Malaria Parasites


Malaria Parasites
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Malaria Parasites


Malaria Parasites
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Author : Andrew P. Waters
language : en
Publisher: Caister Academic Press Limited
Release Date : 2004

Malaria Parasites written by Andrew P. Waters and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.


The completion of the Plasmodium falciparum genome sequence in late 2002 heralded a new era in malaria research. The search began in earnest for new drugs and vaccines to combat malaria, a disease which afflicts up to 500 million people worldwide and is responsible for the deaths of more than one million people each year. The new genomic data is aiding a greater understanding of the living parasite and its interaction with the insect vector and human host. In this book internationally renowned experts provide up-to-date reviews of the most important aspects of post-genomic malaria research. Topics covered include: the P. falciparum genome and model parasites, bioinformatics and genome databases, microsatellite analysis, analysis of chromosome structure, cell cycle to RNA polymerase I and II mediated gene expression, role of the nuclear genome, the parasite surface and cell biology, and much more. The book is essential to all researchers working in this highly topical field and is recommended reading for scientists in other areas of biology and medicine.



Malaria Parasites And Other Haemosporidia


Malaria Parasites And Other Haemosporidia
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Author : Percy Cyril Claude Garnham
language : en
Publisher:
Release Date : 1966

Malaria Parasites And Other Haemosporidia written by Percy Cyril Claude Garnham and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1966 with Apicomplexa categories.




Diagnosis Of Malaria


Diagnosis Of Malaria
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Author : Francisco J. López-Antuñano
language : en
Publisher:
Release Date : 1990

Diagnosis Of Malaria written by Francisco J. López-Antuñano and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.




Malaria Parasites


Malaria Parasites
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Author : Barbara Ciletti
language : en
Publisher:
Release Date : 2012

Malaria Parasites written by Barbara Ciletti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.




Malaria


Malaria
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Author : Friedrich Frischknecht
language : en
Publisher: Springer Nature
Release Date : 2023-03-15

Malaria written by Friedrich Frischknecht and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-15 with Medical categories.


Friedrich Frischknecht gives an insight into malaria and the biological complexity of the parasites that trigger it. The author takes the reader on a journey from the historical discovery of the pathogen to the modern methods of vaccine development. He explains how genetic manipulations help to understand the parasite and to develop novel vaccination approaches. He explains the difficulties that need to be overcome to eradicate malaria. The author: Prof. Dr. Friedrich Frischknecht studied biochemistry at the Freie Universität Berlin and did his PhD on smallpox viruses at the European Molecular Biology Laboratory (EMBL) in Heidelberg. After a research stay at the Institut Pasteur in Paris, he has been head of a research group at the University Hospital in Heidelberg since 2005 and is interested in the molecular basis of the movement of malaria parasites.



Malariology


Malariology
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Author : A. A. Sandosham
language : en
Publisher: NUS Press
Release Date : 1983

Malariology written by A. A. Sandosham and has been published by NUS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Social Science categories.




Breaking The Cycle Attacking The Malaria Parasite In The Liver


Breaking The Cycle Attacking The Malaria Parasite In The Liver
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Author : Ute Frevert
language : en
Publisher: Frontiers Media SA
Release Date : 2016-01-06

Breaking The Cycle Attacking The Malaria Parasite In The Liver written by Ute Frevert and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-06 with Electronic book categories.


Despite significant progress in the global fight against malaria, this parasitic infection is still responsible for nearly 300 million clinical cases and more than half a million deaths each year, predominantly in African children less than 5 years of age. The infection starts when mosquitoes transmit small numbers of parasites into the skin. From here, the parasites travel with the bloodstream to the liver where they undergo an initial round of replication and maturation to the next developmental stage that infects red blood cells. A vaccine capable of blocking the clinically silent liver phase of the Plasmodium life cycle would prevent the subsequent symptomatic phase of this tropical disease, including its frequently fatal manifestations such as severe anemia, acute lung injury, and cerebral malaria. Parasitologists, immunologists, and vaccinologists have come to appreciate the complexity of the adaptive immune response against the liver stages of this deadly parasite. Lymphocytes play a central role in the elimination of Plasmodium infected hepatocytes, both in humans and animal models, but our understanding of the exact cellular interactions and molecular effector mechanisms that lead to parasite killing within the complex hepatic microenvironment of an immune host is still rudimentary. Nevertheless, recent collaborative efforts have led to promising vaccine approaches based on liver stages that have conferred sterile immunity in humans – the University of Oxford's Ad prime / MVA boost vaccine, the Naval Medical Research Center’s DNA prime / Ad boost vaccine, Sanaria Inc.'s radiation-attenuated whole sporozoite vaccine, and Radboud University Medical Centre’s and Sanaria's derived chemoprophylaxis with sporozoites vaccines. The aim of this Research Topic is to bring together researchers with expertise in malariology, immunology, hepatology, antigen discovery and vaccine development to provide a better understanding of the basic biology of Plasmodium in the liver and the host’s innate and adaptive immune responses. Understanding the conditions required to generate complete protection in a vaccinated individual will bring us closer to our ultimate goal, namely to develop a safe, scalable, and affordable malaria vaccine capable of inducing sustained high-level protective immunity in the large proportion of the world’s population constantly at risk of malaria.



Malaria Methods And Protocols


Malaria Methods And Protocols
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Author : Denise L. Doolan
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Malaria Methods And Protocols written by Denise L. Doolan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.


The Plasmodium spp. parasite was identified as the causative agent of malaria in 1880, and the mosquito was identified as the vector in 1897. Despite subsequent efforts focused on the epidemiology, cell biology, immunology, molecular biology, and clinical manifestations of malaria and the Plasmodium parasite, there is still no licensed vaccine for the prevention of malaria. Physical barriers (bed nets, window screens) and chemical prevention methods (insecticides and mosquito repellents) intended to interfere with the transmission of the disease are not highly effective, and the profile of resistance of the parasite to chemoprophylactic and chemotherapeutic agents is increasing. The dawn of the new millennium has seen a resurgence of interest in the disease by government and philanthropic organizations, but we are still faced with compl- ities of the parasite, the host, and the vector, and the interactions among them. Malaria Methods and Protocols offers a comprehensive collection of protocols describing conventional and state-of-the-art techniques for the study of malaria, as well as associated theory and potential problems, written by experts in the field. The major themes reflected here include assessing the risk of infection and severity of disease, laboratory models, diagnosis and typing, molecular biology techniques, immunological techniques, cell biology techniques, and field applications.



Two Monographs On Malaria And The Parasites Of Malarial Fevers


Two Monographs On Malaria And The Parasites Of Malarial Fevers
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Author : Ettore Marchiafava
language : en
Publisher:
Release Date : 1894

Two Monographs On Malaria And The Parasites Of Malarial Fevers written by Ettore Marchiafava and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1894 with Blood categories.




Rodent Malaria


Rodent Malaria
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Author : R. Killick-Kendrick
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Rodent Malaria written by R. Killick-Kendrick and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.


Rodent Malaria reviews significant findings concerning malaria parasites of rodents, including their taxonomy, zoogeography, and evolution, along with life cycles and morphology; genetics and biochemistry; and concomitant infections. This volume is organized into eight chapters and begins by sketching out the history of the discovery of rodent as well as aspects of parasitology, immunology, and chemotherapy. These concepts are investigated two decades following Ignace Vincke's major discovery and Meir Yoeli's successful establishment of the method of cyclical transmission of the parasite. The following chapters focus on the taxonomy and systematics of the subgenus Vinckeia, with reference to the concepts of species and subspecies of animals and the degree to which they apply to malaria parasites, in particular to those of rodents. The discussion then shifts to how the rodent malaria parasites provide a unique insight into the subcellular organization of Plasmodium species, the use of rodent malaria as an experimental model to study immunological responses, and infectious agents that interact with malaria parasites. The book concludes with a chapter on malaria chemotherapy, with emphasis on the value of rodent malaria in antimalarial drug screening and the use of antimalarial drugs as biological probes. This book will be of interest to protozoologists and physicians as well as those from other disciplines including biochemistry, immunology, pharmacology, cell biology, and genetics.