Machine Learning Based Sequence Analysis Bioinformatics And Nanopore Transduction Detection
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Machine Learning Based Sequence Analysis Bioinformatics And Nanopore Transduction Detection
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Author : Stephen Winters-Hilt
language : en
Publisher: Lulu.com
Release Date : 2011-05-01
Machine Learning Based Sequence Analysis Bioinformatics And Nanopore Transduction Detection written by Stephen Winters-Hilt and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-01 with Computers categories.
This is intended to be a simple and accessible book on machine learning methods and their application in computational genomics and nanopore transduction detection. This book has arisen from eight years of teaching one-semester courses on various machine-learning, cheminformatics, and bioinformatics topics. The book begins with a description of ad hoc signal acquisition methods and how to orient on signal processing problems with the standard tools from information theory and signal analysis. A general stochastic sequential analysis (SSA) signal processing architecture is then described that implements Hidden Markov Model (HMM) methods. Methods are then shown for classification and clustering using generalized Support Vector Machines, for use with the SSA Protocol, or independent of that approach. Optimization metaheuristics are used for tuning over algorithmic parameters throughout. Hardware implementations and short code examples of the various methods are also described.
Informatics And Machine Learning
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Author : Stephen Winters-Hilt
language : en
Publisher: John Wiley & Sons
Release Date : 2022-01-06
Informatics And Machine Learning written by Stephen Winters-Hilt and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-06 with Mathematics categories.
Informatics and Machine Learning Discover a thorough exploration of how to use computational, algorithmic, statistical, and informatics methods to analyze digital data Informatics and Machine Learning: From Martingales to Metaheuristics delivers an interdisciplinary presentation on how analyze any data captured in digital form. The book describes how readers can conduct analyses of text, general sequential data, experimental observations over time, stock market and econometric histories, or symbolic data, like genomes. It contains large amounts of sample code to demonstrate the concepts contained within and assist with various levels of project work. The book offers a complete presentation of the mathematical underpinnings of a wide variety of forms of data analysis and provides extensive examples of programming implementations. It is based on two decades worth of the distinguished author’s teaching and industry experience. A thorough introduction to probabilistic reasoning and bioinformatics, including Python shell scripting to obtain data counts, frequencies, probabilities, and anomalous statistics, or use with Bayes’ rule An exploration of information entropy and statistical measures, including Shannon entropy, relative entropy, maximum entropy (maxent), and mutual information A practical discussion of ad hoc, ab initio, and bootstrap signal acquisition methods, with examples from genome analytics and signal analytics Perfect for undergraduate and graduate students in machine learning and data analytics programs, Informatics and Machine Learning: From Martingales to Metaheuristics will also earn a place in the libraries of mathematicians, engineers, computer scientists, and life scientists with an interest in those subjects.
Nanopore Sequencing An Introduction
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Author : Daniel Branton
language : en
Publisher: World Scientific
Release Date : 2019-04-05
Nanopore Sequencing An Introduction written by Daniel Branton and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-05 with Science categories.
This is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together with instructional material written by experts that describes how to use a MinION nanopore instrument for sequencing in research or the classroom.At Harvard University the book serves as a textbook and lab manual for a university laboratory course designed to intensify the intellectual experience of incoming undergraduates while exploring biology as a field of concentration. Nanopore sequencing is an ideal topic as a path to encourage students about the range of courses they will take in Biology by pre-emptively addressing the complaint about having to take a course in Physics or Maths while majoring in Biology. The book addresses this complaint by concretely demonstrating the range of topics — from electricity to biochemistry, protein structure, molecular engineering, and informatics — that a student will have to master in subsequent courses if he or she is to become a scientist who truly understands what his or her biology instrument is measuring when investigating biological phenomena.
Bioinformatics For Beginners
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Author : Supratim Choudhuri
language : en
Publisher: Elsevier
Release Date : 2014-05-09
Bioinformatics For Beginners written by Supratim Choudhuri and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-09 with Science categories.
Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. - Avoids non-essential coverage, yet fully describes the field for beginners - Explains the molecular basis of evolution to place bioinformatic analysis in biological context - Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools - Contains over 100 figures that aid in concept discovery and illustration
Plant Signaling Molecules
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Author : M. Iqbal R. Khan
language : en
Publisher: Woodhead Publishing
Release Date : 2019-03-15
Plant Signaling Molecules written by M. Iqbal R. Khan and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-15 with Technology & Engineering categories.
