Lung Cancer And Personalized Medicine
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Lung Cancer And Personalized Medicine Novel Therapies And Clinical Management
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Author : Aamir Ahmad
language : en
Publisher: Springer
Release Date : 2015-12-24
Lung Cancer And Personalized Medicine Novel Therapies And Clinical Management written by Aamir Ahmad and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-24 with Medical categories.
This, the second of two volumes on personalized medicine in lung cancer, touches upon the recent progress in targeted drug development based on genomics; emerging biomarkers and therapeutic targets such as EMT, cancer stem cells, and the tumor microenvironment; current personalized clinical management and radiation therapy for lung cancers; and the promise of epigenetics and next-generation sequencing for the advancements towards personalized therapy of lung cancer patients. With chapters on state-of-the-art therapies and technologies written by leading experts working to develop novel companion diagnosis tools for the personalized treatment of lung cancer patients, this volume brings readers up-to-date by presenting the current knowledge on the efforts to make personalized management of lung cancer patients a reality.
Lung Cancer And Personalized Medicine
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Author : Aamir Ahmad
language : en
Publisher: Springer
Release Date : 2015-12-14
Lung Cancer And Personalized Medicine written by Aamir Ahmad and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-14 with Medical categories.
This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.
Lung Cancer And Personalized Medicine
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Author :
language : en
Publisher:
Release Date : 2016
Lung Cancer And Personalized Medicine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Lungs categories.
This, the second of two volumes on personalized medicine in lung cancer, touches upon the recent progress in targeted drug development based on genomics; emerging biomarkers and therapeutic targets such as EMT, cancer stem cells, and the tumor microenvironment; current personalized clinical management and radiation therapy for lung cancers; and the promise of epigenetics and next-generation sequencing for the advancements towards personalized therapy of lung cancer patients. With chapters on state-of-the-art therapies and technologies written by leading experts working to develop novel companion diagnosis tools for the personalized treatment of lung cancer patients, this volume brings readers up-to-date by presenting the current knowledge on the efforts to make personalized management of lung cancer patients a reality.
Update On The Treatment Of Metastatic Non Small Cell Lung Cancer Nsclc In New Era Of Personalised Medicine
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Author : Vera Hirsh
language : en
Publisher: Frontiers Media SA
Release Date : 2018-01-24
Update On The Treatment Of Metastatic Non Small Cell Lung Cancer Nsclc In New Era Of Personalised Medicine written by Vera Hirsh and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-24 with categories.
Lung cancer remains a major cause of death in of both women and men in our society. Lung cancer treatment paradigms have changed enormously as we’ve started to understand the genetic complexity and the multiple driver mutations influencing the disease. Therapeutics directed towards, or to inhibit signaling pathways has resulted in increased life spans for our patients. Over the last two decades, we have gone from simple chemotherapy used to treat all, to a personalized medicine approach for the majority. For non-small cell lung cancer patients without driver mutations, the world of immune oncology has arrived. These improved long-term outcomes mean that now our lung cancer patients can live with their cancers, but without progression. The aim of this book is to catalogue the current state of knowledge for the many facets of advanced lung cancer. It describes current treatment approaches for driver mutations, rare mutations, and rare thoracic malignancies such as neuroendocrine tumors. Most importantly, this book addresses the topics of palliative treatment and care which allow our patients to enjoy longer survival with the highest quality of life. We hope you enjoy this e-book. The future is brighter for lung cancer patients and as lung cancer specialists; we finally feel sense optimism about treatment options for our patients.
The Treatment Of Metastatic Non Small Cell Lung Cancer Nsclc In New Era Of Personalised Medicine
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Author : Vera Hirsh
language : en
Publisher: Frontiers Media SA
Release Date : 2015-10-20
The Treatment Of Metastatic Non Small Cell Lung Cancer Nsclc In New Era Of Personalised Medicine written by Vera Hirsh and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-20 with Medicine (General) categories.
Lung cancer is the leading cause of cancer related mortality in Canada and USA. Majority of the patients present in advanced stage of the disease and of these only about 2% will be alive at 5 years. NSCLC is the most common form of lung cancer, accounting for approximately 87% of cases. Systemic chemotherapies have been used to treat metastatic NSCLC for decades, but the improvements of outcomes have reached a plateau. Recent advances in understanding signalling pathways for malignant cells, their interconections,the importance of various receptors and biomarkers and the interplay between various oncogenes have led to the development of targeted treatments that are improving both efficacy and safety of the treatments. Knowledge about the advantages of treatments with the targeted agents in metastatic NSCLC is growing rapidly. Combining various targeted agents or sequencing them properly will be important in the era of personalised medicine and overcoming development of the resistence to various targeted agents will be challenging. The importance of a team work,from the diagnosis through various treatments, to supportive care, from the interventional radiologists, pneumologists or surgeons, who have to obtain a satisfactory tumor tissue specimen, to pathologists, radiation and medical oncologists, to supportive care specialists, will be described in our publications. We will cover completely present and future approaches to personalised medicine in this rapidly evolving field of metastatic NSCLC.
