Mass Spectrometry For The Clinical Laboratory
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Mass Spectrometry For The Clinical Laboratory
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Author : Hari Nair
language : en
Publisher: Academic Press
Release Date : 2016-11-02
Mass Spectrometry For The Clinical Laboratory written by Hari Nair and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-02 with Medical categories.
Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab
Mass Spectrometry In The Clinical Laboratory General Principles And Guidance Approved Guideline
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Author : Donald H. Chace
language : en
Publisher:
Release Date : 2007
Mass Spectrometry In The Clinical Laboratory General Principles And Guidance Approved Guideline written by Donald H. Chace and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Diagnosis, Laboratory categories.
Mass Spectrometry An Issue Of Clinics In Laboratory Medicine E Book
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Author : Nigel Clarke
language : en
Publisher: Elsevier Health Sciences
Release Date : 2011-10-03
Mass Spectrometry An Issue Of Clinics In Laboratory Medicine E Book written by Nigel Clarke and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-03 with Medical categories.
This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.
Mass Spectrometry In Life Sciences And Clinical Laboratory
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Author : Goran Mitulović
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-06-02
Mass Spectrometry In Life Sciences And Clinical Laboratory written by Goran Mitulović and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-02 with Science categories.
Mass spectrometry is a state-of-the-art tool for basic biological research and applied clinical diagnostics. This book covers sample preparation for mass spectrometric analysis for proteomics, clinical studies, and food analysis. In addition, it explores possible directions for further developing the technology and its potential applications.
Principles And Applications Of Clinical Mass Spectrometry
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Author : Nader Rifai
language : en
Publisher: Elsevier
Release Date : 2018-06-26
Principles And Applications Of Clinical Mass Spectrometry written by Nader Rifai and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-26 with Science categories.
Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field
Clinical Applications Of Mass Spectrometry In Biomolecular Analysis
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Author : Uttam Garg
language : en
Publisher: Springer Nature
Release Date : 2022-09-20
Clinical Applications Of Mass Spectrometry In Biomolecular Analysis written by Uttam Garg and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-20 with Science categories.
This updated volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and limited need for specialized reagents. These techniques are essential in laboratory fields including endocrinology, biochemical genetics, drug analysis, proteomics, and pathogen identification. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols, Second Edition is an ideal resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.
A Practical Guide To Implementing Clinical Mass Spectrometry Systems
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Author : Neil Leaver
language : en
Publisher: ILM Publications
Release Date : 2011
A Practical Guide To Implementing Clinical Mass Spectrometry Systems written by Neil Leaver and has been published by ILM Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
Mass spectrometry is becoming increasingly popular in the field of therapeutic drug monitoring. The aim of this publication is to provide practical guidance for laboratories on the implementation of mass spectrometry into a clinical service where there might be limited expertise in the technique. This guidance is the author's personal recommendation based on over ten years' experience of clinical mass spectrometry. Throughout the text, examples are given to illustrate issues that a clinical laboratory might encounter. While some examples relate to the field of immunosuppressive drug monitoring, the issues are common and relevant to any clinical application. The guidance provided is also applicable to instrumentation made by any manufacturer. This practical guide covers instrument selection through business planning to installation, risk management and validation, and includes suggestions for future prospects for this developing field.
Clinical Applications Of Mass Spectrometry
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Author : Uttam Garg
language : en
Publisher: Humana
Release Date : 2016-08-23
Clinical Applications Of Mass Spectrometry written by Uttam Garg and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Science categories.
As mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step procedures for the analysis of number of analytes of clinical importance. This versatile and expansive volume covers mass spectrometry methods for analytes including a variety of drugs, hormones, and metabolic compounds spanning the disciplines of toxicology, therapeutic drug monitoring, endocrinology, and pediatric metabolism. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to the analytes, lists of the necessary materials and reagents, readily reproducible analytical protocols, and detailed notes on troubleshooting and avoiding known pitfalls. Comprehensive and dependable, Clinical Applications of Mass Spectrometry: Methods and Protocols offers its readers a wide array of valuable methods for experienced mass spectrometric labs that are looking to introduce new analyses as well as for those laboratories currently considering the addition of this resourceful and vital technology.
Clinical Applications Of Mass Spectrometry In Biomolecular Analysis
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Author : Uttam Garg
language : en
Publisher: Humana
Release Date : 2015-11-25
Clinical Applications Of Mass Spectrometry In Biomolecular Analysis written by Uttam Garg and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-25 with Medical categories.
This volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and no need for specialized reagents. The techniques described are a must for the measurement of many clinically relevant analytes in the fields of drug analysis, endocrinology, and inborn errors of metabolism. Each chapter provides a brief introduction about a specified analyte, followed by detailed instructions on the analytical protocol. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols is a great resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.
Clinical Mass Spectrometry An Issue Of Clinics In Laboratory Medicine
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Author : Nigel Clarke
language : en
Publisher: Saunders
Release Date : 2011
Clinical Mass Spectrometry An Issue Of Clinics In Laboratory Medicine written by Nigel Clarke and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.