Liposomes In Contact And Interacting With Silica Nanoparticles From Decorated Vesicles To Internalized Particles
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Liposomes In Contact And Interacting With Silica Nanoparticles From Decorated Vesicles To Internalized Particles
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Author : Raphael Michel
language : en
Publisher: Cuvillier Verlag
Release Date : 2013-12-16
Liposomes In Contact And Interacting With Silica Nanoparticles From Decorated Vesicles To Internalized Particles written by Raphael Michel and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-16 with Science categories.
In the past few years, growing attention has been devoted to the study of the interactions taking place in mixed systems of phospholipid membranes and inorganic nanoparticles. This is an important issue with regard to using nanoparticles in nanomedicine but also in the related field of nanotoxicology. However, the nature of the interactions in such mixtures is rather complex and may lead to the formation of different colloidal structures. Focusing on the case of liposomes and silica nanoparticles, the study presented here aims at improving our understanding of the interactions in such mixed systems and at obtaining a detailed picture of the hybrid structures they result in. Drawing a parallel between different systems, this work offers not only interesting features on the internalization process of nanoparticles and on the stability of nanoparticle–decorated vesicles but also comprehensive insights into the influence of the bilayer state (liquid, gel) on the nanoscale structures of hybrid liposome/nanoparticle complexes.
Liposomes In Contact And Interacting With Silica Nanoparticles From Decorated Vesicles To Internalized Particles
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Author : Raphael Michel
language : en
Publisher:
Release Date : 2013
Liposomes In Contact And Interacting With Silica Nanoparticles From Decorated Vesicles To Internalized Particles written by Raphael Michel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
Computational Nanotoxicology
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Author : Agnieszka Gajewicz
language : en
Publisher: CRC Press
Release Date : 2019-11-13
Computational Nanotoxicology written by Agnieszka Gajewicz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-13 with Medical categories.
The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of engineered nanoparticles, computational methods originally developed for regular (i.e., classic) chemicals cannot always be applied explicitly in nanotoxicology. Thus, the main idea of this book is to discuss the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. The book focuses on methodology. Among various in silico techniques, special attention is given to (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics); (ii) nanochemoinformatic methods (quantitative structure–activity relationship modeling, grouping, read-across); and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics).
Oral Lipid Based Formulations
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Author : David J. Hauss
language : en
Publisher: CRC Press
Release Date : 2007-06-08
Oral Lipid Based Formulations written by David J. Hauss and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-08 with Medical categories.
Oral lipid-based formulations are attracting considerable attention due to their capacity to facilitate gastrointestinal absorption and reduce or eliminate the effect of food on the absorption of poorly water-soluble, lipophilic drugs. Despite the obvious and demonstrated utility of these formulations for addressing a persistent and growing problem
Polymer Nanoparticles For Nanomedicines
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Author : Christine Vauthier
language : en
Publisher: Springer
Release Date : 2017-01-07
Polymer Nanoparticles For Nanomedicines written by Christine Vauthier and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-07 with Medical categories.
This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.
Nanotoxicology
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Author : Nelson Durán
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-25
Nanotoxicology written by Nelson Durán and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-25 with Medical categories.
This book takes a systematic approach to nanotoxicology and the developing risk factors associated with nanosized particles during manufacture and use of nanotechnology. Beginning with a detailed introduction to engineered nanostructures, the first part of the book presents concepts and definitions of nanomaterials from quantum dots to graphene to fullerenes, with detailed discussion of functionalization, stability, and medical and biological applications. The second part critically examines methodologies used to assess cytotoxicity and genotoxicity. Coverage includes interactions with blood (erythrocytes), combinatorial and microarray techniques, cellular mechanisms, and ecotoxicology assessments. Part three describes cases studies both in vitro and in vivo for specific nanomaterials including solid lipid nanoparticles and nanostructured lipid carriers and metallic nanoparticles and metallic oxides. New information is also presented on toxicological aspects of poloxamers and polymeric nanoparticles as drug carriers as well as size effects on cytotoxicity and genotoxicity. Didactic aspects are emphasized in all chapters, making the book suitable for a broad audience ranging from advanced undergraduate and graduate students to researchers in academia and industry. In all, Nanotoxicology: Materials, Methodologies, and Assessments will provide comprehensive insight into biological and environmental interactions with nanostructures. Provides an introduction to nanostructures actually in use Describes cyto- and genotoxicity methodologies, and assesses their performance in comparison to common toxicity assays Discusses the relation of cytotoxicity and genotoxicity to ecotoxicity Presents a range of applications, from biogenic silver nanoparticles to poloxamers as drug-delivery systems, reflecting the expanding applications of nanotechnology
The Giant Vesicle Book
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Author : Rumiana Dimova
language : en
Publisher: CRC Press
Release Date : 2019-11-19
The Giant Vesicle Book written by Rumiana Dimova and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-19 with Science categories.
