Mechanisms Linking Aging Diseases And Biological Age Estimation
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Mechanisms Linking Aging Diseases And Biological Age Estimation
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Author : Sara C. Zapico
language : en
Publisher: CRC Press
Release Date : 2017-03-27
Mechanisms Linking Aging Diseases And Biological Age Estimation written by Sara C. Zapico and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-27 with Law categories.
This book focuses on four of the hallmarks of aging: aspartic acid racemization, advanced glycation end products, telomere shortening and mitochondrial mutations; describing their role in aging and diseases; and their application to age-at-death estimation in forensic sciences in greater depth, displaying the interconnecting pathways among these processes. An additional chapter related to Epigenetics and its role in aging, diseases, and forensic age estimation is also included. This book is aimed at a broad audience: from students being introduced to aging, diseases, and forensic science research to scientists in biomedicine and forensics complementing their knowledge in their respective fields while also increasing their knowledge in other disciplines.
Psychological Support By Cognitive Behavioral Therapy For X Linked Adrenoleukodystrophy
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :
Psychological Support By Cognitive Behavioral Therapy For X Linked Adrenoleukodystrophy written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Psychology categories.
The journey of understanding and managing X-Linked Adrenoleukodystrophy (ALD) is one marked by complexity, resilience, and a profound emotional toll on individuals and families alike. As a genetic disorder that impacts both the body and the mind, ALD presents not only physical challenges but also psychological burdens that require a thoughtful, compassionate approach. This book, Psychological Support by Cognitive Behavioral Therapy for X-Linked Adrenoleukodystrophy, was born out of a deep commitment to bridge the gap between genetic understanding and mental health support, providing patients, families, and mental health professionals with practical tools to navigate the emotional landscape of living with ALD. Our approach centers on the powerful benefits of Cognitive Behavioral Therapy (CBT), a proven therapeutic framework known for its versatility in addressing both emotional and behavioral aspects of chronic conditions. Through CBT, individuals can build resilience, develop healthy coping strategies, and find meaning even in the face of genetic challenges. This book integrates foundational knowledge about genetics and ALD with detailed CBT strategies, tailored specifically to the psychological needs that arise when living with this rare disorder. This work is intended as a supportive companion for those grappling with the realities of ALD, from patients and caregivers to healthcare providers. By beginning with essential background on ALD and genetic principles, we aim to equip readers with the knowledge needed to fully appreciate the psychological aspects of this condition. Subsequent sections explore the nuances of CBT, providing step-by-step guidance, actionable tools, and case-based examples to illustrate how CBT can be adapted to support individuals at every stage of their journey. The book also includes practical pain management strategies and a range of CBT techniques aimed at helping patients manage symptoms, navigate the healthcare system, and address the social and emotional challenges unique to ALD. To those facing the challenges of ALD, we hope this book provides not only therapeutic support but also a sense of empowerment. While genetic conditions may alter the path of one’s life, they do not define it. With the right support, patients and families can build resilience, nurture hope, and pursue a meaningful life. In these pages, may you find tools, insights, and encouragement for the journey ahead.
Fundamentals Of Health Neuroscience
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Author : Yi-Yuan Tang
language : en
Publisher: Elsevier
Release Date : 2024-08-07
Fundamentals Of Health Neuroscience written by Yi-Yuan Tang and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-07 with Medical categories.
Health Neuroscience is a new interdisciplinary field encompassing research from cognitive, affective, and social neuroscience, health psychology, physical and mental health, and science of behavior change. This new field addresses the longstanding gap among neuroscience, health and behavior change within the context of health promotion. Fundamentals of Health Neuroscience explores key topics and research, including basic principles, psychological and neural processes, brain and body interaction, and gene x brain x environment interactions. This book will also cover prevention and intervention strategies for health decisions and promotion across the lifespan. Chapters will integrate the latest research findings and explore several key topics, such as: How does the brain serve both as a predictor and an outcome of health? How can people improve self-control and achieve physical and mental health? What does brain plasticity and resilience tell us about learning and development throughout our life? How is the sense of meaning in life affected by dopamine and reward systems in the brain? - Introduces a new interdisciplinary field of Health Neuroscience including its basic and translational research and applications - Reviews current research on biomarkers of brain health and aging - Discusses brain-body connection and health behavior change
Epigenetics Of Aging
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Author : Trygve O. Tollefsbol
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11
Epigenetics Of Aging written by Trygve O. Tollefsbol and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
Women In Science Translational Medicine 2021
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Author : Victoria Bunik
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-25
Women In Science Translational Medicine 2021 written by Victoria Bunik and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-25 with Medical categories.
