Making Mice
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Making Mice
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Author : Karen Rader
language : en
Publisher: Princeton University Press
Release Date : 2018-06-05
Making Mice written by Karen Rader and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-05 with Science categories.
Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research. Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice. This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.
Making Sense
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Author : Juli Kendall
language : en
Publisher: Stenhouse Publishers
Release Date : 2005
Making Sense written by Juli Kendall and has been published by Stenhouse Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Education categories.
Reading is all about understanding, and many English language learners simply do not understand what they are reading. Juli Kendall and Outey Khuon believe that small group comprehension lessons have a key role to play in advancing students' comprehension of texts. Making Sense outlines fifty-two lessons that teach students how to make connections, ask questions, visualize (make mental images), infer, determine importance, and synthesize. The book's five main sections are geared to the stages o
The Mouse In Biomedical Research
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Author :
language : en
Publisher: Elsevier
Release Date : 2006-12-15
The Mouse In Biomedical Research written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-15 with Science categories.
Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.
Instrumentation Between Science State And Industry
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Author : B. Joerges
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Instrumentation Between Science State And Industry written by B. Joerges and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
these. In this book, we appropriate their conception of research-technology, and ex tend it to many other phenomena which are less stable and less localized in time and space than the Zeeman/Cotton situation. In the following pages, we use the concept for instances where research activities are orientated primarily toward technologies which facilitate both the production of scientific knowledge and the production of other goods. In particular, we use the tenn for instances where instruments and meth ods· traverse numerous geographic and institutional boundaries; that is, fields dis tinctly different and distant from the instruments' and methods' initial focus. We suggest that instruments such as the ultra-centrifuge, and the trajectories of the men who devise such artefacts, diverge in an interesting way from other fonns of artefacts and careers in science, metrology and engineering with which students of science and technology are more familiar. The instrument systems developed by re search-technologists strike us as especially general, open-ended, and flexible. When tailored effectively, research-technology instruments potentially fit into many niches and serve a host of unrelated applications. Their multi-functional character distin guishes them from many other devices which are designed to address specific, nar rowly defined problems in a circumscribed arena in and outside of science. Research technology activities link universities, industry, public and private research or me trology establishments, instrument-making finns, consulting companies, the military, and metrological agencies. Research-technology practitioners do not follow the career path of the traditional academic or engineering professional.
Can T Remember What I Forgot
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Author : Sue Halpern
language : en
Publisher: Crown
Release Date : 2008-05-06
Can T Remember What I Forgot written by Sue Halpern and has been published by Crown this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-06 with Psychology categories.
An essential behind-the-scenes foray into the world of cutting-edge memory research that unveils findings about memory loss only now available to general readers. When Sue Halpern decided to emulate the first modern scientist of memory, Hermann Ebbinghaus, who experimented on himself, she had no idea that after a day of radioactive testing, her brain would become so “hot” that leaving through the front door of the lab would trigger the alarm. This was not the first time while researching Can’t Remember What I Forgot, part of which appeared in The New Yorker, that Halpern had her head examined, nor would it be the last. Halpern spent years in the company of the neuroscientists, pharmacologists, psychologists, nutritionists, and inventors who are hunting for the genes and molecules, the drugs and foods, the machines, the prosthetics, the behaviors and therapies that will stave off Alzheimer’s and other forms of dementia and keep our minds–and memories–intact. Like many of us who have had a relative or friend succumb to memory loss, who are getting older, who are hearing statistics about our own chances of falling victim to dementia, who worry that each lapse of memory portends disease, Halpern wanted to find out what the experts really knew, what the bench scientists were working on, how close science is to a cure, to treatment, to accurate early diagnosis, and, of course, whether the crossword puzzles, sudokus, and ballroom dancing we’ve been told to take up can really keep us lucid or if they’re just something to do before the inevitable overtakes us. Beautifully written, sharply observed, and deeply informed, Can’t Remember What I Forgot is a book full of vital information–and a solid dose of hope.
Genetics Of The Mouse
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Author : Jean Louis Guénet
language : en
Publisher: Springer
Release Date : 2014-11-29
Genetics Of The Mouse written by Jean Louis Guénet and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-29 with Science categories.
This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits. The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided. In short, this book offers an essential resource for all scientists who use or plan to use mice in their research.
Quilter S 1 000 Blocks
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Author : Carolyn Beam
language : en
Publisher: Penguin Group
Release Date : 2024-11-19
Quilter S 1 000 Blocks written by Carolyn Beam and has been published by Penguin Group this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-19 with Crafts & Hobbies categories.
Hundreds of quilt blocks from today's top designers! From innovative to traditional, whimsical to sophisticated, classic to unique, Quilter's 1,000 Blocks is filled with ideas for your next project! This comprehensive guide covers every block-making approach including applique, foundation-pieced, mixed techniques and pieced. It also features settings and yardages for turning your blocks into beautiful quilts, and quilt-making techniques for easy reference. This extensive block collection is sure to be a quilter's best friend!
