Lipobiology

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Advances In Lipobiology Volume 1

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Author : R.W. Gross
language : en
Publisher: Elsevier
Release Date : 1996-09-24

Advances In Lipobiology Volume 1 written by R.W. Gross and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-09-24 with Science categories.

Lipobiology is an interdisciplinary field which incorporates critical aspects of lipid and lipoprotein chemistry into the disciplines of cell biology and physiology. During the last decade, advances in our understanding of the structure and function of lipids, biological membranes and lipid-derived second messengers have underscored the importance of lipids in the regulation of cellular function. This series focuses on salient aspects of the role of lipids in metabolic regulation and cellular activation, with emphasis on emerging concepts and technologies. One goal of this series is to formulate cohesive criteria upon which a foundation for the evaluation of recent work can be based and future directions of research identified.

Lipobiology

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Author : G. J. van der Vusse
language : en
Publisher: Gulf Professional Publishing
Release Date : 2004

Lipobiology written by G. J. van der Vusse and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Electronic books categories.

Advances In Lipobiology

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Author : R.W. Gross
language : en
Publisher: Elsevier
Release Date : 1997-10-21

Advances In Lipobiology written by R.W. Gross and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-21 with Science categories.

Advances in Lipobiology, Volume 2

Advances In Lipobiology

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Author : Richard W. Gross
language : en
Publisher:
Release Date : 2000-04

Advances In Lipobiology written by Richard W. Gross and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04 with Science categories.

Lipobiology is a rapidly evolving interdisciplinary field which incorporates critical aspects of lipid and lipoprotein chemistry into the disciplines of cell biology and physiology. This series focuses on salient aspects of the role of lipids in metabolic regulation and cellular activation.

Advances In Lipobiology Volume 2

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Author : R.W. Gross
language : en
Publisher: Elsevier Science
Release Date : 1997-10-21

Advances In Lipobiology Volume 2 written by R.W. Gross and has been published by Elsevier Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-21 with Science categories.

Advances In Lipobiology

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Author : R.W. Gross
language : en
Publisher: Elsevier Science
Release Date : 1997-11-04

Advances In Lipobiology written by R.W. Gross and has been published by Elsevier Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-11-04 with Science categories.

Cell Cycle

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Author : Michael Whitaker
language : en
Publisher: Elsevier
Release Date : 1996-03-20

Cell Cycle written by Michael Whitaker and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-03-20 with Science categories.

There has been an enormous advance in our understanding of the regulation of the cell division cycle in the last five years. The leap in understanding has centered on the cell cycle control protein p34cdc2 and its congeners and on the cyclins. The most important insight to emerge has been that cell cycle control mechanisms and their participating proteins are very well-conserved through evolution. This has created a spectacular growth in knowledge as data from one organism have been readily applied to another. In this volume, there are sea urchin and frog eggs, as well as mammalian cells and yeast. There is also an illustration of how fruitful the genetic approach can be in other organisms than yeast with a chapter on Aspergillus nidulans. The cell cycle kinase has been well-characterized and has also been well-exposed in numerous proceedings volumes and collections. In this issue of Advances in Molecular Cell Biology, the cell cycle kinase is ever present, but in the early chapters it has a supporting role. Center stage are the regulatory mechanisms that control the kinase. The contribution that the centrosome (the organelle of cell division) makes to cell cycle regulation are described. The part played by calcium and calcium-controlled regulatory proteins is emphasized. The importance of phosphatase as well as kinase activity to cell cycle regulation is stressed. The last words are reserved for the mitotic kinase: the last chapters describe its effects and its regulation in cell-free systems.

Cell Chemistry And Physiology

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Author : Edward Bittar
language : en
Publisher: Elsevier
Release Date : 1996-01-04

Cell Chemistry And Physiology written by Edward Bittar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-04 with Science categories.

