Membrane Transport Of Antineoplastic Agents


Membrane Transport Of Antineoplastic Agents
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Membrane Transport Of Antineoplastic Agents


Membrane Transport Of Antineoplastic Agents
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Author : I. David Goldman
language : en
Publisher: Pergamon
Release Date : 1986

Membrane Transport Of Antineoplastic Agents written by I. David Goldman and has been published by Pergamon this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.


Hardbound. This volume comprehensively covers the membrane dynamics of anticancer drug action. Each chapter deals with specific drugs and discusses the pharmacokinetics of the drug at all major sites of activity. By dealing with the dynamics of the drugs at the membrane level the fundamental aspects of drug action are considered in all organs that are important to the clinical oncologist. The accumulation of this knowledge in a single volume will be a great advance in the chemotherapy of cancer, and an excellent manual for students, trainees and researchers who wish to study this phenomenon.



Metallo Drugs Development And Action Of Anticancer Agents


Metallo Drugs Development And Action Of Anticancer Agents
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Author : Astrid Sigel
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2018-02-05

Metallo Drugs Development And Action Of Anticancer Agents written by Astrid Sigel and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-05 with Science categories.


Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching.



Holland Frei Cancer Medicine


Holland Frei Cancer Medicine
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Author : Robert C. Bast, Jr.
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-10

Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-10 with Medical categories.


Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates



Antimalarial Chemotherapy


Antimalarial Chemotherapy
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Author : Philip J. Rosenthal
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-04-01

Antimalarial Chemotherapy written by Philip J. Rosenthal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-04-01 with Medical categories.


Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery clearly delineates all the basic and clinical research now addressing one of the world's major unresolved disease problems, work that is now powerfully driving the rapid pace of antimalarial drug discovery today.



Cancer Treatment Reports


Cancer Treatment Reports
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Author :
language : en
Publisher:
Release Date : 1981

Cancer Treatment Reports written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Cancer categories.




Research Grants Index


Research Grants Index
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Author : National Institutes of Health (U.S.). Division of Research Grants
language : en
Publisher:
Release Date : 1975

Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Medicine categories.




Subject Index Of Extramural Research Administered By The National Cancer Institute


Subject Index Of Extramural Research Administered By The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 1979

Subject Index Of Extramural Research Administered By The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Cancer categories.


Current information about research grants and contracts supported by the National Cancer Institute. Subject listing gives contract or grant number and topic. Investigator, grant number, and contract number indexes.



Subject Index Of Current Extramural Research Administered By The National Cancer Institute


Subject Index Of Current Extramural Research Administered By The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 1978

Subject Index Of Current Extramural Research Administered By The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Cancer categories.




Current Research On Pre Clinical Aspects Of Cancer Therapy


Current Research On Pre Clinical Aspects Of Cancer Therapy
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Author : Current Cancer Research Project Analysis Center (U.S.)
language : en
Publisher:
Release Date : 1975

Current Research On Pre Clinical Aspects Of Cancer Therapy written by Current Cancer Research Project Analysis Center (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Cancer categories.


1038 references to research projects being conducted in the United States and elsewhere. Entries arranged under 5 topics, e.g., Preclinical studies of anticancer drugs, Preclinical radiation therapy, and Preclinical immunotherapy. Entriesinclude title, researcher, address, contract number, summary, and supporting agency. Indexes by subjects, investigators, contractors, supporting agencies, and contractor numbers.



National Library Of Medicine Current Catalog


National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date :

National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medicine categories.