Mathematical Principles In Bioinformatics
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Mathematical Principles In Bioinformatics
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Author : Stephen S.-T. Yau
language : en
Publisher: Springer Nature
Release Date : 2024-01-11
Mathematical Principles In Bioinformatics written by Stephen S.-T. Yau and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-11 with Computers categories.
This textbook introduces bioinformatics to students in mathematics with no biology background assumed and it provides solid mathematical tools for biology students along with an understanding of how to implement them in bioinformatics problems. In addition to the basics, the text offers new approaches to understanding biological sequences. The concise presentation distinguishes itself from others on the subject, discussing and providing principles that relate to current open problems in bioinformatics as well as considering a variety of models. The convex hull principle is highlighted, opening a new interdisciplinary research area at the intersection of biology, mathematics, and computer science. Prerequisites include first courses in linear algebra, probability and statistics, and mathematical analysis. Researchers in mathematics, biology, and math-biology, will also find aspects of this text useful. This textbook is written based on the authors' research works that have been published in various journals along with the lecture notes used when teaching bioinformatics courses at the University of Illinois at Chicago and at Tsinghua University. The content may be divided into two parts. The first part includes three chapters, introducing some basic concepts. Chapter 1 provides biological background in molecular biology for mathematicians. Chapter 2 describes biological databases that are commonly used. Chapter 3 is concerned with alignment methods including global/local alignment, heuristic alignment, and multiple alignment. The second part consisting of five chapters, describes several bioinformatics principles using a rigorous mathematical formulation. Chapter 4 introduces the time-frequency spectral principle and its applications in bioinformatics. In Chapters 5 and 6, two strategies are used, the graphical representation and the natural vector method, to represent biological sequences, and conduct sequence comparison and phylogenetic analysis without alignment. Chapter 7 presents the convex hull principle and shows how it can be used to mathematically determine whether a certain amino acid sequence can be a protein. The last chapter summarizes additional mathematical ideas relating to sequence comparisons, such as new feature vectors and metrics. This part focuses on the governing principle in biology and provides plenty of alignment-free methods, which cannot be found in any other book.
The Hitchhiker S Guide To Genesis
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Author : Quick Savant
language : en
Publisher: Scott Campbell
Release Date : 2024-11-29
The Hitchhiker S Guide To Genesis written by Quick Savant and has been published by Scott Campbell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-29 with Science categories.
"DNA: The Alien Code"...The Origin of Life and the Shocking Truth About Our Genetic Past Evolutionary theory by Charles Darwin changed our knowledge of life in the mid-19th century. One question remained: Where did life begin? We know a lot about the creation of our universe but how life began remains a mystery. We investigate Nobel winner Francis Crick's novel idea of DNA structure in this intriguing inquiry. Crick's controversial argument that DNA, the cornerstone of life, may have originated off-planet changes our view of life on Earth. Crick believed that an intelligent alien society engineered and spread DNA through panspermia. Could extraterrestrials have engineered ourselves and all life on Earth? Do we derive from alien "hybrids," designed to carry a vanished civilization's genes? This book explores Crick's bold proposal by reviewing convincing scientific evidence for directed panspermia, the idea that life was deliberately carried across space to nurture intelligence on numerous planets, including Earth. From research with extremophiles—microbes that can survive space—to frightening UFO sightings and official declarations of alien contacts, the evidence is increasing. Microbes may have “hitchhiked” on comets, asteroids, meteors, planetary pieces, or cosmic dust. DNA patterns that suggest an artificial origin support Crick's bold prediction. DNA may be an intergalactic artifact that could reveal our cosmic destiny, according to mathematicians, astrophysicists, and Crick. But the narrative continues. New findings about the Last Universal Common Ancestor (LUCA) and alien life’s involvement in intelligent species evolution pose intriguing questions about our destiny. Close reading of Genesis' original passages reveals alien influence in human development. Ready to meet our creators—or their descendants? Could humans and aliens merge? Join the search for life's origins as we digest the idea that our DNA may hold the solution to the universe's biggest riddles.
Math And Bio 2010
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Author : Lynn Arthur Steen
language : en
Publisher: MAA
Release Date : 2005
Math And Bio 2010 written by Lynn Arthur Steen and has been published by MAA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Mathematics categories.
"Math and bio 2010 grew out of 'Meeting the Challenges: Education across the Biological, Mathematical and Computer Sciences,' a joint project of the Mathematical Association of America (MAA), the National Science Foundation Division of Undergraduate Education (NSF DUE), the National Institute of General Medical Sciences (NIGMS), the American Association for the Advancement of Science (AAAS), and the American Society for Microbiology (ASM)."--Foreword, p. vi
Bioinformatics And Functional Genomics
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Author : Jonathan Pevsner
language : en
Publisher: John Wiley & Sons
Release Date : 2005-03-04
Bioinformatics And Functional Genomics written by Jonathan Pevsner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-04 with Science categories.
Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.
Key Concepts In Discrete Mathematics
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Author : Udayan Bhattacharya
language : en
Publisher: Educohack Press
Release Date : 2025-02-20
Key Concepts In Discrete Mathematics written by Udayan Bhattacharya and has been published by Educohack Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-20 with Science categories.
