Melanins And Melanogenesis
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Melanins And Melanogenesis
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Author : Giuseppe Prota
language : en
Publisher: Academic Press
Release Date : 2012-12-02
Melanins And Melanogenesis written by Giuseppe Prota and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
This volume covers all aspects of melanin pigmentation, providing a concise, comprehensive picture of new knowledge gained at the frontiers of research. It draws heavily on the author's 30-year activity in the field and his continuing work with specialists of widely diverse disciplines. The core of the volume deals with the structure, physicochemical properties, and biosynthesis of the major classes of melanin pigments, including neuromelanins. Further discussions include the biology of the various types of pigment-producing cells, the structure and mode of action of tyrosinase, and the chemistry of urinary melanogens and their biomedical applications as metabolic markers of melanocyte activity, especially for the follow-up of malignant melanoma. Finally, the volume considers progress in the photobiology and photochemistry of melanins, with special emphasis on the controversial role of these pigments in skin photoprotection. Melanins and Melanogenesis is ideally suited as a basic guide for newcomers, and a handy source of specific information for practitioners in academic, medical, and industrial settings.
Melanin Chemistry Explored By Quantum Mechanics
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Author : Ryo Kishida
language : en
Publisher: Springer Nature
Release Date : 2021-04-09
Melanin Chemistry Explored By Quantum Mechanics written by Ryo Kishida and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-09 with Science categories.
This book discusses recent advances in theoretical–computational studies on the biosynthesis of melanin pigment (melanogenesis). These advances are being driven by the development of high-performance computers, new experimental findings, and extensive work on medical applications involving the control of pigmentation and the treatment of challenging dermatological diseases. Understanding the elementary processes involved in chemical reactions at the atomic scale is important in biochemical reaction design for effective control of the pigmentary system. Accordingly, the book focuses on the elementary steps involved in melanogenesis, which crucially affect the composition of the resulting melanin pigment by means of competitive reactions. The book also addresses reactions analogous to melanogenesis, with a focus on o-quinone reactions, which are especially important for understanding melanogenesis-associated cytotoxicity.
Melanins And Melanosomes
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Author : Jan Borovansky
language : en
Publisher: John Wiley & Sons
Release Date : 2011-10-05
Melanins And Melanosomes written by Jan Borovansky and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-05 with Science categories.
The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.
Melanin
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Author : Xiao-Peng Ma
language : en
Publisher: Nova Science Publishers
Release Date : 2014-05-14
Melanin written by Xiao-Peng Ma and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Human skin color categories.
Human melanin is synthesized in melanosomes located in melanocytes of the skin, hair, eyes, and leptomeninges. Melanin not only determines skin color, but also protects the skin from UV damage by absorbing UV light. In this book, the authors present current research in the study of the biosynthesis, functions and health effects of melanin. Topics include melanogenesis and natural hypopigmentation agents; fungal melanins; the coat color genes that regulate eumelanin and pheomelanin synthesis in melanocytes; the role of melanin production in gaeumannomyces graminis infection of cereal plants and the occurrence and function of melanic pigmentation in ectothermic vertebrates.
Melanin Pigmentation Of The Skin
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Author : A. S. Breathnach
language : en
Publisher:
Release Date : 1971
Melanin Pigmentation Of The Skin written by A. S. Breathnach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medical categories.
Melanins Functions Biotechnological Production And Applications
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Author : Guillermo Gosset
language : en
Publisher: Springer Nature
Release Date : 2023-05-30
Melanins Functions Biotechnological Production And Applications written by Guillermo Gosset and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-30 with Science categories.
This book provides an up-to-date overview of the biological functions of melanins, their biotechnological production, and their industrial applications. The melanins form a group of polymeric pigments found in most organisms. These natural products are generated by the oxidation of phenolic and indolic molecules yielding melanins, which include eumelanin, pheomelanin, pyomelanin, and the allomelanins. These pigments have diverse biological functions, including photoprotection, thermoregulation, antioxidation, virulence, and metal ion sequestration. Melanins have physicochemical properties that have proven useful in the optical, electronic, material, agriculture, cosmetic, pharmaceutical, and medical industries. The chapters in this book provide an in-depth analysis of the current issues and challenges in this field. Topics covered include the properties, biogenesis, and evolution of melanosomes. The book also addresses the synthesis and industrial production of melanins by microorganisms. The metabolic pathways for the synthesis of several types of polymeric pigments in microorganisms and their role in pathogenesis are reviewed. The large-scale production and purification of melanins to provide this product for industrial applications is a formidable challenge. Two chapters present and discuss the state-of-the-art used for the generation of microbial melanin-production strains and the processes for the biotechnological synthesis and purification of these pigments. Melanins are polymers that can interact with metals, a chapter reviews this capacity in the context of technological applications, including electrochemical energy storage and metal recovery. These polymers are materials having favorable characteristics for photonic applications, including UV blocking and broadband absorption. The current advances in the application of these pigments in optically active materials are presented and discussed.
Melanin
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Author : Miroslav Blumenberg
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-03-01
Melanin written by Miroslav Blumenberg and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-01 with Science categories.
The word melanin refers to dark natural pigments produced by the oxidative degradation of tyrosine, catalyzed by tyrosinase, and polymerized into insoluble granular substance. The main function of melanin is to protect from harmful agents, primarily UV radiation, but also from oxidation, heavy metals, etc. In this volume, chapters deal with production of melanin in human oral mucosa (Liviu et al.), the regulation of melanin action (Cecile et al.), production and potential technological application of fungal melanins (Pombiero-Sponchiado et al.) and an innovative method for measuring melanin in various samples (Zdybel et al.). In conclusion, this volume presents various biological and industrial aspects of melanin production, uses and analysis.
The Pigmentary System
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Author : James J. Nordlund
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
The Pigmentary System written by James J. Nordlund and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.
The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.
Analysis Of Melanins
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Author : Gerd Odh Olsson
language : en
Publisher:
Release Date : 1998
Analysis Of Melanins written by Gerd Odh Olsson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Melanins categories.
Vitiligo
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Author : Somesh Gupta
language : en
Publisher: John Wiley & Sons
Release Date : 2018-04-30
Vitiligo written by Somesh Gupta and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-30 with Medical categories.
Practical guidance based on expert experience and evidence for developing management strategies for vitiligo This complete guide to vitiligo provides a full appraisal of strategy for the treatment of this autoimmune disease that affects 1-2% of the world’s population. It addresses all aspects of vitiligo, covering the science, medical and surgical therapies, and the psychological evaluations and approaches based on the proper understanding of the causes and classification of a particular case. Management of vitiligo is challenging and requires a multipronged approach. Vitiligo: Medical and Surgical Management is a comprehensive, timely, state-of-the-art resource that will help those involved with affected patients better understand and treat this disease, which takes its toll on the mental wellness of those afflicted by it. It takes an evidenced-based approach to the disease’s treatment; provides an overview of the surgical management; covers tissue and cellular grafting; and more. Thoroughly guides those involved in the clinical aspects of vitiligo Aids diagnosis and classification of severity Balances evidence and experience Compiled by world-leading expert editors Comprehensive in nature, Vitiligo: Medical and Surgical Management contains a strong practical element, and is a welcome go-to source for practicing dermatologists and those training to become a dermatologist.