Lilly S Discovery
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Lilly S Discovery Book One
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Author : Tasha Beuning
language : en
Publisher: Taliro Publishing
Release Date : 2023-09-01
Lilly S Discovery Book One written by Tasha Beuning and has been published by Taliro Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-01 with Fiction categories.
Come along on an amazing journey with Lilly as she embarks on her first grand adventure. With vibrant and captivating images, this book will transport you to a magical world and encourage young minds to explore and learn. Enjoy the amazing illustrations that unfold throughout the story - the illustrator's imagination fully encapsulates the author's intent and combines to make a fully immersive adventure.
Lilly S Discovery
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Author : Robert Beuning
language : en
Publisher:
Release Date : 2023-09
Lilly S Discovery written by Robert Beuning and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09 with categories.
In a world where superpowers collide with sinister experiments, a young girl named Lilly has her whole life turned upside down and her only salvation comes from one simple act of kindness - changing her life forever¿Lilly and her friends take on a journey that tests their courage, resilience, and friendship. With a loved one held captive by a force of darkness, they are put to the ultimate test. Unraveling the depths of their own strength, they must harness the true potential of their extraordinary gifts. Dive into this thrilling tale of adventure, danger, and the indomitable spirit of a heroic team!
Natural Product Chemistry For Drug Discovery
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Author : Antony D. Buss
language : en
Publisher: Royal Society of Chemistry
Release Date : 2010
Natural Product Chemistry For Drug Discovery written by Antony D. Buss and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
This text provides a comprehensive summary of where natural product chemistry is today in drug discovery. It covers emerging technologies and case studies and is a source of up-to-date information on the topical subject of natural products.
Economics And Management In The Biopharmaceutical Industry In The Usa
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Author : Rachel Kim
language : en
Publisher: Routledge
Release Date : 2018-12-17
Economics And Management In The Biopharmaceutical Industry In The Usa written by Rachel Kim and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-17 with Business & Economics categories.
From a managerial perspective, the biopharmaceutical industry represents a competitive, fast-changing, intellectually-powered, innovation-driven sector. Many management scholars have studied this discontinuous era to make sense of strategic behavior and the cognition of firms and top managers. A past look at the biopharmaceutical industry provides answers to questions that most managers have. For example, what options do you have and what actions do you take when new firms enter your industry? In the 1970s, new biotechnology firms, funded by venture capitalists, appeared in the pharmaceutical industry with new knowledge. Successful pharmaceutical firms decided to collaborate with the new entrants and forge relationships to develop and create new, biotechnology engineered drugs. Thus, the addition of new biotechnology firms ushered in a new business model based on strategic alliances. Strategic alliances have now become an industrial norm called open innovation. The author looks at the historical path of the biopharmaceutical industry, particularly in the United States. While the pharmaceutical industry’s main contributions to society are substantial, there are pressing challenges the industry must face, such as an increase in infectious disease outbreaks or the global aging population, which require new types of care, additionally, mental health care and prescription painkiller addiction are persistent issues with economic repercussions to both federal and local governments. This book presents a holistic view of the biopharmaceutical industry, putting it in a historical context. It will best serve those who are eager to learn about this dynamic, fast-evolving industry and who would like to tackle current biopharmaceutical industry issues in the United States and be prepared for future industry challenges.
Textbook Of Drug Design And Discovery
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 2002-08-01
Textbook Of Drug Design And Discovery written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-08-01 with Medical categories.
Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lea
Antibiotic Discovery And Development
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Author : Thomas J. Dougherty
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-21
Antibiotic Discovery And Development written by Thomas J. Dougherty and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-21 with Medical categories.
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
Discovering And Developing Molecules With Optimal Drug Like Properties
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Author : Allen C Templeton
language : en
Publisher: Springer
Release Date : 2014-10-31
Discovering And Developing Molecules With Optimal Drug Like Properties written by Allen C Templeton and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-31 with Medical categories.
This authoritative volume provides a contemporary view on the latest research in molecules with optimal drug-like properties. It is a valuable source to access current best practices as well as new research techniques and strategies. Written by leading scientists in their fields, the text consists of fourteen chapters with an underlying theme of early collaborative opportunities between pharmaceutical and discovery sciences. The book explores the practical realities of performing physical pharmaceutical and biopharmaceutical research in the context of drug discovery with short timelines and low compound availability. Chapters cover strategies and tactics to enable discovery as well as predictive approaches to establish, understand and communicate risks in early development. It also examines the detection, characterization, and assessment of risks on the solid state properties of advanced discovery and early development candidates, highlighting the link between solid state properties and critical development parameters such as solubility and stability. Final chapters center on techniques to improve molecular solubilization and prevent precipitation, with particularly emphasis on linking physiochemical properties of molecules to formulation selection in preclinical and clinical settings.
Lead Generation
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Author : Jörg Holenz
language : en
Publisher: John Wiley & Sons
Release Date : 2016-03-16
Lead Generation written by Jörg Holenz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-16 with Medical categories.
