Membranes To Molecular Machines
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Membranes To Molecular Machines
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Author : Mathias Grote
language : en
Publisher: University of Chicago Press
Release Date : 2019-07-09
Membranes To Molecular Machines written by Mathias Grote and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-09 with Science categories.
Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" open and close in our brain cell membranes; when we run, tiny "motors" spin in our muscle cell membranes; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing “proton pump inhibitors” or medicines similar to Prozac. Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences not only have made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as "active matter" in new ways. Covering the science of biological membranes in the United States and Europe from the mid-1960s to the 1990s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and will enlighten and provoke anyone interested in the intersection of chemical research and the life sciences—from practitioner to historian to philosopher.
Molecular Machines Involved In Protein Transport Across Cellular Membranes
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Author :
language : en
Publisher:
Release Date : 2007
Molecular Machines Involved In Protein Transport Across Cellular Membranes written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Cell proliferation categories.
The Enzymes
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Author : Ross Dalbey
language : en
Publisher: Elsevier
Release Date : 2007-08-28
The Enzymes written by Ross Dalbey and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-28 with Science categories.
This volume of The Enzymes features high-caliber thematic articles on the topic of molecular machines involved in protein transport across cellular membranes. The book consists of five parts which span the range of membranes including bacterial, endoplasmic reticulum, mitochondrial, chloroplast, and peroxismal.
Molecular Machines
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Author : Anthony Gordon Lee
language : en
Publisher:
Release Date : 1996
Molecular Machines written by Anthony Gordon Lee and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Biochemistry categories.
Cell Biology By The Numbers
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Author : Ron Milo
language : en
Publisher: Garland Science
Release Date : 2015-12-07
Cell Biology By The Numbers written by Ron Milo and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-07 with Science categories.
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Molecular Machines
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Author : Benoît Roux
language : en
Publisher: World Scientific
Release Date : 2011
Molecular Machines written by Benoît Roux and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
Ch. 1. Molecular behavior in biological cells : the bacterial cytoplasm as a model system / Adrian H. Elcock and Andrew S. Thomas -- ch. 2. The light-harvesting apparatus in purple photosynthetic bacteria : introduction to a quantum biological device / Johan Strumpfer [und weitere] -- ch. 3. DNA polymerases : structure, function, and modeling / Tamar Schlick -- ch. 4. Information processing by nanomachines : decoding by the ribosome / Karissa Y. Sanbonmatsu, Scott C. Blanchard and Paul C. Whitford -- ch. 5. Chaperonins : the machines which fold proteins / Del Lucent, Martin C Stumpe and Vijay S Pande -- ch. 6. Muscle and myosin / Ronald S. Rock -- ch. 7. Protein kinases : phosphorylation machines / Elaine E. Thompson, Susan S. Taylor and J. Andrew McCammon -- ch. 8. Computational studies of Na+/H+ antiporter : structure, dynamics and function / Assaf Ganoth, Raphael Alhadeff and Isaiah T. Arkin -- ch. 9. Membrane transporters : molecular machines coupling cellular energy to vectorial transport across the membrane / Zhijian Huang [und weitere] -- ch. 10. ABC transporters / E.P. Coll and D.P. Tieleman -- ch. 11. Sodium-coupled secondary transporters : insights from structure-based computations / Elia Zomot [und weitere] -- ch. 12. Voltage-gated ion channels : the machines responsible for the nerve impulse / Benoit Roux and Francisco Bezanilla -- ch. 13. Voltage-gated channels and the heart / Jonathan R. Silva and Yoram Rudy
Life S Ratchet
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Author : Peter M Hoffmann
language : en
Publisher: Hachette UK
Release Date : 2012-10-30
Life S Ratchet written by Peter M Hoffmann and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-30 with Science categories.
Life is an enduring mystery. Yet, science tells us that living beings are merely sophisticated structures of lifeless molecules. If this view is correct, where do the seemingly purposeful motions of cells and organisms originate? In Life's Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale. Below the calm, ordered exterior of a living organism lies microscopic chaos, or what Hoffmann calls the molecular storm -- specialized molecules immersed in a whirlwind of colliding water molecules. Our cells are filled with molecular machines, which, like tiny ratchets, transform random motion into ordered activity, and create the "purpose" that is the hallmark of life. Tiny electrical motors turn electrical voltage into motion, nanoscale factories custom-build other molecular machines, and mechanical machines twist, untwist, separate and package strands of DNA. The cell is like a city -- an unfathomable, complex collection of molecular workers working together to create something greater than themselves. Life, Hoffman argues, emerges from the random motions of atoms filtered through these sophisticated structures of our evolved machinery. We are agglomerations of interacting nanoscale machines more amazing than anything in science fiction. Rather than relying on some mysterious "life force" to drive them -- as people believed for centuries -- life's ratchets harness instead the second law of thermodynamics and the disorder of the molecular storm. Grounded in Hoffmann's own cutting-edge research, Life's Ratchet reveals the incredible findings of modern nanotechnology to tell the story of how the noisy world of atoms gives rise to life itself.
The Machinery Of Life
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Author : David S. Goodsell
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
The Machinery Of Life written by David S. Goodsell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
A journey into the sub-microscopic world of molecular machines. Readers are first introduced to the types of molecules built by cells: proteins, nucleic acids, lipids, and polysaccharides. Then, in a series of distinctive illustrations, the reader is guided through the interior world of cells, exploring the ways in which molecules work in concert to perform the processes of living. Finally, the author shows us how vitamins, viruses, poisons, and drugs each have their effects on the molecules in our bodies. David Goodsell, author and illustrator, has prepared a fascinating introduction to biochemistry for the non-specialist. His book combines a lucid text with an abundance of drawings and computer graphics that present the world of cells and their components in a truly unique way.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Mechanism Of Functional Expression Of The Molecular Machines
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Author : Masahiro Kinoshita
language : en
Publisher: Springer
Release Date : 2016-06-14
Mechanism Of Functional Expression Of The Molecular Machines written by Masahiro Kinoshita and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-14 with Science categories.
This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system.