"Key Concepts in Discrete Mathematics" offers a comprehensive introduction to the fascinating realm of discrete mathematics, covering a diverse array of topics essential for students and professionals in computer science, mathematics, engineering, and related fields. Through clear explanations, illustrative examples, and engaging exercises, we provide readers with a solid foundation in discrete mathematics and its practical applications. Our book covers a wide range of topics, from fundamental concepts like sets, relations, and functions to advanced topics such as graph theory, combinatorics, and algorithm analysis. We present complex concepts in a clear and accessible manner, with detailed explanations and step-by-step examples guiding readers through each topic. We emphasize practical applications and real-world examples that demonstrate the relevance of discrete mathematics in various fields, including computer science, cryptography, network theory, and optimization. Abundant exercises and problems, ranging from basic to challenging, allow readers to practice and reinforce their understanding of key concepts and techniques. Additional online resources, including solutions to selected exercises, interactive quizzes, and supplementary materials, enhance the learning experience and provide opportunities for further exploration. Whether used as a textbook in a classroom setting or as a self-study guide, "Key Concepts in Discrete Mathematics" serves as an invaluable resource for students seeking to deepen their understanding and for educators and professionals interested in exploring this essential area of mathematics.
Structural And Functional Aspects Of Biocomputing Systems For Data Processing
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Author : Vignesh, U.
language : en
Publisher: IGI Global
Release Date : 2023-01-20
Structural And Functional Aspects Of Biocomputing Systems For Data Processing written by Vignesh, U. and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-20 with Computers categories.
Due to the diversity of contexts in which biological computation is performed, a major problem is the selection of functional-oriented techniques for the analysis of biological sequences in a huge environment. The performances of various sequences in biocomputational algorithms are evaluated with variant features to prove their efficiency in real-time environments. Structural and Functional Aspects of Biocomputing Systems for Data Processing provides insight into the structural and functional aspects of biological sequences and the pattern recognition they embed into the data processingcepts, methodologies, and empirical research advances of various biological data mining systems through machine learning approaches. Covering topics such as DNA sequencing, high-speed architecture, and medical image processing, this premier reference source is an essential resource for healthcare professionals, biological systems in biocomputing systems. It extends recent con specialists, industrial professionals, PCR testing professionals, scientists, bioinformaticians, students and educators of higher education, librarians, researchers, and academicians.
Bioinformatics
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Author : Prakash S. Lohar
language : en
Publisher: MJP Publisher
Release Date : 2019-06-12
Bioinformatics written by Prakash S. Lohar and has been published by MJP Publisher this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-12 with Computers categories.
Introduction Evolution of Computers Biological Macromolecules Basic Techniques in Bioinformatics Biological Databases Sequence Alignment Multiple Sequence Alignments Computational Gene Prediction Proteomics Genomics Latest Information Covers Basics of Computers Includes Programming Languages Emphasis on Techniques Elaborative Style Many Web Resources and URLs Review Questions Glossary References Index.
Information Processing And Living Systems
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Author : Vladimir B Bajic
language : en
Publisher: World Scientific
Release Date : 2005-06-01
Information Processing And Living Systems written by Vladimir B Bajic and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-01 with Science categories.
Information processing and information flow occur in the course of an organism's development and throughout its lifespan. Organisms do not exist in isolation, but interact with each other constantly within a complex ecosystem. The relationships between organisms, such as those between prey or predator, host and parasite, and between mating partners, are complex and multidimensional. In all cases, there is constant communication and information flow at many levels.This book focuses on information processing by life forms and the use of information technology in understanding them. Readers are first given a comprehensive overview of biocomputing before navigating the complex terrain of natural processing of biological information using physiological and analogous computing models. The remainder of the book deals with “artificial” processing of biological information as a human endeavor in order to derive new knowledge and gain insight into life forms and their functioning. Specific innovative applications and tools for biological discovery are provided as the link and complement to biocomputing.Since “artificial” processing of biological information is complementary to natural processing, a better understanding of the former helps us improve the latter. Consequently, readers are exposed to both domains and, when dealing with biological problems of their interest, will be better equipped to grasp relevant ideas.
Mathematical Grammar Of Biology
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Author : Michel Eduardo Beleza Yamagishi
language : en
Publisher: Springer
Release Date : 2017-08-31
Mathematical Grammar Of Biology written by Michel Eduardo Beleza Yamagishi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-31 with Mathematics categories.
This seminal, multidisciplinary book shows how mathematics can be used to study the first principles of DNA. Most importantly, it enriches the so-called “Chargaff’s grammar of biology” by providing the conceptual theoretical framework necessary to generalize Chargaff’s rules. Starting with a simple example of DNA mathematical modeling where human nucleotide frequencies are associated to the Fibonacci sequence and the Golden Ratio through an optimization problem, its breakthrough is showing that the reverse, complement and reverse-complement operators defined over oligonucleotides induce a natural set partition of DNA words of fixed-size. These equivalence classes, when organized into a matrix form, reveal hidden patterns within the DNA sequence of every living organism. Intended for undergraduate and graduate students both in mathematics and in life sciences, it is also a valuable resource for researchers interested in studying invariant genomic properties.
Bioinformatics
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Author : Andrzej Polanski
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-04-19
Bioinformatics written by Andrzej Polanski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-19 with Computers categories.
This textbook presents mathematical models in bioinformatics and describes biological problems that inspire the computer science tools used to manage the enormous data sets involved. The first part of the book covers mathematical and computational methods, with practical applications presented in the second part. The mathematical presentation avoids unnecessary formalism, while remaining clear and precise. The book closes with a thorough bibliography, reaching from classic research results to very recent findings. This volume is suited for a senior undergraduate or graduate course on bioinformatics, with a strong focus on mathematical and computer science background.