In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies in industrial and academic lead generation. This is the first book to combine both standard and innovative approaches in comparable breadth and depth, including several recent successful lead generation case studies published here for the first time. Beginning with a general discussion of the underlying principles and strategies, individual lead generation approaches are described in detail, highlighting their strengths and weaknesses, along with all relevant bordering disciplines like e.g. target identification and validation, predictive methods, molecular recognition or lead quality matrices. Novel lead generation approaches for challenging targets like DNA-encoded library screening or chemical biology approaches are treated here side by side with established methods as high throughput and affinity screening, knowledge- or fragment-based lead generation, and collaborative approaches. Within the entire book, a very strong focus is given to highlight the application of the presented methods, so that the reader will be able to learn from real life examples. The final part of the book presents several lead generation case studies taken from different therapeutic fields, including diabetes, cardiovascular and respiratory diseases, neuroscience, infection and tropical diseases. The result is a prime knowledge resource for medicinal chemists and for every scientist involved in lead generation.
The Never Ending Revival
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Author : Michael F. Scully
language : en
Publisher: University of Illinois Press
Release Date : 2022-08-15
The Never Ending Revival written by Michael F. Scully and has been published by University of Illinois Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-15 with Music categories.
In recent years, there has been an upsurge in interest in "roots music" and "world music," popular forms that fuse contemporary sounds with traditional vernacular styles. In the 1950s and 1960s, the music industry characterized similar sounds simply as "folk music." Focusing on such music since the 1950s, The Never-Ending Revival: Rounder Records and the Folk Alliance analyzes the intrinsic contradictions of a commercialized folk culture. Both Rounder Records and the North American Folk Music and Dance Alliance have sought to make folk music widely available, while simultaneously respecting its defining traditions and unique community atmosphere. By tracing the histories of these organizations, Michael F. Scully examines the ongoing controversy surrounding the profitability of folk music. He explores the lively debates about the difficulty of making commercially accessible music, honoring tradition, and remaining artistically relevant, all without "selling out." In the late 1950s through the 1960s, the folk music revival pervaded the mainstream music industry, with artists such as Bob Dylan and Joan Baez singing historically or politically informed ballads based on musical forms from Appalachia and the South. In the twenty-first century, the revival continues, and it includes a variety of music derived from Cajun, African American, and Mexican traditions, among many others. Even though the mainstream music industry and media largely ignore the term "folk music," a strong allure based on nostalgia, the desire for community, and a sense of exclusiveness augments an enthusiastic following connected by word-of-mouth, numerous festivals, and the Internet. There are more folk festivals now than there were during the original boom of the 1960s, suggesting that music artists, agents, and record label representatives are striking a successful balance between tradition and profitability. Scully combines rich interviews of music executives and practicing folk musicians with valuable personal experience to reveal how this American subculture remains in a "never-ending revival" based on fluid definitions of folk and folk music.
Contemporary Accounts In Drug Discovery And Development
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Author : Xianhai Huang
language : en
Publisher: John Wiley & Sons
Release Date : 2022-03-11
Contemporary Accounts In Drug Discovery And Development written by Xianhai Huang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-11 with Medical categories.
CONTEMPORARY ACCOUNTS IN DRUG DISCOVERY AND DEVELOPMENT A useful guide for medicinal chemists and pharmaceutical scientists Drug discovery is a lengthy and complex process that typically involves identifying an unmet medical need, determining a biological target, chemical library screening to identify a lead, chemical optimization, preclinical studies and clinical trials. This process often takes many years to complete, and relies on practitioners’ knowledge of chemistry and biology, but also—and perhaps more importantly—on experience. Improving the success rate in discovery and development through a thorough knowledge of drug discovery principles and advances in technology is critical for advancement in the field. Contemporary Accounts in Drug Discovery and Development provides drug discovery scientists with the knowledge they need to quickly gain mastery of the drug discovery process. A thorough accounting is given for each drug covered within the book, as the authors provide pharmacology, drug metabolism, biology, drug development, and clinical studies for every case, with modern drug discovery principles and technologies incorporated throughout. Contemporary Accounts in Drug Discovery and Development readers will also find Case histories used as an engaging way of learning about the drug discovery/development process Detailed biological rational and background information, drug design principles, SAR development, ADMET considerations, and clinical studies The full history of individual marketed small molecule drugs Coverage of drug candidates that have passed Phase I clinical trials with different modalities, such as antibody drug conjugates (ADC), proteolysis-targeting chimera (PROTAC), and peptide drugs The application of new technologies in drug discovery such as DNA-encoded libraries (DEL), positron emission tomography (PET), and physics-based computational modeling employing free energy perturbation (FEP) Contemporary Accounts in Drug Discovery and Development is a helpful tool for medicinal chemists, organic chemists, pharmacologists, and other scientists in drug research and process development. It may be considered essential reading for graduate courses in drug discovery, medicinal chemistry, drug synthesis, pharmaceutical science, and pharmacology. It is also a useful resource for pharmaceutical industry labs, as well as for libraries.