Medicinal Plants For Preventing And Treating Cardiovascular Diseases And The Discovery Of Active Natural Products Advanced Models Novel Paradigms And New Mechanisms
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Medicinal Plants For Preventing And Treating Cardiovascular Diseases And The Discovery Of Active Natural Products Advanced Models Novel Paradigms And New Mechanisms
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Author : Ling Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-16
Medicinal Plants For Preventing And Treating Cardiovascular Diseases And The Discovery Of Active Natural Products Advanced Models Novel Paradigms And New Mechanisms written by Ling Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-16 with Science categories.
Cardioprotective Natural Products Promises And Hopes
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Author : Brahmachari Goutam
language : en
Publisher: World Scientific
Release Date : 2017-10-27
Cardioprotective Natural Products Promises And Hopes written by Brahmachari Goutam and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-27 with Medical categories.
Cardioprotective Natural Products: Promises and Hopes focuses on the recent advances in the research of bioactive natural products with cardioprotective potential against various cardiovascular diseases/disorders. The aim of this book is to underline the promise and future hope in bioactive natural molecules, herbal formulations, natural dietary supplements and related materials in the prevention and cure of cardiovascular diseases in a scientific way. This book, which comprises a variety of about 9 chapters written by active researchers and leading experts, brings together an overview of current discoveries and trends in this field. This volume is also an outstanding source of information with regard to the industrial application of natural products for medicinal purposes. The broad interdisciplinary approach adopted in this book ensures that it is much more interesting to scientists deeply engaged in the research and/or use of bioactive natural products. It will serve not only as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to prevent and treat disease manifestations, but will hopefully also motivate young scientists to engage in the dynamic field of natural products research. Contents: Cardioprotective Natural Products: Promises and Hopes — An Overview (Goutam Brahmachari) Naturally Occurring Matrix Metalloproteinase Inhibitors: A Group of Promising Cardioprotective Agents (Tayebeh Anajafi, Abbas Sedigh and Sanku Mallik ) Promising Natural Cardioprotective Agents in Drug- and Toxin-Induced Pathophysiology (Semantee Bhattacharya and Parames C Sil) Natural Products Against Drug-Induced Cardiotoxicity (Meghana Koneru, Nasiruddin Nalban, Bidya Dhar Sahu and Ramakrishna Sistla ) Cardioprotective Potential of Medicinal Plants in Attenuating Doxorubicin-Induced Cardiotoxicity (Sameer N Goyal, C R Patil, Nimisha Mishra, Rajesh Mohanraj and Shreesh Ojha) The Role of Dietary Supplements in Cardiovascular Diseases (Essam Abdel-Sattar, Soheir M El Zalabani and Manal M Sabry) Beneficial Role of Antioxidant Molecules with Therapeutic Potential in Cardiac Disease (Jyotirmoy Ghosh, Krishnendu Sinha and Parames C Sil) Small Molecule Phytocompounds as Promoters of LDL-Receptor and PCSK9 Inhibition: Potential Role as Non-Statin Based Cardio-Protective Agents (Ajoy Basak, Paul O'Reilly, Bethel Ozed Williams and Sarmistha Basak) 7,8-Dihydroxy-3-methylisochroman-4-one: A Promising Anti-Hypertensive Lead-Molecule from Banana (Musa sapientun L) Peel (Goutam Brahmachari) Readership: Phytochemists; combinatorial chemists; pharmacologists; institutes for drug research (drug discovery and development); industrial research groups developing drugs from medicinal plants; pharmaceutical companies; manufacturers of herbal and ayurvedic medicines and cosmetic products; manufacturers of natural products; advanced and research students. Keywords: Cardioprotective Natural Products;Cardiovascular Diseases and Related Symphtoms;Protection and Therapies;Ayurvedic/Herbal Formulations;Medicinal Compounds of Natural Origins;Therapeutic Targets;Mode of Actions;Pharmacokinetics;Drug Discovery and DevelopmentsReview: Key Features: Contains a variety of 10-12 chapters with written by active researchers and leading experts deeply engaged in the research field with medicinal natural products and herbal formulations Recent cutting-edge advances on medicinal natural products as the preventives and therapies against deadly cardiovascular diseases in a single volume Exhaustive and authoritative presentations of research outcomes on medicinal natural product
Network Pharmacology
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Author : Shao Li
language : en
Publisher: Springer Nature
Release Date : 2021-09-29
Network Pharmacology written by Shao Li and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-29 with Medical categories.
This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Advanced Pharmacological Uses Of Medicinal Plants And Natural Products
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Author : Singh, Ajeet
language : en
Publisher: IGI Global
Release Date : 2020-02-21
Advanced Pharmacological Uses Of Medicinal Plants And Natural Products written by Singh, Ajeet and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-21 with Medical categories.
A vast majority of the world’s population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services. Advanced Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.
Who Global Report On Traditional And Complementary Medicine 2019
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2019-05-16
Who Global Report On Traditional And Complementary Medicine 2019 written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-16 with Business & Economics categories.
This report is structured in five parts: national framework for traditional and complementary medicine (T&CM); product regulation; practices and practitioners; the challenges faced by countries; and finally the country profiles. Apart from the section on practices and practitioners the report is consistent with the format of the report of the first global survey in order to provide a useful comparison. The section on practices and practitioners which covers providers education and health insurance is a new section incorporated to reflect the emerging trends in T&CM and to gather new information regarding these topics at a national level. All new information received has been incorporated into individual country profiles and data graphs. The report captures the three phases of progress made by Member States; that is before and after the first WHO Traditional Medicine Strategy (1999?2005) from the first global survey to the second global survey (2005?2012) and from the second survey to the most recent timeline (2012?2018).
Drug Discovery And Development
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Author : Ramarao Poduri
language : en
Publisher: Springer Nature
Release Date : 2021-02-15
Drug Discovery And Development written by Ramarao Poduri and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-15 with Medical categories.
This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.
Discovery And Development Of Antidiabetic Agents From Natural Products
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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2016-10-11
Discovery And Development Of Antidiabetic Agents From Natural Products written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-11 with Science categories.
Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic. Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications. Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics. Contains chapters written by active researchers and leading global experts who are deeply engaged in the research field of natural product chemistry for drug discovery Provides comprehensive coverage of cutting-edge research advances in the design of medicinal natural products with potential as preventives and therapeutics for diabetes and related metabolic issues Presents a practical review of the identification, isolation, and extraction techniques that help support medicinal chemists in the lab
Drug Discovery And Development
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Author : Omboon Vallisuta
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-06-03
Drug Discovery And Development written by Omboon Vallisuta and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-03 with Medical categories.
It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.
Natural Products
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Author : Lixin Zhang
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-17
Natural Products written by Lixin Zhang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-17 with Medical categories.
A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Innovative Approaches In Drug Discovery
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Author : Bhushan Patwardhan
language : en
Publisher: Academic Press
Release Date : 2016-10-03
Innovative Approaches In Drug Discovery written by Bhushan Patwardhan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-03 with Medical categories.
Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is now for a renewed commitment towards expanding the repertoire of medicines. By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences. Analyzes the reasons behind historical drug failures to provide valuable insights on lessons learned Uses current scientific research to promote learning from traditional knowledge systems and through the integration of traditional and western medicines Discusses advances in technologies and systems biology to support the transition from formulation discovery to therapeutic discovery