Management Of Peritoneal Metastases Cytoreductive Surgery Hipec And Beyond


Management Of Peritoneal Metastases Cytoreductive Surgery Hipec And Beyond
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Management Of Peritoneal Metastases Cytoreductive Surgery Hipec And Beyond


Management Of Peritoneal Metastases Cytoreductive Surgery Hipec And Beyond
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Author : Aditi Bhatt
language : en
Publisher: Springer
Release Date : 2018-04-02

Management Of Peritoneal Metastases Cytoreductive Surgery Hipec And Beyond written by Aditi Bhatt and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-02 with Medical categories.


The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject. This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.



Management Of Peritoneal Surface Malignancies Cytoreductive Surgery Hipec Pipac And Beyond


Management Of Peritoneal Surface Malignancies Cytoreductive Surgery Hipec Pipac And Beyond
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Author : Amine Souadka
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-05

Management Of Peritoneal Surface Malignancies Cytoreductive Surgery Hipec Pipac And Beyond written by Amine Souadka and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-05 with Medical categories.


Peritoneal surface malignancies (PSM) include a heterogeneous group of primary tumors, like peritoneal mesothelioma, and peritoneal metastases from various origins such as ovarian, gastric, colorectal, or appendicular cancers. Their pathophysiology is complex and still not fully elucidated. Historically, due to their dismal prognosis, peritoneal surface malignancies were considered a terminal condition and treated as such in palliative intent.. Surgery has become pivotal in the treatment of PSM and the development of specific techniques of cytoreductive surgery (peritonectomies, “en-bloc” resection) open up a new era of curative intent treatments.



Cancer Regional Therapy


Cancer Regional Therapy
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Author : Yuman Fong
language : en
Publisher: Springer Nature
Release Date : 2019-12-10

Cancer Regional Therapy written by Yuman Fong and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-10 with Medical categories.


This book is a state-of-the-art overview of cancer regional therapy (CRT) for the surgeons and interventional radiologists active in CRT development and research. The goals of this book are 1) to review the theory and practice of cancer regional therapies including pharmacology, devices, techniques, and workflow, 2) illustrate the most common procedures performed in the interventional and operating rooms, and 3) discuss data supporting use of CRT. This is meant to be a definitive text on the theory and practice of CRT. It begins with a summary of the history, technical principles that underlie regional therapy. The following parts discuss current data and practice in peritoneal, liver, limb, pleural and other sites. Included in the practice are considerations of workflow and financial issues revolving around CRT. Novel techniques and therapies under investigation are presented to inform the direction of the field. Cancer Regional Therapy summarizes the history, current technology, common procedures, and future prospects in this field and includes procedures from many surgical and interventional radiologic disciplines.



Peritoneal Surface Malignancies


Peritoneal Surface Malignancies
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Author : Emel Canbay
language : en
Publisher: Springer
Release Date : 2015-07-09

Peritoneal Surface Malignancies written by Emel Canbay and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-09 with Medical categories.


This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies as a new emerging specialty. Combined treatment of cytoreductive surgery (CRS) and hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) introduced by our leader Paul H. Sugarbaker are performed to treat peritoneal metastases by surgeons all around the world. Therefore this book is focused on detailed surgical anatomy of the peritoneum, preoperative clinical assessment of the peritoneal surface malignancy, patient preparation and operation room equipments, different surgical procedures for CRS and reconstruction, intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) and neoadjuvant intraperitoneal chemotherapy, early postoperative intraperitoneal chemotherapy (EPIC) and molecular basis of peritoneal surface malignancies. The chapter on molecular mechanisms of the formation of peritoneal carcinomatosis provides insight into a rapidly expanding knowledge within this speciality. This book should be valuable for surgical oncologists who deal with multimodal treatment for peritoneal surface malignancies, as well as for the trained peritonectomy surgeons. For the senior surgeons, it will also introduce new techniques and approaches in this field such as dealing with the omental cakes and massive organ involvement that requires multi-organ resection.



Peritoneal Tumors And Metastases


Peritoneal Tumors And Metastases
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Author : Beate Rau
language : en
Publisher: Springer Nature
Release Date : 2021-05-13

Peritoneal Tumors And Metastases written by Beate Rau and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-13 with Medical categories.


This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC. Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.



Treatment Of Peritoneal Surface Malignancies An Issue Of Surgical Oncology Clinics E Book


Treatment Of Peritoneal Surface Malignancies An Issue Of Surgical Oncology Clinics E Book
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Author : Jesus Esquivel
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-10-30

Treatment Of Peritoneal Surface Malignancies An Issue Of Surgical Oncology Clinics E Book written by Jesus Esquivel and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-30 with Medical categories.


This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. Jesus Esquivel, will focus on the current status and future directions of the treatment of the most common peritoneal surface malignancies: appendix cancer, colorectal cancer, ovarian cancer, gastric cancer, and peritoneal mesothelioma. This issue will also outline some of the most common issues that arise regarding cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC), such as pharmacokinetic rationale of heat and intraperitoneal chemotherapy, HIPEC techniques and safety considerations, how to start a peritoneal surface malignancy program, anesthesia considerations during cytoreductive surgery and HIPEC, patient selection for cytoreductive surgery and HIPEC, and the role of dystemic chemotherapy in the management of peritoneal surface malignancies of appendiceal and colorectal origin.



Peritoneal Carcinomatosis Principles Of Management


Peritoneal Carcinomatosis Principles Of Management
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Author : Paul H. Sugarbaker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Peritoneal Carcinomatosis Principles Of Management written by Paul H. Sugarbaker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.



Perioperative Chemotherapy


Perioperative Chemotherapy
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Author : U. Metzger
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Perioperative Chemotherapy written by U. Metzger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.



Peritoneal Carcinomatosis A Multidisciplinary Approach


Peritoneal Carcinomatosis A Multidisciplinary Approach
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Author : wim ceelen
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-06

Peritoneal Carcinomatosis A Multidisciplinary Approach written by wim ceelen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Medical categories.


This is the first volume to provide a multidisciplinary approach to peritoneal carcinomatosis encompassing molecular mechanisms, histopathology, regional and systemic cytotoxic therapy, and surgical options. Illustrations aid the reader throughout in the many facets of this disease. The book will be of particular interest for medical, surgical and gynecological oncologists faced with the complexities of decision making in patients suffering from PC.



Treatment Of Peritoneal Surface Malignancies An Issue Of Surgical Oncology Clinics


Treatment Of Peritoneal Surface Malignancies An Issue Of Surgical Oncology Clinics
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Author : Jesus Esquivel
language : en
Publisher: Saunders
Release Date : 2012-10-05

Treatment Of Peritoneal Surface Malignancies An Issue Of Surgical Oncology Clinics written by Jesus Esquivel and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-05 with Medical categories.


This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. Jesus Esquivel, will focus on the current status and future directions of the treatment of the most common peritoneal surface malignancies: appendix cancer, colorectal cancer, ovarian cancer, gastric cancer, and peritoneal mesothelioma. This issue will also outline some of the most common issues that arise regarding cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC), such as pharmacokinetic rationale of heat and intraperitoneal chemotherapy, HIPEC techniques and safety considerations, how to start a peritoneal surface malignancy program, anesthesia considerations during cytoreductive surgery and HIPEC, patient selection for cytoreductive surgery and HIPEC, and the role of dystemic chemotherapy in the management of peritoneal surface malignancies of appendiceal and colorectal origin.