Papers Of The Conference On Genetics Of Aging And Longevity 2012
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Author : Alexey Moskalev
language : en
Publisher: Frontiers E-books
Release Date : 2014-11-12
Papers Of The Conference On Genetics Of Aging And Longevity 2012 written by Alexey Moskalev and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-12 with Genetics categories.
Handbook Of Epigenetics
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Author : Trygve O. Tollefsbol
language : en
Publisher: Academic Press
Release Date : 2022-09-08
Handbook Of Epigenetics written by Trygve O. Tollefsbol and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-08 with Science categories.
Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related diseases, transposable elements and epigenetics, X chromosome inactivation, and the epigenetics of drug addiction, among other topics. Throughout this edition, greater emphasis falls on epigenomic analyses and incorporating multi-omics approaches rather than gene-specific analyses. In addition, this edition has also been enhanced with step-by-step instructions in research methods, as well as easy-to-digest disease case studies and clinical trials that provide context and applied examples of recent advances in disease understanding and epigenetic therapeutics. These features empower researchers to reproduce the approaches and studies discussed and aid clinical translation. Live links across chapters tie in relevant external datasets and resources. - Provides a timely and comprehensive collection of fully up-to-date coverage of epigenetics - Covers basic epigenetic biology, research methods and technology, disease relationships and clinical medicine - Written at a verbal and technical level that can be understood by scientists and students alike, with chapter summaries and conclusions included throughout - Discusses exciting new topics in epigenetics, such as DNA methylation clocks in age-related diseases, transposable elements and epigenetics, X chromosome inactivation, and the epigenetics of drug addiction - Includes step-by-step instructions in research protocols to aid reproducibility, as well as easy-to-digest disease case studies and clinical trials, providing context and applied examples of recent clinical translation
Human Aging
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Author : Calogero Caruso
language : en
Publisher: Academic Press
Release Date : 2021-05-11
Human Aging written by Calogero Caruso and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-11 with Science categories.
Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it. - Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging - Offers the ability to access cross-sectional knowledge more easily - Written by expert researchers in biogerontology who are actively involved in various fields within aging research
Evidence Based Functional Foods For Prevention Of Age Related Diseases
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Author : Surajit Pathak
language : en
Publisher: Springer Nature
Release Date : 2023-07-06
Evidence Based Functional Foods For Prevention Of Age Related Diseases written by Surajit Pathak and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-06 with Science categories.
This book illustrates the recent advancements in the role of functional foods in preventing age-related disorders. It correlates age-related diseases and the effect of dietary compounds from different functional foods, herbs, and nutraceuticals. Notably, the book describes unique nutrition problems in many chronic diseases such as bone disease, cardiovascular disorders, brain disorders, immune disorders, and cancers. The book also discusses the use of functional foods for controlling osteoporosis, improving bone strength, maintaining dental health, controlling obesity, gut health, and maintaining immune function using functional ingredients such as probiotics and prebiotics. Further, it presents the state of the art of aging and nutrigenomics research and the molecular mechanisms underlying the beneficial effects of bioactive nutrients on major aging-related disorders. Finally, the book embodies the latest findings and the mechanisms of actions of functional foods in aging and degenerative diseases and their beneficial uses in the aged population.
Handbook Of The Biology Of Aging
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Author : Edward J. Masoro
language : en
Publisher: Elsevier
Release Date : 2011-04-28
Handbook Of The Biology Of Aging written by Edward J. Masoro and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-28 with Medical categories.
The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions.