Mechanisms And Novel Therapies In Graves Orbitopathy Current Update

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Mechanisms And Novel Therapies In Graves Orbitopathy Current Update
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Author : Kelvin Kam-Lung Chong
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-24
Mechanisms And Novel Therapies In Graves Orbitopathy Current Update written by Kelvin Kam-Lung Chong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-24 with Medical categories.
Graves Orbitopathy
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Author : W.M. Wiersinga
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2017-08-21
Graves Orbitopathy written by W.M. Wiersinga and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-21 with Medical categories.
Ten years ago, the first edition of Graves’ Orbitopathy: A Multidisciplinary Approach was published. Since then, the book has become very popular and much has happened in the field to warrant a third edition. What has not changed is the successful and attractive question-and-answer format of the book. In the 3rd, revised and expanded edition, new chapters have been added on co-morbidity, local treatment modalities, novel immunosuppressive therapy, detailed protocols, and questions frequently asked by patients. All chapters of the previous edition have been thoroughly updated. Subjects covered then include the pathology of Graves’ Orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures; and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Additionally, ample consideration is given to the new 2016 ETA/EUGOGO guidelines on the management of GO.
Graves Orbitopathy
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Author : Wilmar M. Wiersinga
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2010-01-01
Graves Orbitopathy written by Wilmar M. Wiersinga and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-01 with Medical categories.
The significant progress in the understanding of the pathogenesis and the treatment of Graves' orbitopathy (GO) has warranted a second edition of this book within three years of the first. Now also fully incorporated is the EUGOGO consensus statement on management of GO, which since has been accepted worldwide as a useful guideline. Furthermore all chapters have been thoroughly updated. Subjects covered include the pathology of GO and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Two new chapters have been added: one describing the socioeconomic impact of the disease and the other outlining the Amsterdam Declaration on Graves' Orbitopathy. The successful question-and-answer format facilitates its use as a reference guide for medical practitioners and surgeons working in the fields of ophthalmology, internal medicine, endocrinology, pediatrics, immunology, as well as otorhinolaryngology.
Emergencies Of The Orbit And Adnexa
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Author : Bipasha Mukherjee
language : en
Publisher: Springer
Release Date : 2016-12-15
Emergencies Of The Orbit And Adnexa written by Bipasha Mukherjee and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-15 with Medical categories.
This handbook on orbital, lacrimal and eyelid emergencies deals with such situations in a practical manner guiding the ophthalmologists in accurate handling and making them more proficient and confident in managing vision and life-threatening emergencies. With 51 chapters and more than 350 images, this book covers all the eye emergencies that generalist and specialist ophthalmologists can expect to come across in their day to day practices. It can be argued that the orbit can no more be called ‘Pandora’s Box’ because of the unpredictable nature of its contents. This perception has changed over the years due to the advent of improved diagnostic, in particular, imaging techniques. However, since medical residency provides very little exposure to orbital and adnexal disorders, most clinicians are inexperienced and unsure about their management. Facing an emergency situation where improper management can rapidly worsen the condition leading to blindness or even death of the patient is every ophthalmologist’s nightmare. The emergent nature of these conditions does not always provide for a leeway to refer these patients to an orbit and oculoplasty specialist, who are few and far between. By the time the patient reaches his destination, his vision maybe irrevocably lost. The legal implications of such mismanagement can be significant too. This book is a quick and essential resource to manage and refer eye emergencies with confidence.
A Year In Review Discussions In Autoimmune And Autoinflammatory Disorders
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Author : Raphaela Goldbach-Mansky
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-31
A Year In Review Discussions In Autoimmune And Autoinflammatory Disorders written by Raphaela Goldbach-Mansky and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-31 with Medical categories.
Novel Treatment Strategies For Thyroid Autoimmunity And Thyroid Cancer
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Author : Artur Bossowski,
language : en
Publisher: Frontiers Media SA
Release Date : 2024-09-20
Novel Treatment Strategies For Thyroid Autoimmunity And Thyroid Cancer written by Artur Bossowski, and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-20 with Medical categories.
