Leucine Rich Repeat Kinase 2 Lrrk2
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Leucine Rich Repeat Kinase 2 Lrrk2
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Author : Hardy J. Rideout
language : en
Publisher: Springer
Release Date : 2017-03-28
Leucine Rich Repeat Kinase 2 Lrrk2 written by Hardy J. Rideout and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-28 with Medical categories.
This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
A Synopsis Of Parkinson S Disease
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Author : Md, Frcpc, Frcp (hon), Abdul Qayyum Rana
language : en
Publisher: BoD – Books on Demand
Release Date : 2014-03-26
A Synopsis Of Parkinson S Disease written by Md, Frcpc, Frcp (hon), Abdul Qayyum Rana and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-26 with Medical categories.
Parkinsons disease is a disabling neurological condition with both motor and non-motor symptoms for which no cure is available at this stage. This book is unique in covering the most important topics related to Parkinsons disease. Current research and updates about some non-motor symptoms, as well as surgical treatment of Parkinsons disease, in addition to the long term complications of pharmacological treatments have been presented. This book can be used by physicians, researchers and neuroscientists who want to learn new information about these topics related to Parkinsons disease. Authors of the individual chapters are well known in their fields and the book has been edited by a world renowned Parkinsons disease expert.
Genetics Neurology Behavior And Diet In Parkinson S Disease
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Author : Colin R Martin
language : en
Publisher: Academic Press
Release Date : 2020-08-13
Genetics Neurology Behavior And Diet In Parkinson S Disease written by Colin R Martin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-13 with Medical categories.
Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease
Disease Modifying Targets In Neurodegenerative Disorders
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Author : Veerle Baekelandt
language : en
Publisher: Academic Press
Release Date : 2017-03-31
Disease Modifying Targets In Neurodegenerative Disorders written by Veerle Baekelandt and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-31 with Medical categories.
Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment. Provides a comprehensive overview of how key proteins in neurodegenerative disorders can be used as targets to modify disease progress Summarizes how patients are treated today, providing a glance at future disease management Includes intelligible and informative information that is perfect for non-specialists, medical practitioners, and scientists Written and peer reviewed by outstanding scientists in their respective fields
Neurogenetics
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Author :
language : en
Publisher: Elsevier
Release Date : 2018-01-08
Neurogenetics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-08 with Medical categories.
Genetic methodologies are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is evolving rapidly and expected to grow in scope as more disorders are linked to specific genetic markers. Part I covers basic genetic concepts and recurring biological themes, and begins the discussion of movement disorders and neurodevelopmental disorders, leading the way for Part II to cover a combination of neurological, neuromuscular, cerebrovascular, and psychiatric disorders. This volume in the Handbook of Clinical Neurology will provide a comprehensive introduction and reference on neurogenetics for the clinical practitioner and the research neurologist. Presents a comprehensive coverage of neurogenetics Details the latest science and impact on our understanding of neurological psychiatric disorders Provides a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Movement Disorders 4
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Author : Stanley Fahn
language : en
Publisher: Saunders
Release Date : 2010
Movement Disorders 4 written by Stanley Fahn and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Movement Disorders 4, the newest volume in the Blue Books in Neurology series provides you with rapid access to practical, clinical guidance on the diagnosis and pharmacologic treatment on the full range of movement disorders. Emphasizes the vast array of pharmacologic therapeutics, backed by clinical trials of the past 15 years to help you determine the best and most up-to-date drug therapy. Provides the latest on hot topics such as frontotemporal dementia and Tourette's and related disorders, keeping you up to date on today's issues. Presents the surgical management of Parkinson's Disease to help you determine when to recommend surgery and for which patients. Includes extensive comprehensive information on Parkinson's so you can better diagnose and treat PD patients. Offers more clinical details on tremors, differentiating between PD and other movement disorders and the genetics of movement disorders so you can determine which movement disorder is present.
Kinomics
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Author : Heinz-Bernhard Kraatz
language : en
Publisher: John Wiley & Sons
Release Date : 2015-08-11
Kinomics written by Heinz-Bernhard Kraatz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-11 with Science categories.
Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kinome investigation and manipulation. As such, kinase engineering, peptide substrate engineering, co-substrate design and kinase inhibitor design are discussed in detail, and their potential applications in kinome analysis and kinome-based pharmacotherapy are shown. The result is a toolbox for every kinase researcher: By addressing and comparing current approaches to the study of kinase action, both novice and established researchers will benefit from the practical knowledge contained in this invaluable reference.
Neurodegeneration And Alzheimer S Disease
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Author : Ralph N. Martins
language : en
Publisher: John Wiley & Sons
Release Date : 2019-07-10
Neurodegeneration And Alzheimer S Disease written by Ralph N. Martins and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-10 with Technology & Engineering categories.
Understanding the impact of diet, exercise, genetics, and hormones on the risk and development of Alzheimer’s and other neurogenerative diseases Diet is widely known to impact on neurological function. Nevertheless, academic texts discussing this relationship are relatively few in number. This book therefore fills an important gap in the current literature. Opening with an overview of neurodegenerative diseases, particularly Alzheimer’s disease, the text then focuses on explaining the means by which glycemic control and lipid metabolism – and associated nutritional and lifestyle variables – may factor into such disorders’ prevention and treatment. An international group of experts in the fields of food science and neurodegeneration have contributed chapters that examine Alzheimer’s disease within a broad range of contexts. Offering dietary, genetic, and hormonal perspectives, the authors explore topics ranging from sugar consumption to digestive fermentation, and Alzheimer’s disease animal models to the cognition-enhancing effects of physical exercise. Also included are overviews of the latest research into current and developing methods of treatment and diagnosis, as well as differential diagnostics. This groundbreaking book: Explores how glucose metabolism, insulin resistance, lipid metabolism, and high intake of refined carbohydrates are linked to Alzheimer's disease Discusses how genetic makeup can impact risk of Alzheimer’s and Parkinson’s disease Examines cognitive changes in neurodegeneration, lists current tests for determining cognitive impairment, and provides information concerning differential diagnosis Discusses potential advantages of increasing antioxidant and micronutrient intake Reviews hormonal influences on neurodegeneration Examines the links between protein intake and Alzheimer’s disease. Neurodegeneration and Alzheimer's Disease is an essential resource for researchers, medical practitioners, dietitians, and students with an interest in neurological diseases and their diagnosis and risk factors, as well as diet-related conditions such as diabetes and obesity. Lifestyle and diet influence neurodegeneration risk, and a better understanding of this evidence amongst health professionals will hopefully lead to greater public awareness of how to reduce the likelihood of these widespread conditions.
Autophagy And Cancer
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Author : Hong-Gang Wang
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-30
Autophagy And Cancer written by Hong-Gang Wang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-30 with Medical categories.
With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it.
Encyclopedia Of Signaling Molecules
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Author :
language : en
Publisher:
Release Date : 19??
Encyclopedia Of Signaling Molecules written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 19?? with categories.