Machine Learning For Biological Sequence Analysis

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Machine Learning For Biological Sequence Analysis
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Author : Quan Zou
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-09
Machine Learning For Biological Sequence Analysis written by Quan Zou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-09 with Science categories.
Computational Techniques For Biological Sequence Analysis
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Author : Saiyed Umer
language : en
Publisher: CRC Press
Release Date : 2025-06-17
Computational Techniques For Biological Sequence Analysis written by Saiyed Umer and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-17 with Computers categories.
This book provides an overview of basic and advanced computational techniques for analyzing and understanding protein, RNA, and DNA sequences. It covers effective computing techniques for DNA and protein classifications, evolutionary and sequence information analysis, evolutionary algorithms, and ensemble algorithms. Furthermore, the book reviews the role of machine learning techniques, artificial intelligence, ensemble learning, and sequence-based features in predicting post-translational modifications in proteins, DNA methylation, and mRNA methylation, along with their functional implications. The book also discusses the prediction of protein–protein and protein–DNA interactions, protein structure, and function using computational methods. It also presents techniques for quantitative analysis of protein–DNA interactions and protein methylation and their involvement in gene regulation. Additionally, the use of nature-inspired algorithms to gain insights into gene regulatory mechanisms and metabolic pathways in human diseases is explored. This book acts as a useful reference for bioinformaticians and computational biologists working in the fields of molecular biology, genomics, and bioinformatics. Key Features: Reviews machine learning techniques for DNA sequence classification and protein structure prediction Discusses genetic algorithms for analyzing multiple sequence alignments and predicting protein–protein interaction sites Explores computational methods for quantitative analysis of protein–DNA interactions Examine the role of nature-inspired algorithms in understanding the gene regulation and metabolic pathways Covers evolutionary algorithms and sequence-based features in predicting post-translational modifications
Problems And Solutions In Biological Sequence Analysis
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Author : Mark Borodovsky
language : en
Publisher: Cambridge University Press
Release Date : 2006-09-04
Problems And Solutions In Biological Sequence Analysis written by Mark Borodovsky and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-04 with Science categories.
This book is the first of its kind to provide a large collection of bioinformatics problems with accompanying solutions. Notably, the problem set includes all of the problems offered in Biological Sequence Analysis, by Durbin et al. (Cambridge, 1998), widely adopted as a required text for bioinformatics courses at leading universities worldwide. Although many of the problems included in Biological Sequence Analysis as exercises for its readers have been repeatedly used for homework and tests, no detailed solutions for the problems were available. Bioinformatics instructors had therefore frequently expressed a need for fully worked solutions and a larger set of problems for use on courses. This book provides just that: following the same structure as Biological Sequence Analysis and significantly extending the set of workable problems, it will facilitate a better understanding of the contents of the chapters in BSA and will help its readers develop problem-solving skills that are vitally important for conducting successful research in the growing field of bioinformatics. All of the material has been class-tested by the authors at Georgia Tech, where the first ever MSc degree program in Bioinformatics was held.
Bioinformatics Second Edition
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Author : Pierre Baldi
language : en
Publisher: MIT Press
Release Date : 2001-07-20
Bioinformatics Second Edition written by Pierre Baldi and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-20 with Computers categories.
A guide to machine learning approaches and their application to the analysis of biological data. An unprecedented wealth of data is being generated by genome sequencing projects and other experimental efforts to determine the structure and function of biological molecules. The demands and opportunities for interpreting these data are expanding rapidly. Bioinformatics is the development and application of computer methods for management, analysis, interpretation, and prediction, as well as for the design of experiments. Machine learning approaches (e.g., neural networks, hidden Markov models, and belief networks) are ideally suited for areas where there is a lot of data but little theory, which is the situation in molecular biology. The goal in machine learning is to extract useful information from a body of data by building good probabilistic models—and to automate the process as much as possible. In this book Pierre Baldi and Søren Brunak present the key machine learning approaches and apply them to the computational problems encountered in the analysis of biological data. The book is aimed both at biologists and biochemists who need to understand new data-driven algorithms and at those with a primary background in physics, mathematics, statistics, or computer science who need to know more about applications in molecular biology. This new second edition contains expanded coverage of probabilistic graphical models and of the applications of neural networks, as well as a new chapter on microarrays and gene expression. The entire text has been extensively revised.
