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Mathematical And Computational Modelling Across The Scales


Mathematical And Computational Modelling Across The Scales
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Mathematical And Computational Modelling Across The Scales


Mathematical And Computational Modelling Across The Scales
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Author : Pedro Diez
language : en
Publisher: Springer Nature
Release Date : 2025-06-25

Mathematical And Computational Modelling Across The Scales written by Pedro Diez and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with Computers categories.


Many physical and engineering systems deal with micro-, meso-, macro-, and multi-scale phenomena. The accurate description and the reliable simulation of such phenomena entail major challenges from the point of view of both mathematical modelling and computational engineering. This book covers a selection of challenges related to "Mathematical and Computational Modelling Across the Scales”, stemming from the lecture notes of the XX edition of the Jacques-Louis Lions Spanish-French School in Numerical Simulations in Physics & Engineering. The thematic focus is broad, encompassing mathematical models of complex physical problems, theoretical results on their derivation, and development of numerical methods for their efficient simulation. The contributions of the book include: uncertainty quantification for phenomena at different scales such as epidemic dynamics, medical imaging, and geophysical exploration; structural health monitoring integrating small-scale sensor data in large-scale computational models; frontier numerical methods for the simulation of geophysical and heliophysical dynamics accounting for multi-scale, heterogeneous media; multi-physics, multi-scale models for the mechanobiology of atheroma plaques formation; locomotion models for swimming at the micro-scale; mathematical foundations of quantum mechanics phenomena at the micro-scale. The book is addressed to scientists and engineers, from both academia and industry, interested in the mathematical modelling and numerical simulation of a variety of complex systems in physics and engineering characterised by multiple scales.



Computational Mathematical Modeling


Computational Mathematical Modeling
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Author : Daniela Calvetti
language : en
Publisher: SIAM
Release Date : 2013-03-21

Computational Mathematical Modeling written by Daniela Calvetti and has been published by SIAM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-21 with Mathematics categories.


Interesting real-world mathematical modelling problems are complex and can usually be studied at different scales. The scale at which the investigation is carried out is one of the factors that determines the type of mathematics most appropriate to describe the problem. The book concentrates on two modelling paradigms: the macroscopic, in which phenomena are described in terms of time evolution via ordinary differential equations; and the microscopic, which requires knowledge of random events and probability. The exposition is based on this unorthodox combination of deterministic and probabilistic methodologies, and emphasizes the development of computational skills to construct predictive models. To elucidate the concepts, a wealth of examples, self-study problems, and portions of MATLAB code used by the authors are included. This book, which has been extensively tested by the authors for classroom use, is intended for students in mathematics and the physical sciences at the advanced undergraduate level and above.



Mathematical And Computational Modelling Across The Scales


Mathematical And Computational Modelling Across The Scales
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Author : Pedro Diez
language : en
Publisher:
Release Date : 2025-04-30

Mathematical And Computational Modelling Across The Scales written by Pedro Diez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-30 with Computers categories.


Many physical and engineering systems deal with micro-, meso-, macro-, and multi-scale phenomena. The accurate description and the reliable simulation of such phenomena entail major challenges from the point of view of both mathematical modelling and computational engineering. This book covers a selection of challenges related to "Mathematical and Computational Modelling Across the Scales", stemming from the lecture notes of the XX edition of the Jacques-Louis Lions Spanish-French School in Numerical Simulations in Physics & Engineering. The thematic focus is broad, encompassing mathematical models of complex physical problems, theoretical results on their derivation, and development of numerical methods for their efficient simulation. The contributions of the book include: uncertainty quantification for phenomena at different scales such as epidemic dynamics, medical imaging, and geophysical exploration; structural health monitoring integrating small-scale sensor data in large-scale computational models; frontier numerical methods for the simulation of geophysical and heliophysical dynamics accounting for multi-scale, heterogeneous media; multi-physics, multi-scale models for the mechanobiology of atheroma plaques formation; locomotion models for swimming at the micro-scale; mathematical foundations of quantum mechanics phenomena at the micro-scale. The book is addressed to scientists and engineers, from both academia and industry, interested in the mathematical modelling and numerical simulation of a variety of complex systems in physics and engineering characterised by multiple scales.



Nonlocal Modeling Analysis And Computation


Nonlocal Modeling Analysis And Computation
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Author : Qiang Du
language : en
Publisher: SIAM
Release Date : 2019-03-20

Nonlocal Modeling Analysis And Computation written by Qiang Du and has been published by SIAM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-20 with Science categories.