This is the first of a 4-volume module that is an introduction to the study of cell chemistry and physiology. It is not intended to be encyclopedic in nature but rather a general survey of the subject with an emphasis on those topics that are central to an understanding of cell biology and those that are certain to become of increasing importance in the teaching of modern medicine. We have followed what appeared to as to be the logical divisions of the subject beginning with proteins. Allewell and her colleagues stress the point that proteins fold spontaneously to form complex three-dimensional structures and that some of them unfold with the help of proteins called chaperones. Michaelis-Menten kinetics are shown by Nelsestuen to describe the behaviour of enzymes in the test tube. The formalism is particularly useful in the search for agents of therapeutic value, as exemplified by methotrexate. Uptake by mammalian cells of substrates and their metabolic conversions are discussed by van der Vusse and Reneman. However, both Welch and Savageau expound the view that the cell is not simply a bagful of enzymes. The biologist is urged by Savageau to abandon Michaelis-Menten formalism and apply the Power Law. The biologist is also told that the approach to arriving at a theory of metabolic control would have to be one of successive approximations requiring the use of the computer. Information gained from comparative biochemistry is shown by Storey and Brooks to have shed new light on mechanisms of metabolic rate depression and freeze tolerance, and to be applicable to organ transplantation technology. We are reminded that enzyme adaptation is partly the result of the presence of a hydrating shell of vicinal water that stabilises conformation of the enzyme. Vicinal water, according to Drost-Hausen and Singleton, lies adjacent to most solids and protein interfaces. The kinks or breaks observed in the slope of the Arrhenius plot are attributed to structural changes in vicinal water. Regulation of cell volume is shown by Hempling to involve regulation of cell water. It could be that the osmo-receptor or volume detection system is a protein that links the cytoskeleton to specific K and C1 channels. Additionally, it is interesting that aquaporins, which are water channel-forming membrane proteins, are now known to exist in both renal and extra-renal tissues. One of the renal porins is affected by vasopressin. We then pass on to protein synthesis (Rattan) and other important topics including protein glycosylation (Hounsell), methylation (Clarke), ADP-ribosylation (Pearson) and prenylation (Gelb). Among the four types of lipids attached to membrane proteins are the prenyl groups. Ford and Gross in their chapter on lipobiology drive home the point that there is an accumulation of acyl carnitine and lysophospholipids during myocardial infarction.

Chemistry Of The Living Cell

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Author : E. Edward Bittar
language : en
Publisher: JAI Press(NY)
Release Date : 1992

Chemistry Of The Living Cell written by E. Edward Bittar and has been published by JAI Press(NY) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.

Volumes 3A and 3B aim to give the reader a short but exciting account of the rudiments of cell biology from a largely chemical point of view. Several important topics, however, such as membrane and organelle biochemistry and cellular signalling are dealt with in later volumes. The problems of enzyme organization in situ, metabolic compartmentation, organelle interactions, and nuclear-cytoplasmic interactions are complex and of such magnitude as to continue to defy solution. "Biology is," after all, as John B. Haldane wrote, "not part of physics and chemistry, but moving on a higher plane than they do - higher because biological interpretation is a truer representation of the reality which appears to us in our experience.

Cell Chemistry And Physiology

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Author : Edward Bittar
language : en
Publisher: Elsevier
Release Date : 1996-05-14

This volume illustrates the extent to which the traditional distinction between biochemical and physiological processes is being obliterated by molecular biology. It can hardly be doubted that the revolution in cell and molecular biology is leading to core knowledge that provides an outline of the integrative and reductionist approach. We view this as the beginning of a new era, that of the integration of learning. As in the preceding volumes, the choice of topics has been deliberate not only because of the need to keep the volume within reasonable bounds but also because of the need to avoid information over-load. Several relevant topics are dealt with in other modules; for example, the role of G proteins in transmembrane signalling is covered in the Membranes and Cell Signalling module (i.e., Volume 7). Omissions are of course inevitable but they are minor. A case in point is the subject of phosphatases, the treatment of which does not take into account calcineurin. One of the key functions of this Ca2+ -activated protein phosphatase that is also regulated by calmodulin is to desphosphorylate voltage-dependent Ca2+ channels. The mere recognition of such omissions before or after consulting textbooks and journals should be a spur to a more complete discussion by the student of the subject in a small group teaching setting.

Lipobiology

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