Mouse World
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Author : Beatrix Zimmerman
language : en
Publisher: Publifye AS
Release Date : 2024-10-15
Mouse World written by Beatrix Zimmerman and has been published by Publifye AS this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-15 with Science categories.
""Mouse World"" delves into the fascinating realm of mice, exploring their biology, behavior, and global impact. This comprehensive guide illuminates the complex lives of these small mammals, from their evolutionary history to their crucial role in scientific research. The book argues that mice are far more than pests or lab subjects; they are intricate organisms vital to both ecosystems and human progress. The narrative unfolds across three main areas: 1. Mouse biology and behavior 2. Their use in scientific research 3. Their global distribution and ecological impact Readers are guided through mouse anatomy and physiology before exploring their significance in fields like genetics and neuroscience. The book then examines mouse populations worldwide, highlighting their environmental influence. Throughout, ""Mouse World"" balances scientific rigor with accessible language, employing engaging anecdotes and illustrations to elucidate complex concepts. What sets this book apart is its holistic approach, integrating knowledge from both laboratory and wild mouse studies. By drawing connections between mouse research and fields such as ecology and human psychology, it offers a unique perspective on the broader implications of mouse biology. Whether you're a student, researcher, or simply curious about nature, ""Mouse World"" provides valuable insights into these tiny but significant creatures that have shaped our understanding of life on Earth.
Happy Ending Children S Stories And More Poems Tongue Twisters Proverbs And Brain Teasers
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Author : Sr. Sabina Stella Santana
language : en
Publisher: Lulu.com
Release Date : 2008-07-01
Happy Ending Children S Stories And More Poems Tongue Twisters Proverbs And Brain Teasers written by Sr. Sabina Stella Santana and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-01 with Juvenile Nonfiction categories.
A book of children's stories, poems, tongue-twisters, proverbs, and brain-teasers from Africa by Sr. Stella Sabina, an author from Uganda who studied in Kenya and now lives and works in Indiana, USA.
What Determines Social Behavior Investigating The Role Of Emotions Self Centered Motives And Social Norms
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Author : Corrado Corradi-Dell'Acqua
language : en
Publisher: Frontiers Media SA
Release Date : 2016-09-28
What Determines Social Behavior Investigating The Role Of Emotions Self Centered Motives And Social Norms written by Corrado Corradi-Dell'Acqua and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-28 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Human behavior and decision making is subject to social and motivational influences such as emotions, norms and self/other regarding preferences. The identification of the neural and psychological mechanisms underlying these factors is a central issue in psychology, behavioral economics and social neuroscience, with important clinical, social, and even political implications. However, despite a continuously growing interest from the scientific community, the processes underlying these factors, as well as their ontogenetic and phylogenetic development, have so far remained elusive. In this Research Topic we collect articles that provide challenging insights and stimulate a fruitful controversy on the question of “what determines social behavior”. Indeed, over the last decades, research has shown that introducing a social context to otherwise abstract tasks has diverse effects on social behavior. On the one hand, it may induce individuals to act irrationally, for instance to refuse money, but on the other hand it improves individuals’ reasoning, in that formerly difficult abstract problems can be easily solved. These lines of research led to distinct (although not necessarily mutually exclusive) models for socially-driven behavioral changes. For instance, a popular theoretical framework interprets human behavior as a result of a conflict between cognition and emotion, with the cognitive system promoting self-interested choices, and the emotional system (triggered by the social context) operating against them. Other theories favor social norms and deontic heuristics in biasing human reasoning and encouraging choices that are sometimes in conflict with one’s interest. Few studies attempted to disentangle between these (as well as other) models. As a consequence, although insightful results arise from specific domains/tasks, a comprehensive theoretical framework is still missing. Furthermore, studies employing neuroimaging techniques have begun to shed some light on the neural substrates involved in social behavior, implicating consistently (although not exclusively) portions of the limbic system, the insular and the prefrontal cortex. In this context, a challenge for present research lies not only in further mapping the brain structures implicated in social behavior, or in describing in detail the functional interaction between these structures, but in showing how the implicated networks relate to different theoretical models. This is Research Topic hosted by members of the Swiss National Center of Competence in Research “Affective Sciences – Emotions in Individual Behaviour and Social Processes”. We collected contributions from the international community which extended the current knowledge about the psychological and neural structures underlying social behavior and decision making. In particular, we encouraged submissions from investigators arising from different domains (psychology, behavioral economics, affective sciences, etc.) implementing different techniques (behavior, electrophysiology, neuroimaging, brain stimulations) on different populations (neurotypical adults, children, brain damaged or psychiatric patients, etc.). Animal studies are also included, as the data reported are of high comparative value. Finally, we also welcomed submissions of meta-analytical articles, mini-reviews and perspective papers which offer provocative and insightful interpretations of the recent literature in the field.