Large Scale Mammalian Cell Culture Technology


Large Scale Mammalian Cell Culture Technology
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Large Scale Mammalian Cell Culture Technology


Large Scale Mammalian Cell Culture Technology
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Author : Lubiniecki
language : en
Publisher: Routledge
Release Date : 2018-05-02

Large Scale Mammalian Cell Culture Technology written by Lubiniecki and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-02 with Medical categories.


An interdisciplinary approach, integrating biochemistry, biology, genetics, and engineering for the effective production of protein pharmaceuticals. The volume offers a biological perspective of large-scale animal cell culture and examines diverse processing strategies, process management, regulator



Large Scale Mammalian Cell Culture Technology


Large Scale Mammalian Cell Culture Technology
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Author : Lubiniecki
language : en
Publisher: Routledge
Release Date : 2018-05-02

Large Scale Mammalian Cell Culture Technology written by Lubiniecki and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-02 with Medical categories.


An interdisciplinary approach, integrating biochemistry, biology, genetics, and engineering for the effective production of protein pharmaceuticals. The volume offers a biological perspective of large-scale animal cell culture and examines diverse processing strategies, process management, regulator



Large Scale Mammalian Cell Culture


Large Scale Mammalian Cell Culture
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Author : Joseph Feder
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Large Scale Mammalian Cell Culture written by Joseph Feder and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.


Large-Scale Mammalian Cell Culture is composed of papers presented as part of a symposium sponsored by the American Chemical Society Division of Microbial and Biochemical Technology at the 188th American Chemical Society National Meeting, held at Philadelphia, Pa., on Aug. 27, 1984. A rapid development of large-scale mammalian cell culture technology for the production of biologically important molecules becomes apparent. This book looks into this technology, its potential for commercial application, and the regulatory concerns posed by its use for the production of human therapeutics.



Large Scale Mammalian Cell Culture


Large Scale Mammalian Cell Culture
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Author : Joseph Feder
language : en
Publisher:
Release Date : 1985

Large Scale Mammalian Cell Culture written by Joseph Feder and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Science categories.




Large Scale Cell Culture Technology


Large Scale Cell Culture Technology
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Author : Bjorn K. Lydersen
language : en
Publisher:
Release Date : 1987

Large Scale Cell Culture Technology written by Bjorn K. Lydersen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.


The Book This book provides the most detailed and comprehensive survey available of the different methods for production of biotechnology products from large scale mammalian and plant cell culture. Methods ranging from fermentation and encapsulation to hollow fibers and fluidized beds are described by the leaders in the field with a section on regulatory considerations. Each production method is described in detail in terms of principles, equipment and results so that informed comparisons and evaluations can be made. Contents Antibody Production with Airlift Fermentors ò Monoclonal Antibody Production in Stirred Reactors ò Microcarrier Cell Culture ò Cellular Microencapsulation for Large-Scale Production of Monoclonal Antibodies ò Entrapment of Cultured Cells in Agarose Beads ò An Automated Hollow Fiber System for the Large Scale Manufacture of Mammalian Cell Secreted Product ò Continuous Cell Culture with Fluidized Sponge Beads ò Perfusion Cell Culture System Based on Ceramic Matrices ò Large Scale Plant Cell Culture ò Safety Considerations for Cell Culture-Derived Biologicals



Large Scale Cell Culture Technology


Large Scale Cell Culture Technology
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Author : Bjorn K. Lydersen
language : en
Publisher: Wiley-Interscience
Release Date : 1993-11-04

Large Scale Cell Culture Technology written by Bjorn K. Lydersen and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-04 with Technology & Engineering categories.