Giant vesicles are widely used as a model membrane system, both for basic biological systems and for their promising applications in the development of smart materials and cell mimetics, as well as in driving new technologies in synthetic biology and for the cosmetics and pharmaceutical industry. The reader is guided to use giant vesicles, from the formation of simple membrane platforms to advanced membrane and cell system models. It also includes fundamentals for understanding lipid or polymer membrane structure, properties and behavior. Every chapter includes ideas for further applications and discussions on the implications of the observed phenomena towards understanding membrane-related processes. The Giant Vesicle Book is meant to be a road companion, a trusted guide for those making their first steps in this field as well as a source of information required by experts. Key Features • A complete summary of the field, covering fundamental concepts, practical methods, core theory, and the most promising applications • A start-up package of theoretical and experimental information for newcomers in the field • Extensive protocols for establishing the required preparations and assays • Tips and instructions for carefully performing and interpreting measurements with giant vesicles or for observing them, including pitfalls • Approaches developed for investigating giant vesicles as well as brief overviews of previous studies implementing the described techniques • Handy tables with data and structures for ready reference
The Giant Vesicle Book
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Author : Rumiana Dimova
language : en
Publisher: CRC Press
Release Date : 2019-11-19
The Giant Vesicle Book written by Rumiana Dimova and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-19 with Science categories.
Giant vesicles are widely used as a model membrane system, both for basic biological systems and for their promising applications in the development of smart materials and cell mimetics, as well as in driving new technologies in synthetic biology and for the cosmetics and pharmaceutical industry. The reader is guided to use giant vesicles, from the formation of simple membrane platforms to advanced membrane and cell system models. It also includes fundamentals for understanding lipid or polymer membrane structure, properties and behavior. Every chapter includes ideas for further applications and discussions on the implications of the observed phenomena towards understanding membrane-related processes. The Giant Vesicle Book is meant to be a road companion, a trusted guide for those making their first steps in this field as well as a source of information required by experts. Key Features • A complete summary of the field, covering fundamental concepts, practical methods, core theory, and the most promising applications • A start-up package of theoretical and experimental information for newcomers in the field • Extensive protocols for establishing the required preparations and assays • Tips and instructions for carefully performing and interpreting measurements with giant vesicles or for observing them, including pitfalls • Approaches developed for investigating giant vesicles as well as brief overviews of previous studies implementing the described techniques • Handy tables with data and structures for ready reference
Nanomedicines
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Author : Martin Braddock
language : en
Publisher: Royal Society of Chemistry
Release Date : 2016-04-14
Nanomedicines written by Martin Braddock and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-14 with Science categories.
Nanomedicines and nanopharmacology is a rapidly developing and evolving field with new techniques and applications under constant development. This book will provide an overview of the chemistry of nanocarrier design and the considerations that need to be made when developing a nanomedicine. Providing an understanding of the relationship of nanocarrier, drug and targetting moieties and physico-chemical properties, this title will provide an accurate and current representation of the field by addressing the promises, prospects and pitfalls of nanomedicine. Covering a wide range of areas in detail, this book will provide an excellent companion for medicinal chemists, pharmacologists and biochemists working in industry or academia.
Biomimetics
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Author : Amitava Mukherjee
language : en
Publisher: BoD – Books on Demand
Release Date : 2010-03-01
Biomimetics written by Amitava Mukherjee and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-01 with Medical categories.
Nature’s evolution has led to the introduction of highly efficient biological mechanisms. Imitating these mechanisms offers an enormous potential for the improvement of our day to day life. Ideally, by bio-inspiration we can get a better view of nature’s capability while studying its models and adapting it for our benefit. This book takes us into the interesting world of biomimetics and describes various arenas where the technology is applied. The 25 chapters covered in this book disclose recent advances and new ideas in promoting the mechanism and applications of biomimetics.