Mechanisms In Science
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Evaluating Evidence Of Mechanisms In Medicine
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Author : Veli-Pekka Parkkinen
language : en
Publisher: Springer
Release Date : 2018-07-13
Evaluating Evidence Of Mechanisms In Medicine written by Veli-Pekka Parkkinen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-13 with Medical categories.
This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.
What Biological Functions Are And Why They Matter
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Author : Justin Garson
language : en
Publisher: Cambridge University Press
Release Date : 2019-01-10
What Biological Functions Are And Why They Matter written by Justin Garson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-10 with History categories.
This accessible book presents a new theory of biological functions and connects it to contemporary problems in philosophy and science.
In Search Of Mechanisms
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Author : Carl F. Craver
language : en
Publisher: University of Chicago Press
Release Date : 2013-10-07
In Search Of Mechanisms written by Carl F. Craver and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-07 with Science categories.
Neuroscientists investigate the mechanisms of spatial memory. Molecular biologists study the mechanisms of protein synthesis and the myriad mechanisms of gene regulation. Ecologists study nutrient cycling mechanisms and their devastating imbalances in estuaries such as the Chesapeake Bay. In fact, much of biology and its history involves biologists constructing, evaluating, and revising their understanding of mechanisms. With In Search of Mechanisms, Carl F. Craver and Lindley Darden offer both a descriptive and an instructional account of how biologists discover mechanisms. Drawing on examples from across the life sciences and through the centuries, Craver and Darden compile an impressive toolbox of strategies that biologists have used and will use again to reveal the mechanisms that produce, underlie, or maintain the phenomena characteristic of living things. They discuss the questions that figure in the search for mechanisms, characterizing the experimental, observational, and conceptual considerations used to answer them, all the while providing examples from the history of biology to highlight the kinds of evidence and reasoning strategies employed to assess mechanisms. At a deeper level, Craver and Darden pose a systematic view of what biology is, of how biology makes progress, of how biological discoveries are and might be made, and of why knowledge of biological mechanisms is important for the future of the human species.
The Routledge Handbook Of Mechanisms And Mechanical Philosophy
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Author : Stuart Glennan
language : en
Publisher: Taylor & Francis
Release Date : 2017-07-06
The Routledge Handbook Of Mechanisms And Mechanical Philosophy written by Stuart Glennan and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with Philosophy categories.
Scientists studying the burning of stars, the evolution of species, DNA, the brain, the economy, and social change, all frequently describe their work as searching for mechanisms. Despite this fact, for much of the twentieth century philosophical discussions of the nature of mechanisms remained outside philosophy of science. The Routledge Handbook of Mechanisms and Mechanical Philosophy is an outstanding reference source to the key topics, problems, and debates in this exciting subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors, the Handbook is divided into four Parts: Historical perspectives on mechanisms The nature of mechanisms Mechanisms and the philosophy of science Disciplinary perspectives on mechanisms. Within these Parts central topics and problems are examined, including the rise of mechanical philosophy in the seventeenth century; what mechanisms are made of and how they are organized; mechanisms and laws and regularities; how mechanisms are discovered and explained; dynamical systems theory; and disciplinary perspectives from physics, chemistry, biology, biomedicine, ecology, neuroscience, and the social sciences. Essential reading for students and researchers in philosophy of science, the Handbook will also be of interest to those in related fields, such as metaphysics, philosophy of psychology, and history of science.
Mechanisms And Consciousness
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Author : Marek Pokropski
language : en
Publisher: Routledge
Release Date : 2021-11-29
Mechanisms And Consciousness written by Marek Pokropski and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-29 with Philosophy categories.
This book develops a new approach to naturalizing phenomenology. The author proposes to integrate phenomenology with the mechanistic framework that offers new methodological perspectives for studying complex mental phenomena such as consciousness. While mechanistic explanatory models are widely applied in cognitive science, their approach to describing subjective phenomena is limited. The author argues that phenomenology can fill this gap. He proposes two novel ways of integrating phenomenology and mechanism. First, he presents a new reading of phenomenological analyses as functional analyses. Such functional phenomenology delivers a functional sketch of a target system and provides constraints on the space of possible mechanisms. Second, he develops the neurophenomenological approach in the direction of dynamic modeling of experience. He shows that neurophenomenology can deliver dynamical constraints on mechanistic models and thus inform the search for an underlying mechanism. Mechanisms and Consciousness will be of interest to scholars and advanced students working in phenomenology, philosophy of mind, and the cognitive sciences.
