Mechanisms Of Antibiotic Resistance
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Antibiotic Resistance
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Author : Kateryna Kon
language : en
Publisher: Academic Press
Release Date : 2016-06-14
Antibiotic Resistance written by Kateryna Kon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-14 with Medical categories.
Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance. Discusses methods used to fight antibiotic-resistant infection based on a deep understanding of mechanisms involved in the development of the resistance Provides information on modern methods used to fight antibiotic resistance Covers a wide range of alternative methods to fight bacterial resistance, offering the most complete information available Discusses both newly emerging trends and traditionally applied methods to fight antibiotic resistant infections in light of recent scientific developments Offers the most up-to-date information in fighting antibiotic resistance Includes involvement of contributors all across the world, presenting questions of interest to readers of both developed and developing countries
Antimicrobial Drug Resistance
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Author : Douglas L. Mayers
language : en
Publisher: Springer
Release Date : 2017-06-19
Antimicrobial Drug Resistance written by Douglas L. Mayers and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-19 with Medical categories.
The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.
Mechanisms Of Antibiotic Resistance
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Author : Jun Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2015-06-01
Mechanisms Of Antibiotic Resistance written by Jun Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Antibiotics categories.
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Antibiotic Drug Resistance
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Author : José-Luis Capelo-Martínez
language : en
Publisher: John Wiley & Sons
Release Date : 2019-09-24
Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-24 with Medical categories.
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Mechanisms Of Antibiotic Resistance
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Author :
language : en
Publisher:
Release Date : 2015
Mechanisms Of Antibiotic Resistance written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Drug Discovery Targeting Drug Resistant Bacteria
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Author : Prashant Kesharwani
language : en
Publisher: Academic Press
Release Date : 2020-05-15
Drug Discovery Targeting Drug Resistant Bacteria written by Prashant Kesharwani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-15 with Medical categories.
Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war
Evolution Of Genetic Mechanisms Of Antibiotic Resistance
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Author : Silvia Buroni
language : en
Publisher: Frontiers Media SA
Release Date : 2019-12-05
Evolution Of Genetic Mechanisms Of Antibiotic Resistance written by Silvia Buroni and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-05 with categories.
Since the first introduction of antibiotics into clinical practice, microbial drug resistance has emerged as a major obstacle in the treatment of infections. Recently, the combination of emergence of a complex variety of multidrug resistant strains and the dearth of newly discovered molecules to effectively target and eliminate these strains, has made antibiotic resistance one of the major public health problems of this century. Although different strategies can be adopted to contain the emergence and spread of antibiotic resistance, including (i) antimicrobial stewardship, (ii) infection control, and (iii) tighter control over the use of antibiotics in agriculture and breeding, a better understanding of the dynamics that lead to the evolution of antibiotic resistance remains essential for the development of more efficient strategies to combat this phenomenon. The recent developments in genomics have greatly contributed to expand our knowledge on the mechanisms of microbial resistance, and of the processes by which they emerge, develop and spread. Different approaches and expertise can be used to accelerate advances in this area, ranging from clinical studies on the evolution of resistance in vivo, to theoretical modeling and the study of evolution in the laboratory.
Bacterial Resistance To Antibiotics
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Author : Boyan B. Bonev
language : en
Publisher: John Wiley & Sons
Release Date : 2019-06-10
Bacterial Resistance To Antibiotics written by Boyan B. Bonev and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-10 with Science categories.
AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
Bacterial Mechanisms Of Antibiotic Resistance A Structural Perspective
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Author : Vassiliy Bavro
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-26
Bacterial Mechanisms Of Antibiotic Resistance A Structural Perspective written by Vassiliy Bavro and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-26 with categories.
Antibiotic Resistance Mechanisms And Antimicrobial Approaches
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Author : Cooper Smith
language : en
Publisher: States Academic Press
Release Date : 2021-11-16
Antibiotic Resistance Mechanisms And Antimicrobial Approaches written by Cooper Smith and has been published by States Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Medical categories.
Antimicrobial resistance develops when micro-organisms evolve different mechanisms to protect themselves from the effects of antimicrobials. Such micro-organisms that develop antimicrobial resistance are difficult to treat and require higher doses or alternative medications that are more toxic to them. When micro-organisms are resistant to multiple antimicrobials, then, they are called multidrug resistant. All classes of microbes, i.e. bacteria, fungi, protozoa, viruses, can develop resistance. The bacteria that are resistant to a wide range of antibiotics are known as extensively drug resistant or superbugs. Antibiotic resistance can be spontaneous as a result of random mutations or can be caused by extensive use of anti-microbials which encourage the selection of mutants that are resistant to them. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of antibiotic resistance. It covers in detail some existent theories and innovative concepts revolving around antibiotic resistance. This book is a vital tool for all researching and studying this field.