Mechanotransduction
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Mechanotransduction
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Author : Paul A. Sundaram
language : en
Publisher: Academic Press
Release Date : 2020-11-18
Mechanotransduction written by Paul A. Sundaram and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-18 with Technology & Engineering categories.
Mechanotransduction: Cell Signaling to Cell Response covers the cell machinery responsible for the process of mechanotransduction and the manner in which cells respond to an external mechanical stimulus. The effect of mechanical stimulus on individual cells and entire tissues is discussed, with an emphasis on the practical results of this physiological process. Mechanotransduction of stem cells and cancerous cells are also covered, along with future directions in this yet nascent field. This book gives insights on basic processes that occur (or may occur) in the human body as a result of the application of mechanical stimulus. It is ideal for both biomedical engineers and biologists, and is an ideal resource for teaching. It provides a current state of conceptual and practical aspects of the field and will enable students and professionals to venture further into this incipient area which is of fundamental importance to biomedical engineering and biology fields. Covers fundamental concepts of signaling in cells as a result of mechanical stimulus Includes the physiological results of mechanical stimulus on the human body Explores the advantages of mechanical loads on the human body
Mechanotransduction
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Author :
language : en
Publisher: Academic Press
Release Date : 2014-07-29
Mechanotransduction written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-29 with Science categories.
Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. Volume 126 features in-depth reviews that focus on the tools required to investigate mechanotransduction. Additional chapters focus on how we can use these tools to answer fundamental questions about the interaction of physical forces with cell biology, morphogenesis, and function of mature structures. Chapters in the volume are authored by a unique combination of cell biologists and engineers, providing a range of perspectives on mechanotransduction. Provides a unique combination of perspectives from biologists and engineers Engaging to people of many training backgrounds
Cellular Mechanotransduction
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Author : Mohammad R. K. Mofrad
language : en
Publisher: Cambridge University Press
Release Date : 2014-07-31
Cellular Mechanotransduction written by Mohammad R. K. Mofrad and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-31 with Technology & Engineering categories.
'Mechanotransduction' is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.
Mechanosensitivity And Mechanotransduction
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Author : Irina Kiseleva
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-18
Mechanosensitivity And Mechanotransduction written by Irina Kiseleva and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-18 with Science categories.
This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail. This Volume focuses on molecular mechanisms of mechanosensitivity and mechanotransduction via cytoskeleton. Integrin-mediated mechanotransduction, the role of actin cytoskeleton and the role of other cytoskeletal elements are discussed. It contains a detailed description of several stretch-induced signaling cascades with multiple levels of crosstalk between different pathways. It contains a description of the role of nitric oxide in regulation of cardiac activity and in regulation of mechanically gated channels in the heart. In the heart mechanical signals are propagated into the intracellular space primarily via integrin-linked complexes, and are subsequently transmitted from cell to cell via paracrine signaling. Biochemical signals derived from mechanical stimuli activate both acute phosphorylation of signaling cascades, such as in the PI3K, FAK, and ILK pathways, and long-term morphological modii cations via intracellular cytoskeletal reorganization and extracellular matrix remodelling. Cellular and molecular effects of mechanical stretch on vascular cells are also discussed. This Volume highlights the role of mechanotransduction in the lung, in bone and joint tissues. For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K+ channels functioning in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Currently, investigations of the molecular mechanisms of mechanosensitivity and mechanotransduction are focused on several issues. The majority of studies investigate intracellular signaling pathways. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different organs and tissues and allows to predict changes, which arise due to alterations of their environment. Possibly such knowledge will allow the development of new methods of artificial intervention and therapies. This book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.
Cellular Mechanotransduction
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Author : Mohammad R. K. Mofrad
language : en
Publisher:
Release Date : 2010
Cellular Mechanotransduction written by Mohammad R. K. Mofrad and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Cells categories.
'Mechanotransduction' is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.
Cellular Mechanotransduction
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Author : Mohammad R. K. Mofrad
language : en
Publisher:
Release Date : 2009
Cellular Mechanotransduction written by Mohammad R. K. Mofrad and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Cells categories.
Cardiac Mechanotransduction
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Author : Matti Weckström
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-22
Cardiac Mechanotransduction written by Matti Weckström and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-22 with Medical categories.
This book presents a multidisciplinary approach to cardiac mechanotransduction. The chapters depict the many faces of the topic, from membrane and ion channel level to mechanics, biochemical signaling and regulation via hormone systems. Cardiac Mechanotransduction is of interest to basic life sciences, like physiology, biochemistry and pharmacology, but also to clinicians working with heart-related problems, such as cardiologists and internists.
Mechanosensitivity And Mechanotransduction
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Author : Andre Kamkin
language : en
Publisher:
Release Date : 2011-03-30
Mechanosensitivity And Mechanotransduction written by Andre Kamkin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-30 with categories.
Cellular Mechanotransduction Mechanisms In Cardiovascular And Fibrotic Diseases
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-10-22
Cellular Mechanotransduction Mechanisms In Cardiovascular And Fibrotic Diseases written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-22 with Science categories.
Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis, Volume 87, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in "Current Topics in Membranes" series Updated release includes the latest information on Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis
Mechanosensory Transduction In Drosophila Melanogaster
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Author : Xin Liang
language : en
Publisher: Springer
Release Date : 2017-10-11
Mechanosensory Transduction In Drosophila Melanogaster written by Xin Liang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-11 with Medical categories.
This book offers an essential introduction for all graduate students and researchers who are working on or interested in mechanotransduction using fruit flies as their model organisms. Designed for accessibility, it follows a simple five-chapter structure, beginning with a general introduction to mechanotransduction in physiology (Chapter 1) and some basic considerations on the principles behind mechanotransduction processes (Chapter 2). In turn, Chapters 3, 4 and 5 focus on mechanoreceptors in Drosophila melanogaster. Chapter 3 explains how the fly’s mechanosensitive cells (i.e. mechanoreceptors) contribute to its daily life, while Chapter 4 explores the ultrastructural and mechanical basis for the working mechanisms of various fly mechanoreceptors. Lastly, Chapter 5 elaborates on the structure, function and physiology of mechanosensitive molecules in fly mechanoreceptors. Accordingly, the book provides an overall framework, helping readers understand mechanosensory transduction, from the physiological level to the molecular level.