Membrane Trafficking Pathways And Protein Sorting In The Yeast Saccharomyces Cerevisiae

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Membrane Trafficking Pathways And Protein Sorting In The Yeast Saccharomyces Cerevisiae

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Author : Edina Harsay
language : en
Publisher:
Release Date : 1996

Membrane Trafficking Pathways And Protein Sorting In The Yeast Saccharomyces Cerevisiae written by Edina Harsay and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.

Protein Lipid And Membrane Traffic

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Author : North Atlantic Treaty Organization. Scientific Affairs Division
language : en
Publisher: IOS Press
Release Date : 2000

Protein Lipid And Membrane Traffic written by North Atlantic Treaty Organization. Scientific Affairs Division and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Biological transport categories.

This text concentrates on the following specific topics: the dynamic character of lipids and proteins in biological membranes; the existence of specific domains in membranes including their visualisation; the molecular mechanisms of intracellular transport of membrane constituents and the involvement of lipid-protein interactions in these processes; protein assembly; structure and folding and transport through membranes; and the intracellular sorting and targeting of individual membrane components as well as different organelles."

Membrane Protein Sorting In The Secretory Pathway Of Saccharomyces Cerevisiae

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Author : Christopher John Roberts
language : en
Publisher:
Release Date : 1991

Membrane Protein Sorting In The Secretory Pathway Of Saccharomyces Cerevisiae written by Christopher John Roberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Cell physiology categories.

Characterization Of Saccharomyces Cerevisiae Trans Golgi Network Protein Trafficking Events Using Cell Free Systems

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Author : Jennifer M. Blanchette
language : en
Publisher:
Release Date : 2004

Characterization Of Saccharomyces Cerevisiae Trans Golgi Network Protein Trafficking Events Using Cell Free Systems written by Jennifer M. Blanchette and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.

Characterization Of Vacuolar Membrane Protein Transport In Saccharomyces Cerevisiae

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Author : Christopher Rollefson Cowles
language : en
Publisher:
Release Date : 1998

Characterization Of Vacuolar Membrane Protein Transport In Saccharomyces Cerevisiae written by Christopher Rollefson Cowles and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.

Molecular Mechanisms For Protein Transport And Regulation Of Membrane Fusion In The Vacuolar Protein Sorting Pathway

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Author : Tamara Darsow
language : en
Publisher:
Release Date : 2000

Molecular Mechanisms For Protein Transport And Regulation Of Membrane Fusion In The Vacuolar Protein Sorting Pathway written by Tamara Darsow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.

Molecular Requirements For Protein Transport To The Endosome And Vacuole In Saccharomyces Cerevisiae

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Author : Stephanie E. Rieder
language : en
Publisher:
Release Date : 1998

Molecular Requirements For Protein Transport To The Endosome And Vacuole In Saccharomyces Cerevisiae written by Stephanie E. Rieder and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.

A Study Of Vacuolar Kinase Env7 Trafficking In Saccharomyces Cerevisiae

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Author : Leah Frisardi
language : en
Publisher:
Release Date : 2019

A Study Of Vacuolar Kinase Env7 Trafficking In Saccharomyces Cerevisiae written by Leah Frisardi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Autophagic vacuoles categories.

Abstract: The vacuole in Saccharomyces cerevisiae (baker’s yeast) is functionally analogous to the human lysosome. Endosome and vacuolar interface 7 (Env7) has been recently identified in the Gharakhanian laboratory as a protein kinase that regulates vacuolar fusion and has a human ortholog, STK16. Previous research in our laboratory has shown that Env7 localizes to the vacuolar membrane in yeast. Proteins destined to function at the yeast vacuole are transported from the Golgi via two distinct pathways: the carboxypeptidase Y (CPY) pathway and the alkaline phosphatase (ALP) pathway. The CPY pathway requires an endosomal intermediate while the ALP pathway requires an adaptor protein complex (AP-3). The CPY pathway serves as the default pathway for the vast majority of proteins moving from the Golgi to the vacuole. Only 9 proteins are known to be transported via the ALP pathway in yeast, all of which are vacuolar membrane proteins and one of which is Yck3, a palmitoylated protein kinase with a similar function of Env7. Proteins normally transported to the yeast vacuole via the ALP pathway are able to partially revert to the CPY pathway when AP-3 function is disrupted. In the absence of a functional CPY pathway, however, the AP-3 pathway remains cargo-specific. Here we show that when the CPY pathway is disrupted in yeast cells, Env7 shows a significant increase in mislocalization. When the ALP pathway is disrupted, Env7 shows no significant mislocalization. Proteins transported via the ALP pathway interact with AP-3 via either an acidic-dileucine-like or a tyrosine-based adaptin sorting signal. Analysis of the amino acid sequence of Env7 showed one potential acidic-dileucine like signal and four potential tyrosine-based adaptin sorting signals. Mutagenesis of two of these sorting signals caused no significant mislocalization of Env7 in yeast. These results implicate the CPY pathway in the vacuolar trafficking of Env7 in yeast.

Trafficking Inside Cells

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Author : Nava Segev
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-30

Trafficking Inside Cells written by Nava Segev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-30 with Science categories.

This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

Determinants For Protein Sorting At The Trans Golgi Network And Secretory Pathways

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Author : Ewelina Biskup
language : en
Publisher:
Release Date : 2008

Determinants For Protein Sorting At The Trans Golgi Network And Secretory Pathways written by Ewelina Biskup and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.