Studies of complexity, singularity, and anomaly using nonlocal continuum models are steadily gaining popularity. This monograph provides an introduction to basic analytical, computational, and modeling issues and to some of the latest developments in these areas. Nonlocal Modeling, Analysis, and Computation includes motivational examples of nonlocal models, basic building blocks of nonlocal vector calculus, elements of theory for well-posedness and nonlocal spaces, connections to and coupling with local models, convergence and compatibility of numerical approximations, and various applications, such as nonlocal dynamics of anomalous diffusion and nonlocal peridynamic models of elasticity and fracture mechanics. A particular focus is on nonlocal systems with a finite range of interaction to illustrate their connection to local partial differential equations and fractional PDEs. These models are designed to represent nonlocal interactions explicitly and to remain valid for complex systems involving possible singular solutions and they have the potential to be alternatives for as well as bridges to existing models. The author discusses ongoing studies of nonlocal models to encourage the discovery of new mathematical theory for nonlocal continuum models and offer new perspectives on traditional models, analytical techniques, and algorithms.



An Introduction To Mathematical Modeling


An Introduction To Mathematical Modeling
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Author : Edward A. Bender
language : en
Publisher: Courier Corporation
Release Date : 2012-05-23

An Introduction To Mathematical Modeling written by Edward A. Bender and has been published by Courier Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-23 with Mathematics categories.


Employing a practical, "learn by doing" approach, this first-rate text fosters the development of the skills beyond the pure mathematics needed to set up and manipulate mathematical models. The author draws on a diversity of fields — including science, engineering, and operations research — to provide over 100 reality-based examples. Students learn from the examples by applying mathematical methods to formulate, analyze, and criticize models. Extensive documentation, consisting of over 150 references, supplements the models, encouraging further research on models of particular interest. The lively and accessible text requires only minimal scientific background. Designed for senior college or beginning graduate-level students, it assumes only elementary calculus and basic probability theory for the first part, and ordinary differential equations and continuous probability for the second section. All problems require students to study and create models, encouraging their active participation rather than a mechanical approach. Beyond the classroom, this volume will prove interesting and rewarding to anyone concerned with the development of mathematical models or the application of modeling to problem solving in a wide array of applications.



Targeted Therapies


Targeted Therapies
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Author : Daniel Gioeli
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-02

Targeted Therapies written by Daniel Gioeli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-02 with Medical categories.


This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included. Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.



Multiscale Modeling In Biomechanics And Mechanobiology


Multiscale Modeling In Biomechanics And Mechanobiology
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Author : Suvranu De
language : en
Publisher: Springer
Release Date : 2014-10-10

Multiscale Modeling In Biomechanics And Mechanobiology written by Suvranu De and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Technology & Engineering categories.


Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.



Mathematical Modeling And Simulation


Mathematical Modeling And Simulation
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Author : Kai Velten
language : en
Publisher: John Wiley & Sons
Release Date : 2009-06-01

Mathematical Modeling And Simulation written by Kai Velten and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-01 with Science categories.


This concise and clear introduction to the topic requires only basic knowledge of calculus and linear algebra - all other concepts and ideas are developed in the course of the book. Lucidly written so as to appeal to undergraduates and practitioners alike, it enables readers to set up simple mathematical models on their own and to interpret their results and those of others critically. To achieve this, many examples have been chosen from various fields, such as biology, ecology, economics, medicine, agricultural, chemical, electrical, mechanical and process engineering, which are subsequently discussed in detail. Based on the author`s modeling and simulation experience in science and engineering and as a consultant, the book answers such basic questions as: What is a mathematical model? What types of models do exist? Which model is appropriate for a particular problem? What are simulation, parameter estimation, and validation? The book relies exclusively upon open-source software which is available to everybody free of charge. The entire book software - including 3D CFD and structural mechanics simulation software - can be used based on a free CAELinux-Live-DVD that is available in the Internet (works on most machines and operating systems).



Differential Dynamical Systems Revised Edition


Differential Dynamical Systems Revised Edition
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Author : James D. Meiss
language : en
Publisher: SIAM
Release Date : 2017-01-24

Differential Dynamical Systems Revised Edition written by James D. Meiss and has been published by SIAM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-24 with Mathematics categories.


Differential equations are the basis for models of any physical systems that exhibit smooth change. This book combines much of the material found in a traditional course on ordinary differential equations with an introduction to the more modern theory of dynamical systems. Applications of this theory to physics, biology, chemistry, and engineering are shown through examples in such areas as population modeling, fluid dynamics, electronics, and mechanics. Differential Dynamical Systems begins with coverage of linear systems, including matrix algebra; the focus then shifts to foundational material on nonlinear differential equations, making heavy use of the contraction-mapping theorem. Subsequent chapters deal specifically with dynamical systems concepts?flow, stability, invariant manifolds, the phase plane, bifurcation, chaos, and Hamiltonian dynamics. This new edition contains several important updates and revisions throughout the book. Throughout the book, the author includes exercises to help students develop an analytical and geometrical understanding of dynamics. Many of the exercises and examples are based on applications and some involve computation; an appendix offers simple codes written in Maple, Mathematica, and MATLAB software to give students practice with computation applied to dynamical systems problems.