Thyroid autoimmunity is a common condition in which the immune system mistakenly attacks the thyroid gland, leading to inflammation and damage to the gland. This can result in a range of thyroid pathologies, including hypothyroidism and hyperthyroidism. The prevalence of thyroid autoimmunity is increasing worldwide, and it is more common in women than in men. Recent advances in research on thyroid autoimmunity and pathology have improved our understanding of the mechanisms underlying the development of autoimmune thyroid disease and have identified new targets for therapeutic interventions. These advances have also led to improvements in treatment strategies for patients with thyroid autoimmunity. This Research Topic welcomes contributions of any type (clinical trial, correction, editorial, general commentary, hypothesis & theory, methods, mini review, opinion, original research, perspective, policy and practice reviews, review, study protocol, systematic review, technology and code) on topics around recent studies on new treatment strategies for patients with thyroid autoimmunity, thyroid orbitopathy and selected thyroid cancer.
Thyroid Autoimmunity
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Author : A. Pinchera
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Thyroid Autoimmunity written by A. Pinchera and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.
Graves Disease
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Author : Rebecca S. Bahn
language : en
Publisher: Springer
Release Date : 2015-03-31
Graves Disease written by Rebecca S. Bahn and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-31 with Medical categories.
This indispensable volume is designed to facilitate the best possible physician–patient discussion on Graves’ disease by providing the most up-to-date evidence-based information in a clinically useful and patient-centric manner. Comprehensive and covering such topics as Professionalism and the Art of Patient-centric Thyroidology, the Immunopathogenesis of Graves’ Disease, and the Diagnosis and Management of Thyroid Storm, the book addresses all the important refinements in the treatment of Graves’ disease in recent years. These include new indications and contraindications for antithyroid drugs, improved approaches to radioactive iodine therapy, the development of novel surgical techniques, and a better understanding of the combined use of these modalities, among other developments. Also addressed are the advances in the treatment of GO, including the use of disease activity and severity assessments to inform management decisions and the completion of the first randomized controlled therapeutic trials. Developed by a renowned group of internationally respected authorities, Graves’ Disease: A Comprehensive Guide for Clinicians is a significant new reference that will be of great interest to all clinicians who treat this debilitating condition.
Peyman S Principles Practice Of Ophthalmology
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Author : N Venkatesh Prajna
language : en
Publisher: Jaypee Brothers Medical Publishers
Release Date : 2019-04-30
Peyman S Principles Practice Of Ophthalmology written by N Venkatesh Prajna and has been published by Jaypee Brothers Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-30 with Medical categories.
This two-volume set is a complete guide to the diagnosis and management of ophthalmic diseases and disorders. Volume One begins with an overview of basic sciences, ocular pathology, and clinical examination. The remainder of this volume and Volume Two discuss numerous diseases that may occur in different parts of the eye. The second edition has been fully revised and features many new topics including innovative techniques in cataract surgery, imaging modalities, pharmacotherapy, new surgical procedures, and much more. This comprehensive text is highly illustrated with nearly 1900 clinical photographs, radiological images, diagrams, tables and boxes. Key points Two-volume guide to diagnosis and management of ophthalmic disorders and diseases Fully revised, second edition with many new topics Highly illustrated with nearly 1900 photographs, diagrams and tables Previous edition (Vol 1 9780721672113 and Vol 2 9780721672120) published in 1980
Recent Advances In Understanding The Genetics Of Immunological Disorders
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Author : Che Kang Lim
language : en
Publisher: Frontiers Media SA
Release Date : 2024-12-13
Recent Advances In Understanding The Genetics Of Immunological Disorders written by Che Kang Lim and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-13 with Science categories.
Immunological disorders are diseases or conditions due to the dysfunction of the immune system. They include primary immunodeficiency syndromes, autoimmune diseases, asthma, allergy, and autoinflammatory syndromes. These disorders disrupt our body’s ability to defend against pathogens. In addition, it may lead to exaggerated chronic inflammatory responses and tissue damage. Immunological disorders are clinically and genetically heterogeneous. The phenotypic spectrum of the diseases is broad in some of the disorders. On the other hand, the clinical phenotype derived from distinct genotypes can overlap, and the same phenotype can be cross-shared in different disorders. Therefore, accurate diagnosis and effective management are challenging. Over the last decade, advances in genomics and sequencing platforms have accelerated the understanding of how candidate genes contribute to the development of immunological disorders. Significant progress has been made in discovering disease-causing genes for rare monogenic immunological disorders, especially in immunodeficiency syndrome. These findings shed insights into disease mechanisms and facilitated the identification of new biomarkers that can help in diagnosis, prognosis, and development of novel clinical therapeutic approaches.