Machine Learning For Biological Sequence Analysis

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Machine Learning For Biological Sequence Analysis

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Author : Quan Zou
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-09

Machine Learning For Biological Sequence Analysis written by Quan Zou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-09 with Science categories.

Bioinformatics Second Edition

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Author : Pierre Baldi
language : en
Publisher: MIT Press
Release Date : 2001-07-20

Bioinformatics Second Edition written by Pierre Baldi and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-20 with Computers categories.

A guide to machine learning approaches and their application to the analysis of biological data. An unprecedented wealth of data is being generated by genome sequencing projects and other experimental efforts to determine the structure and function of biological molecules. The demands and opportunities for interpreting these data are expanding rapidly. Bioinformatics is the development and application of computer methods for management, analysis, interpretation, and prediction, as well as for the design of experiments. Machine learning approaches (e.g., neural networks, hidden Markov models, and belief networks) are ideally suited for areas where there is a lot of data but little theory, which is the situation in molecular biology. The goal in machine learning is to extract useful information from a body of data by building good probabilistic models—and to automate the process as much as possible. In this book Pierre Baldi and Søren Brunak present the key machine learning approaches and apply them to the computational problems encountered in the analysis of biological data. The book is aimed both at biologists and biochemists who need to understand new data-driven algorithms and at those with a primary background in physics, mathematics, statistics, or computer science who need to know more about applications in molecular biology. This new second edition contains expanded coverage of probabilistic graphical models and of the applications of neural networks, as well as a new chapter on microarrays and gene expression. The entire text has been extensively revised.

Statistical Modelling And Machine Learning Principles For Bioinformatics Techniques Tools And Applications

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Author : K. G. Srinivasa
language : en
Publisher: Springer Nature
Release Date : 2020-01-30

Statistical Modelling And Machine Learning Principles For Bioinformatics Techniques Tools And Applications written by K. G. Srinivasa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-30 with Technology & Engineering categories.

This book discusses topics related to bioinformatics, statistics, and machine learning, presenting the latest research in various areas of bioinformatics. It also highlights the role of computing and machine learning in knowledge extraction from biological data, and how this knowledge can be applied in fields such as drug design, health supplements, gene therapy, proteomics and agriculture.

Practical Bioinformatics For Beginners From Raw Sequence Analysis To Machine Learning Applications

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Author : Lloyd Wai Yee Low
language : en
Publisher: World Scientific
Release Date : 2023-01-17

Practical Bioinformatics For Beginners From Raw Sequence Analysis To Machine Learning Applications written by Lloyd Wai Yee Low and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-17 with Science categories.

Next-Generation Sequencing (NGS) is increasingly common and has applications in various fields such as clinical diagnosis, animal and plant breeding, and conservation of species. This incredible tool has become cost-effective. However, it generates a deluge of sequence data that requires efficient analysis. The highly sought-after skills in computational and statistical analyses include machine learning and, are essential for successful research within a wide range of specializations, such as identifying causes of cancer, vaccine design, new antibiotics, drug development, personalized medicine, and increased crop yields in agriculture.This invaluable book provides step-by-step guides to complex topics that make it easy for readers to perform specific analyses, from raw sequenced data to answer important biological questions using machine learning methods. It is an excellent hands-on material for lecturers who conduct courses in bioinformatics and as reference material for professionals. The chapters are standalone recipes making them suitable for readers who wish to self-learn selected topics. Readers gain the essential skills necessary to work on sequenced data from NGS platforms; hence, making themselves more attractive to employers who need skilled bioinformaticians.

Introduction To Machine Learning And Bioinformatics

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Author : Sushmita Mitra
language : en
Publisher: CRC Press
Release Date : 2008-06-05

Introduction To Machine Learning And Bioinformatics written by Sushmita Mitra and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-05 with Mathematics categories.

Lucidly Integrates Current Activities Focusing on both fundamentals and recent advances, Introduction to Machine Learning and Bioinformatics presents an informative and accessible account of the ways in which these two increasingly intertwined areas relate to each other. Examines Connections between Machine Learning & Bioinformatics The book begins with a brief historical overview of the technological developments in biology. It then describes the main problems in bioinformatics and the fundamental concepts and algorithms of machine learning. After forming this foundation, the authors explore how machine learning techniques apply to bioinformatics problems, such as electron density map interpretation, biclustering, DNA sequence analysis, and tumor classification. They also include exercises at the end of some chapters and offer supplementary materials on their website. Explores How Machine Learning Techniques Can Help Solve Bioinformatics Problems Shedding light on aspects of both machine learning and bioinformatics, this text shows how the innovative tools and techniques of machine learning help extract knowledge from the deluge of information produced by today’s biological experiments.

Analysis Of Biological Data

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Author : Sanghamitra Bandyopadhyay
language : en
Publisher: World Scientific
Release Date : 2007

Analysis Of Biological Data written by Sanghamitra Bandyopadhyay and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Computers categories.

Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers. This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter. Sample Chapter(s). Chapter 1: Bioinformatics: Mining the Massive Data from High Throughput Genomics Experiments (160 KB). Contents: Overview: Bioinformatics: Mining the Massive Data from High Throughput Genomics Experiments (H Tang & S Kim); An Introduction to Soft Computing (A Konar & S Das); Biological Sequence and Structure Analysis: Reconstructing Phylogenies with Memetic Algorithms and Branch-and-Bound (J E Gallardo et al.); Classification of RNA Sequences with Support Vector Machines (J T L Wang & X Wu); Beyond String Algorithms: Protein Sequence Analysis Using Wavelet Transforms (A Krishnan & K-B Li); Filtering Protein Surface Motifs Using Negative Instances of Active Sites Candidates (N L Shrestha & T Ohkawa); Distill: A Machine Learning Approach to Ab Initio Protein Structure Prediction (G Pollastri et al.); In Silico Design of Ligands Using Properties of Target Active Sites (S Bandyopadhyay et al.); Gene Expression and Microarray Data Analysis: Inferring Regulations in a Genomic Network from Gene Expression Profiles (N Noman & H Iba); A Reliable Classification of Gene Clusters for Cancer Samples Using a Hybrid Multi-Objective Evolutionary Procedure (K Deb et al.); Feature Selection for Cancer Classification Using Ant Colony Optimization and Support Vector Machines (A Gupta et al.); Sophisticated Methods for Cancer Classification Using Microarray Data (S-B Cho & H-S Park); Multiobjective Evolutionary Approach to Fuzzy Clustering of Microarray Data (A Mukhopadhyay et al.). Readership: Graduate students and researchers in computer science, bioinformatics, computational and molecular biology, artificial intelligence, data mining, machine learning, electrical engineering, system science; researchers in pharmaceutical industries.

Machine Learning Based Sequence Analysis Bioinformatics And Nanopore Transduction Detection

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Author : Stephen Winters-Hilt
language : en
Publisher: Lulu.com
Release Date : 2011-05-01

Machine Learning Based Sequence Analysis Bioinformatics And Nanopore Transduction Detection written by Stephen Winters-Hilt and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-01 with Science categories.

This is intended to be a simple and accessible book on machine learning methods and their application in computational genomics and nanopore transduction detection. This book has arisen from eight years of teaching one-semester courses on various machine-learning, cheminformatics, and bioinformatics topics. The book begins with a description of ad hoc signal acquisition methods and how to orient on signal processing problems with the standard tools from information theory and signal analysis. A general stochastic sequential analysis (SSA) signal processing architecture is then described that implements Hidden Markov Model (HMM) methods. Methods are then shown for classification and clustering using generalized Support Vector Machines, for use with the SSA Protocol, or independent of that approach. Optimization metaheuristics are used for tuning over algorithmic parameters throughout. Hardware implementations and short code examples of the various methods are also described.

Applications Of Machine Learning And Deep Learning On Biological Data

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Author : Faheem Masoodi
language : en
Publisher: CRC Press
Release Date : 2023-03-13

Applications Of Machine Learning And Deep Learning On Biological Data written by Faheem Masoodi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-13 with Computers categories.

Unique selling point: Advanced AI solutions for problems in genetics, virology, and related areas of life science Core audience: Researchers in bioinformatics Place in the market: High-level reference book on advanced applied technology

Biological Sequence Analysis Using The Seqan C Library

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Author : Andreas Gogol-Döring
language : en
Publisher: CRC Press
Release Date : 2009-11-11

Biological Sequence Analysis Using The Seqan C Library written by Andreas Gogol-Döring and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Science categories.

An Easy-to-Use Research Tool for Algorithm Testing and Development Before the SeqAn project, there was clearly a lack of available implementations in sequence analysis, even for standard tasks. Implementations of needed algorithmic components were either unavailable or hard to access in third-party monolithic software products. Addressing these concerns, the developers of SeqAn created a comprehensive, easy-to-use, open source C++ library of efficient algorithms and data structures for the analysis of biological sequences. Written by the founders of this project, Biological Sequence Analysis Using the SeqAn C++ Library covers the SeqAn library, its documentation, and the supporting infrastructure. The first part of the book describes the general library design. It introduces biological sequence analysis problems, discusses the benefit of using software libraries, summarizes the design principles and goals of SeqAn, details the main programming techniques used in SeqAn, and demonstrates the application of these techniques in various examples. Focusing on the components provided by SeqAn, the second part explores basic functionality, sequence data structures, alignments, pattern and motif searching, string indices, and graphs. The last part illustrates applications of SeqAn to genome alignment, consensus sequence in assembly projects, suffix array construction, and more. This handy book describes a user-friendly library of efficient data types and algorithms for sequence analysis in computational biology. SeqAn enables not only the implementation of new algorithms, but also the sound analysis and comparison of existing algorithms. Visit SeqAn for more information.

Genome Scale Algorithm Design

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Author : Veli Mäkinen
language : en
Publisher: Cambridge University Press
Release Date : 2015-05-07

Genome Scale Algorithm Design written by Veli Mäkinen and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-07 with Science categories.

Provides an integrated picture of the latest developments in algorithmic techniques, with numerous worked examples, algorithm visualisations and exercises.