Analysis Of Biological Data
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Author : Sanghamitra Bandyopadhyay
language : en
Publisher: World Scientific
Release Date : 2007
Analysis Of Biological Data written by Sanghamitra Bandyopadhyay and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Science categories.
Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers.This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter.
Machine Learning Used In Biomedical Computing And Intelligence Healthcare Volume I
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Author : Honghao Gao
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-17
Machine Learning Used In Biomedical Computing And Intelligence Healthcare Volume I written by Honghao Gao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-17 with Science categories.
Machine Learning In Bioinformatics Of Protein Sequences Algorithms Databases And Resources For Modern Protein Bioinformatics
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Author : Lukasz Kurgan
language : en
Publisher: World Scientific
Release Date : 2022-12-06
Machine Learning In Bioinformatics Of Protein Sequences Algorithms Databases And Resources For Modern Protein Bioinformatics written by Lukasz Kurgan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Science categories.
Machine Learning in Bioinformatics of Protein Sequences guides readers around the rapidly advancing world of cutting-edge machine learning applications in the protein bioinformatics field. Edited by bioinformatics expert, Dr Lukasz Kurgan, and with contributions by a dozen of accomplished researchers, this book provides a holistic view of the structural bioinformatics by covering a broad spectrum of algorithms, databases and software resources for the efficient and accurate prediction and characterization of functional and structural aspects of proteins. It spotlights key advances which include deep neural networks, natural language processing-based sequence embedding and covers a wide range of predictions which comprise of tertiary structure, secondary structure, residue contacts, intrinsic disorder, protein, peptide and nucleic acids-binding sites, hotspots, post-translational modification sites, and protein function. This volume is loaded with practical information that identifies and describes leading predictive tools, useful databases, webservers, and modern software platforms for the development of novel predictive tools.
Algorithms For Computational Biology
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Author : Adrian-Horia Dediu
language : en
Publisher: Springer
Release Date : 2015-07-27
Algorithms For Computational Biology written by Adrian-Horia Dediu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-27 with Computers categories.
This book constitutes the proceedings of the Second International Conference on Algorithms for Computational Biology, AICoB 2015, held in Mexico City, Mexico, in August 2015. The 11 papers presented in this volume were carefully reviewed and selected from 23 submissions. They were organized in topical sections named: genetic processing; molecular recognition/prediction; and phylogenetics.
Genomics Data Analysis For Crop Improvement
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Author : Priyanka Anjoy
language : en
Publisher: Springer Nature
Release Date : 2024-01-09
Genomics Data Analysis For Crop Improvement written by Priyanka Anjoy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-09 with Technology & Engineering categories.
This book addresses complex problems associated with crop improvement programs, using a wide range of programming solutions, for genomics data handling and sustainable agriculture. It describes important concepts in genomics data analysis and sequence-based mapping approaches along with references. The book contains 16 chapters on recent developments in several methods of genomic data analysis for crop improvements and sustainable agriculture, all authored by eminent researchers who are experts in their fields. These chapters focus on applications of a wide range of key bioinformatics topics, including assembly, annotation, and visualization of next-generation sequencing (NGS) data; expression profiles of coding and noncoding RNA; statistical and quantitative genetics; trait-based association analysis, quantitative trait loci (QTL) mapping, and artificial intelligence in genomic studies. Real examples and case studies in the book will come in handy when applying the techniques. The relative scarcity of reference materials covering bioinformatics applications as compared with the readily available books also enhances the utility of this book. The targeted readers of the book are scientists, researchers, and bioinformaticians from genomics and advanced breeding in different areas. The book will appeal to the applied researchers engaged in crop improvements and sustainable agriculture by using bioinformatics tools, students, research project leaders, and practitioners from the various marginal disciplines and interdisciplinary research.
New Algorithms For Macromolecular Simulation
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Author : Benedict Leimkuhler
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-22
New Algorithms For Macromolecular Simulation written by Benedict Leimkuhler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-22 with Computers categories.
Molecular simulation is a widely used tool in biology, chemistry, physics and engineering. This book contains a collection of articles by leading researchers who are developing new methods for molecular modelling and simulation. Topics addressed here include: multiscale formulations for biomolecular modelling, such as quantum-classical methods and advanced solvation techniques; protein folding methods and schemes for sampling complex landscapes; membrane simulations; free energy calculation; and techniques for improving ergodicity. The book is meant to be useful for practitioners in the simulation community and for those new to molecular simulation who require a broad introduction to the state of the art.