. Herold and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Science categories.
Theoretical and technical information on current LOC technologies, and the design and development of LOC systems, methods and applications.
Lab On A Chip
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Author : Yehya H. Ghallab
language : en
Publisher: Artech House
Release Date : 2010
Lab On A Chip written by Yehya H. Ghallab and has been published by Artech House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Biomedical engineering categories.
HereOCOs a groundbreaking book that introduces and discusses the important aspects of lab-on-a-chip, including the practical techniques, circuits, microsystems, and key applications in the biomedical, biology, and life science fields. Moreover, this volume covers ongoing research in lab-on-a-chip integration and electric field imaging. Presented in a clear and logical manner, the book provides you with the fundamental underpinnings of lab-on-a-chip, presents practical results, and brings you up to date with state-of-the-art research in the field. This unique resource is supported with over 160 illustrations that clarify important topics throughout.
Microfluidic Lab On A Chip For Chemical And Biological Analysis And Discovery
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Author : Paul C.H. Li
language : en
Publisher: CRC Press
Release Date : 2005-11-01
Microfluidic Lab On A Chip For Chemical And Biological Analysis And Discovery written by Paul C.H. Li and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-01 with Science categories.
The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated. This microscale advantage translates into greater sensitivity, more accurate results, and better information. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery focuses on all aspects of the microfluidic lab-on-a-chip technologies and offers an overview of the available technology, its limitations, and its breakthroughs over the years. It emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays and enzymatic assays. Originally conceived as a single chapter published in Ewing's Analytical Instrumentation, this book is a gateway to the vast literature and conference proceedings on the topic. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery expands upon its roots to present a comprehensive treatment of microfluidic lab-on-a-chip methods and applications for novices and advanced researchers alike.
Point Of Care Diagnostics On A Chip
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Author : David Issadore
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-01-19
Point Of Care Diagnostics On A Chip written by David Issadore and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-19 with Science categories.
The topic of this book is the development of automated and inexpensive tools that transfer medical tests from a specialized clinical laboratory directly to the point of care, using biochip technology. Immediate access to medically relevant biochemical information for doctors and nurses promises to revolutionize patient care and dramatically lower costs. The miniaturization and automation of medical tests are made possible by biochip technology, that integrates advances in integrated circuits, microelectromechanical systems (MEMS), microfluidics, and electronics. The target audience for this book includes engineering and biomedical researchers who would like to develop or apply biochip technology. They can use this book as a review of the field and as a guide for the development of novel biochip technology for point of care medicine. This book can also be used as a teaching tool for engineering and biomedical students, as well as a reference for physicians and health professionals.
Algorithms For Sample Preparation With Microfluidic Lab On Chip
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Author : Sukanta Bhattacharjee
language : en
Publisher: CRC Press
Release Date : 2022-09-01
Algorithms For Sample Preparation With Microfluidic Lab On Chip written by Sukanta Bhattacharjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-01 with Technology & Engineering categories.
Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip