Membrane Transporters In The Pathogenesis Of Cardiovascular And Lung Disorders
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Membrane Transporters In The Pathogenesis Of Cardiovascular And Lung Disorders
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-06-05
Membrane Transporters In The Pathogenesis Of Cardiovascular And Lung Disorders written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-05 with Science categories.
Membrane Transporters in the Pathogenesis of Cardiovascular and Lung Disorders, Volume 83, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this volume presenting chapters from recognized experts on topics such as cardiotonic steroids, Na+, K+ pumps and vascular fibrosis, purinergic signaling in the lung, structural models of a2-subunit N-termini and binding interfaces, ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients, the Na, K-ATPase alpha2 isoform in cardiovascular pathologies, the role of cell swelling and volume-sensitive ion channels in stroke pathology, structure-function relationships in the renal NaCl cotransporter, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Membranes series Includes the latest information on membrane ion transporters
How Tobacco Smoke Causes Disease
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Author :
language : en
Publisher:
Release Date : 2010
How Tobacco Smoke Causes Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Government publications categories.
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Research Awards Index
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Author :
language : en
Publisher:
Release Date : 1989
Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.
Subject Index Of Current Research Grants And Contracts Administered By The National Heart Lung And Blood Institute
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Author : National Heart, Lung, and Blood Institute
language : en
Publisher:
Release Date : 1975
Subject Index Of Current Research Grants And Contracts Administered By The National Heart Lung And Blood Institute written by National Heart, Lung, and Blood Institute and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Cardiovascular system categories.
Research Grants Index
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Author : National Institutes of Health (U.S.). Division of Research Grants
language : en
Publisher:
Release Date : 1975
Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Medicine categories.
Biomedical Index To Phs Supported Research
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Author :
language : en
Publisher:
Release Date : 1989
Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.
Physiology And Pathology Of Chloride Transporters And Channels In The Nervous System
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Author : F. Javier Alvarez-Leefmans
language : en
Publisher: Academic Press
Release Date : 2009-08-22
Physiology And Pathology Of Chloride Transporters And Channels In The Nervous System written by F. Javier Alvarez-Leefmans and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-22 with Medical categories.
The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the growth of molecular biology and the advent of new optical methods, an enormous amount of exciting new information has become available on the molecular structure and function of Cl- channels and carriers. In nerve cells, Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control. Disruption of Cl- homeostasis in neurons underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases. The first comprehensive book on the structure, molecular biology, cell physiology, and role in diseases of chloride transporters / channels in the nervous system in almost 20 years Chloride is the most abundant free anion in animal cells. THis book summarizes and integrates for the first time the important research of the past two decades that has shown that Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control The first book that systematically discusses the result of disruption of Cl- homeostasis in neurons which underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation Spanning topics from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases Involves all of the leading researchers in the field Includes an extensive introductory section that covers basic thermodynamic and kinetics aspects of Cl- transport, as well as current methods for studying Cl- regulation, spanning from fluorescent dyes in single cells to knock-out models to make the book available for a growing population of graduate students and postdocs entering the field
Subject Index Of Current Research Grants And Contracts Administered By The National Heart And Lung Institute
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Author : National Heart and Lung Institute
language : en
Publisher:
Release Date : 1975
Subject Index Of Current Research Grants And Contracts Administered By The National Heart And Lung Institute written by National Heart and Lung Institute and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Cardiology categories.
Pathophysiology E Book
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Author : Jacquelyn L. Banasik
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-12-21
Pathophysiology E Book written by Jacquelyn L. Banasik and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-21 with Medical categories.
A clear, comprehensive introduction to disease, Pathophysiology, 5th Edition explores the etiology, pathogenesis, clinical manifestations, and treatment of disorders. Units are organized by body system, and each begins with an illustrated review of anatomy and normal physiology. A discussion then follows on the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by leading educators Lee-Ellen Copstead and Jacquelyn Banasik, Pathophysiology simplifies a rigorous subject with practical learning resources and includes coverage of the latest scientific findings and relevant research 900 full-color illustrations clarify complex pathophysiological concepts. Easy-to-read style includes many tables, boxes, and figures to highlight and simplify content. Key Questions at the beginning of each chapter highlight key objectives and help you develop and use critical thinking skills. Key Points boxes focus on the most important information. Geriatric Considerations boxes analyze the age-related changes associated with a specific body system. A chapter summary gives you a quick wrap-up of the key content in each chapter. NEW! Pediatric Considerations boxes with accompanying flow charts describe conditions and changes specific to young children. NEW! Updated content includes the latest information on new treatment advances, the relationship between stress and inflammation to cardiovascular disease, and much more throughout the text. NEW! Global Health Considerations tables include information on HIV/AIDS and depression/anxiety in women.
Textbook Of Membrane Biology
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Author : Rashmi Wardhan
language : en
Publisher: Springer
Release Date : 2018-01-10
Textbook Of Membrane Biology written by Rashmi Wardhan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-10 with Science categories.
This book provides a comprehensive overview of the basic principles, concepts, techniques and latest advances in the field of biomembranes and membrane-associated processes. With new emerging technologies and bioinformatics tools, this is a promising area for future study and research. The book discusses the composition, fluidity and dynamic nature of phospholipid bilayers, which vary with cell/organelle type and function. It describes the various types of transport proteins that facilitate the transport of polar and nonpolar molecules across the membrane actively or passively via ion-channels or through porins. It also explores the many cellular functions membranes participate in: (1) energy transduction, which includes the electron transport chain in inner membrane of mitochondria and bacterial cytoplasmic membrane and photosynthetic electron transport in thylakoid membranes in chloroplast and photosynthetic bacterial membranes; (2) cell–cell communication involving various signal transduction pathways triggered by activated membrane receptors; (3) cell–cell interactions involving various types of adhesion and receptor proteins; (4) nerve transmission involving opening and closing of voltage gated ionic channels; and (5) intracellular transport involving the processes of endocytosis, exocytosis, vesicular transport of solutes between intracellular compartments, membrane fusion and membrane biogenesis.