The Book This book provides the most detailed and comprehensive survey available of the different methods for production of biotechnology products from large scale mammalian and plant cell culture. Methods ranging from fermentation and encapsulation to hollow fibers and fluidized beds are described by the leaders in the field with a section on regulatory considerations. Each production method is described in detail in terms of principles, equipment and results so that informed comparisons and evaluations can be made. Contents Antibody Production with Airlift Fermentors * Monoclonal Antibody Production in Stirred Reactors * Microcarrier Cell Culture * Cellular Microencapsulation for Large-Scale Production of Monoclonal Antibodies * Entrapment of Cultured Cells in Agarose Beads * An Automated Hollow Fiber System for the Large Scale Manufacture of Mammalian Cell Secreted Product * Continuous Cell Culture with Fluidized Sponge Beads * Perfusion Cell Culture System Based on Ceramic Matrices * Large Scale Plant Cell Culture * Safety Considerations for Cell Culture-Derived Biologicals



Mammalian Cell Cultures For Biologics Manufacturing


Mammalian Cell Cultures For Biologics Manufacturing
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Author : Weichang Zhou
language : en
Publisher: Springer
Release Date : 2014-01-15

Mammalian Cell Cultures For Biologics Manufacturing written by Weichang Zhou and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with Science categories.


Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.



Cell Culture And Its Application


Cell Culture And Its Application
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Author : Ronald Acton
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Cell Culture And Its Application written by Ronald Acton and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Cell Culture and Its Application covers the proceedings of the First International Cell Culture Congress Symposium, which focuses on how cell culture technology could impact on cell biology. The symposium aims to establish facilities for the cultivation of mammalian cells, which in turn would hopefully enhance basic cell biology research. The book is organized into four symposium and workshop sessions, encompassing 45 chapters. The opening chapter recognizes the interlocking relationship of cell culture technology and substantive cell biology. Chapters 2-5 describe the biochemical events that mark the cell cycle, with emphasis on occurrence of histone phosphorylation at each cycle. A discussion on cell differentiation, as a phenomena of interacting, inductive, and inhomogeneous cell populations, is included in these chapters. The second symposium session deals with signs of a revolution in progress in cell culture technology. This includes impact of tissue culture in physiological research course and in understanding of integrated physiology. The last two symposium sessions cover the large-scale production of virus from tissue cultures for cell antigens. An approach to the study of aging using diploid human cells in culture as a model system is also presented. It involves isolation and characterization of HLA antigens from cultured cells and their contribution to the study of disease. A brief discussion on mycoplasma contamination, microplasma-cell-virus interaction, and advantages and limitations of direct and indirect culture for primary isolation and detection of mycoplasma contamination is provided. The book then proceeds by discussing cell differentiation of specific cell or organ, such as testis, sensory cell, hepatocyte, embryonic muscle cell, and brain cortex. The concluding chapters cover nutritional requirements for cell growth, defined culture media for specific cell type, issues and problems related to large-scale cell production, and quality control. Cell biologists and researchers will find this book invaluable.



Industrial Scale Suspension Culture Of Living Cells


Industrial Scale Suspension Culture Of Living Cells
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Author : Hans-Peter Meyer
language : en
Publisher: John Wiley & Sons
Release Date : 2014-08-04

Industrial Scale Suspension Culture Of Living Cells written by Hans-Peter Meyer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-04 with Science categories.


The submersed cultivation of organisms in sterile containments or fermenters has become the standard manufacturing procedure, and will remain the gold standard for some time to come. This book thus addresses submersed cell culture and fermentation and its importance for the manufacturing industry. It goes beyond expression systems and integrally investigates all those factors relevant for manufacturing using suspension cultures. In so doing, the contributions cover all industrial cultivation methods in a comprehensive and comparative manner, with most of the authors coming from the industry itself. Depending on the maturity of the technology, the chapters address in turn the expression system, basic process design, key factors affecting process economics, plant and bioreactor design, and regulatory aspects.



Handbook Of Industrial Cell Culture


Handbook Of Industrial Cell Culture
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Author : Victor A. Vinci
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-12-06

Handbook Of Industrial Cell Culture written by Victor A. Vinci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-06 with Science categories.


A diverse team of researchers, technologists, and engineers describe, in simple and practical language, the major current and evolving technologies for improving the biocatalytic capabilities of mammalian, microbial, and plant cells. The authors present state-of-the-art techniques, proven methods, and strategies for industrial screening, cultivation, and scale-up of these cells, and describe their biotech and industrial uses. Special emphasis is given to the solving critical issues encountered during the discovery of new drugs, process development, and the manufacture of new and existing compounds. Other topics include recombinant protein expression, bioinformatics, high throughput screening, analytical tools in biotechnology, DNA shuffling, and genomics discovery.