Plant Signaling Molecule: Role and Regulation under Stressful Environments explores tolerance mechanisms mediated by signaling molecules in plants for achieving sustainability under changing environmental conditions. Including a wide range of potential molecules, from primary to secondary metabolites, the book presents the status and future prospects of the role and regulation of signaling molecules at physiological, biochemical, molecular and structural level under abiotic stress tolerance. This book is designed to enhance the mechanistic understanding of signaling molecules and will be an important resource for plant biologists in developing stress tolerant crops to achieve sustainability under changing environmental conditions. - Focuses on plant biology under stress conditions - Provides a compendium of knowledge related to plant adaptation, physiology, biochemistry and molecular responses - Identifies treatments that enhance plant tolerance to abiotic stresses - Illustrates specific physiological pathways that are considered key points for plant adaptation or tolerance to abiotic stresses
Biomedical Applications Of Graphene And 2d Nanomaterials
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Author : Md Nurunnabi
language : en
Publisher: Elsevier
Release Date : 2019-03-31
Biomedical Applications Of Graphene And 2d Nanomaterials written by Md Nurunnabi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-31 with Technology & Engineering categories.
Biomedical Applications of Graphene and 2D Nanomaterials provides a much-needed reference on the biomedical applications of 2D nanomaterials, as well as theoretical knowledge on their structure, physicochemical properties and biomedical applications. Chapters are dedicated to growth areas, such as size and shape-dependent chemical and physical properties and applications, such as in diagnostic and therapeutic products. The book also discusses the concept, development and preclinical studies of 2D nanomaterials-based biomedical tools, such as biosensors, artificial organs and photomedicine. Case studies and reports form the core of the book, making it an ideal resource on potential applications in biomedical science and engineering. This timely resource for scientists and engineers in this rapidly advancing field features contributions from over 30 leaders who address advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials, along with expert opinions on a range of 2D nanomaterials that have therapeutic and diagnostic applications. - Presents advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials - Provides state-of-the-art biomedical applications for 2D nanomaterials, including graphene and boron nitride - Includes key information from a broad selection of subject areas for researchers in both materials, engineering and medicine
Deep Learning In Biology And Medicine
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Author : Davide Bacciu
language : en
Publisher: World Scientific
Release Date : 2022-01-17
Deep Learning In Biology And Medicine written by Davide Bacciu and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-17 with Computers categories.
Biology, medicine and biochemistry have become data-centric fields for which Deep Learning methods are delivering groundbreaking results. Addressing high impact challenges, Deep Learning in Biology and Medicine provides an accessible and organic collection of Deep Learning essays on bioinformatics and medicine. It caters for a wide readership, ranging from machine learning practitioners and data scientists seeking methodological knowledge to address biomedical applications, to life science specialists in search of a gentle reference for advanced data analytics.With contributions from internationally renowned experts, the book covers foundational methodologies in a wide spectrum of life sciences applications, including electronic health record processing, diagnostic imaging, text processing, as well as omics-data processing. This survey of consolidated problems is complemented by a selection of advanced applications, including cheminformatics and biomedical interaction network analysis. A modern and mindful approach to the use of data-driven methodologies in the life sciences also requires careful consideration of the associated societal, ethical, legal and transparency challenges, which are covered in the concluding chapters of this book.
Advances In Bioinformatics
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Author : Vijai Singh
language : en
Publisher: Springer Nature
Release Date : 2021-07-31
Advances In Bioinformatics written by Vijai Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-31 with Science categories.
This book presents the latest developments in bioinformatics, highlighting the importance of bioinformatics in genomics, transcriptomics, metabolism and cheminformatics analysis, as well as in drug discovery and development. It covers tools, data mining and analysis, protein analysis, computational vaccine, and drug design. Covering cheminformatics, computational evolutionary biology and the role of next-generation sequencing and neural network analysis, it also discusses the use of bioinformatics tools in the development of precision medicine. This book offers a valuable source of information for not only beginners in bioinformatics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in many areas.
Concepts In Bioinformatics And Genomics
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Author : Jamil Momand
language : en
Publisher: Oxford University Press, USA
Release Date : 2017
Concepts In Bioinformatics And Genomics written by Jamil Momand and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Bioinformatics categories.
Concepts in Bioinformatics and Genomics takes a conceptual approach, balancing biology, mathematics, and programming while highlighting relevant real-world applications and providing students with the tools to compute and analyze biological data. Through many thought-provoking exercises,students will develop a deeper understanding of the molecular biology, basic probability, software programs, and program-coding methodology underpinning this exciting field.
Omics Technologies And Bio Engineering
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Author : Debmalya Barh
language : en
Publisher: Academic Press
Release Date : 2017-12-01
Omics Technologies And Bio Engineering written by Debmalya Barh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Science categories.
Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care.