Update On The Treatment Of Metastatic Non Small Cell Lung Cancer Nsclc In New Era Of Personalised Medicine
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Author :
language : en
Publisher:
Release Date : 2018
Update On The Treatment Of Metastatic Non Small Cell Lung Cancer Nsclc In New Era Of Personalised Medicine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Lung Cancer remains a major cause of death in of both women and men in our society. Lung cancer treatment paradigms have changed enormously as we've started to understand the genetic complexity and the multiple driver mutations influencing the disease. Therapeutics directed towards, or to inhibit signaling pathways has resulted in increased life spans for our patients. Over the last two decades, we have gone from simple chemotherapy used to treat all, to a personalized medicine approach for the majority. For non-small cell lung cancer patients without driver mutations, the world of immune oncology has arrived. These improved long-term outcomes mean that now our lung cancer patients can live with their cancers, but without progression. The aim of this book is to catalogue the current state of knowledge for the many facets of advanced lung cancer. It describes current treatment approaches for driver mutations, rare mutations, and rare thoracic malignancies such as neuroendocrine tumors. Most importantly, this book addresses the topics of palliative treatment and care which allow our patients to enjoy longer survival with the highest quality of life. We hope you enjoy this e-book. The future is brighter for lung cancer patients and as lung cancer specialists; we finally feel sense optimism about treatment options for our patients.
Precision Medicine In Cancer Therapy
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Author : Daniel D. Von Hoff
language : en
Publisher: Springer
Release Date : 2019-06-17
Precision Medicine In Cancer Therapy written by Daniel D. Von Hoff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-17 with Medical categories.
This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.
Targeted Therapies In Lung Cancer Management Strategies For Nurses And Practitioners
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Author : Marianne Davies
language : en
Publisher: Springer
Release Date : 2019-07-16
Targeted Therapies In Lung Cancer Management Strategies For Nurses And Practitioners written by Marianne Davies and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-16 with Medical categories.
This book aims to educate nurses and advanced practice providers (APP’s) about known mutations, availability of targeted therapy and the management of patients with non-small cell lung cancer (NSCLC). It will educate nurses and practitioners about the scope of therapy to assure safe and effective lung cancer treatment. In this era of personalized medicine, nurses and APP’s are responsible for guiding patients from diagnosis through treatment. This starts with the identification of patients that can benefit from these therapies, the key role of biopsy acquisition (ie. what to test, when and how often) and treatment selection based on the mutation identified. Readers will learn about the mechanisms of action, administration, potential adverse side effects and unique management strategies for these targeted agents. Lung cancer continues to be the leading cause of cancer death in the United States and worldwide. Recent advances in the identification of specific oncogenic mutations that drive cancer development, growth and metastasis have led to major paradigm shifts in lung cancer treatment. Sophisticated methods are required to identify specific mutations at the time of diagnosis. This book explains how molecularly targeted therapies have been developed that target these drivers. To date, several tyrosine kinase inhibitors have been approved to target the epidermal growth factor receptor (EGFR), EML4-ALK ,ROS1 and BRAF. Most recently, immune checkpoint inhibitors have been approved with some indication that efficacy may be enhanced for patients who overexpress PD-L1. While some driver mutations have been identified, there is ongoing investigation into additional mutations. In the case of driver mutations, lung cancers will develop resistance to therapy. This book provides nurses and APP’s with the mechanisms of resistance that have been identified such as T790 mutation and many others in the EGFR mutation, and shows how the next level of drug development is focused on identifying mechanisms of resistance and development of new agents that overcome these mutations. With this book in hand, nurses and practitioners will be able to navigate patients through this ever expanding field of lung cancer treatment.
Lung Cancer Unveiled From Research To Personalized Care
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Author : Dr. Spineanu Eugenia
language : en
Publisher: Dr. Spineanu Eugenia
Release Date : 2024-03-03
Lung Cancer Unveiled From Research To Personalized Care written by Dr. Spineanu Eugenia and has been published by Dr. Spineanu Eugenia this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-03 with Medical categories.
Unlock the secrets of lung cancer in "Lung Cancer Unveiled: From Research to Personalized Care." Delve into the world of cutting-edge research, revolutionary treatments, and the global efforts that are reshaping the landscape of lung cancer care. In this comprehensive treatise, you'll embark on a journey through the intricate web of lung cancer, exploring its multifaceted nature and the global collaborations that are driving progress. Discover how epidemiology and risk factors play a pivotal role in shaping the incidence of lung cancer and how early detection technologies are transforming the odds for patients. With a focus on personalized treatment approaches, this treatise unveils the power of precision medicine in lung cancer care. Explore genetic profiling, molecular biomarkers, and immunotherapy innovations that are redefining how we combat this deadly disease. Learn how personalized treatment strategies are offering patients not just hope, but real outcomes that extend survival and enhance quality of life. But "Lung Cancer Unveiled" goes beyond the science. It delves into the global efforts, advocacy, and healthcare policies that are shaping the future of lung cancer care. Gain insights into the collaborative initiatives, research advancements, and challenges that researchers, clinicians, and organizations worldwide are tackling head-on. If you seek knowledge, hope, and actionable insights into lung cancer, this treatise is your comprehensive guide. With its SEO-optimized content, it's designed not just to inform but also to reach those who need it most. Join us on this journey through the world of lung cancer research, and discover how we're unveiling a brighter future for patients and their families.
Lung Cancer
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Author : Henry S. Park
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-06-02
Lung Cancer written by Henry S. Park and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-02 with Medical categories.
Lung cancer continues to be the leading cause of cancer mortality worldwide among both men and women. Recent advances in prevention, screening and management in the past decade have led to significant improvements in survival and quality of life. Local treatments like minimally invasive surgery, radiotherapy, and image-guided ablation have contributed to improving the effectiveness and tolerability of potentially curative treatments in early-stage, locally advanced, and oligometastatic/oligoprogressive disease. Chemotherapy, targeted therapy, immunotherapy, and palliative local therapy options have expanded rapidly, with new regimens showing improved outcomes even for those with widely metastatic disease. This book comprehensively reviews the evidence that has driven personalized medicine, based on a variety of multidisciplinary perspectives by international lung cancer experts.