Europe S New Scientific Elite
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Author : Barbara Hoenig
language : en
Publisher: Routledge
Release Date : 2017-04-21
Europe S New Scientific Elite written by Barbara Hoenig and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-21 with Social Science categories.
Winner of the Harald Kaufmann Prize for Senior Researchers, 2018 This book examines the question of whether the process of European integration in research funding has led to new forms of oligarchization and elite formation in the European Research Area. Based on a study of the European Research Council (ERC), the author investigates profound structural change in the social organization of science, as the ERC intervenes in public science systems that, until now, have largely been organized at the national level. Against the background of an emerging new science policy, Europe’s New Scientific Elite explores the social mechanisms that generate, reproduce and modify existing dynamics of stratification and oligarchization in science, shedding light on the strong normative impact of the ERC’s funding on problem-choice in science, the cultural legitimacy and future vision of science, and the building of new research councils of national, European and global scope. A comparative, theory-driven investigation of European research funding, this book will appeal to social scientists with interests in the sociology of knowledge.
Mechanisms Of Morphogenesis
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Author : Jamie A. Davies
language : en
Publisher: Academic Press
Release Date : 2013-02-18
Mechanisms Of Morphogenesis written by Jamie A. Davies and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-18 with Science categories.
Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form, Mechanisms of Morphogenesis, second edition is a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. By combining hard data with computer modeling, Mechanisms of Morphogenesis, second edition equips readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic program is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future - Includes over 200 four-color figures - Offers an integrated view of theoretical developmental biology and computer modelling with laboratory-based discoveries - Covers experimental techniques as a guide to the reader - Organized around principles and mechanisms, using them to integrate discoveries from a range of organisms and systems
Discovering Cell Mechanisms
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Author : William Bechtel
language : en
Publisher: Cambridge University Press
Release Date : 2006
Discovering Cell Mechanisms written by William Bechtel and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Philosophy categories.
Between 1940 and 1970 pioneers in the new field of cell biology discovered the operative parts of cells and their contributions to cell life. They offered mechanistic accounts that explained cellular phenomena by identifying the relevant parts of cells, the biochemical operations they performed, and the way in which these parts and operations were organised to accomplish important functions. Cell biology was a revolutionary science but in this book it also provides fuel for yet another revolution, one that focuses on the very conception of science itself. Laws have traditionally been regarded as the primary vehicle of explanation, but in the emerging philosophy of science it is mechanisms that do the explanatory work. Bechtel emphasises how mechanisms were discovered, focusing especially on the way in which new instruments made these inquiries possible. He also describes how new journals and societies provided institutional structure to this new enterprise.
The New Mechanical Philosophy
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Author : Stuart Glennan
language : en
Publisher: Oxford University Press
Release Date : 2017
The New Mechanical Philosophy written by Stuart Glennan and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Philosophy categories.
This volume argues for a new image of science that understands both natural and social phenomena to be the product of mechanisms, casting the work of science as an effort to understand those mechanisms. Glennan offers an account of the nature of mechanisms and of the models used to represent them in physical, life, and social sciences.
Mechanisms In Ancient Chinese Books With Illustrations
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Author : Kuo-Hung Hsiao
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-12
Mechanisms In Ancient Chinese Books With Illustrations written by Kuo-Hung Hsiao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-12 with Technology & Engineering categories.
This book presents a unique approach for studying mechanisms and machines with drawings that were depicted unclearly in ancient Chinese books. The historical, cultural and technical backgrounds of the mechanisms are explained, and various mechanisms described and illustrated in ancient books are introduced. By utilizing the idea for the conceptual design of modern mechanisms, all feasible designs of ancient mechanisms with uncertain members and joints that meet the technical standards of the subjects’ time periods are synthesized systematically. Ancient Chinese crossbows (the original crossbow and repeating crossbows), textile mechanisms (silk-reeling mechanism, spinning mechanisms, and looms), and many other artisan's tool mechanisms are used as illustrated examples. Such an approach provides a logical method for the reconstruction designs of ancient mechanisms with uncertain structures. It also provides an innovative direction for researchers to further identify the original structures of mechanisms and machines with drawings in ancient literature. This book can be used as a textbook and/or supplemental reading material for courses related to history of ancient (Chinese) machinery and creative mechanism design for senior and graduate students.