Metabolic Basis Of Obesity
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Metabolic Basis Of Obesity
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Author : Rexford S. Ahima
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-16
Metabolic Basis Of Obesity written by Rexford S. Ahima and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-16 with Medical categories.
The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.
Metabolic Basis Of Obesity
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Author : Rexford S. Ahima
language : en
Publisher: Springer
Release Date : 2010-11-17
Metabolic Basis Of Obesity written by Rexford S. Ahima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-17 with Medical categories.
The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.
Obesity And Metabolism
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Author : Márta Korbonits
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2008-01-01
Obesity And Metabolism written by Márta Korbonits and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-01 with Medical categories.
It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.
Overweight And The Metabolic Syndrome
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Author : George A. Bray
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-16
Overweight And The Metabolic Syndrome written by George A. Bray and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-16 with Medical categories.
This timely book provides an overview of topics related to obesity. These include associated health risks, childhood obesity, genetics, evaluation, treatment, behavioral strategies, and successes and failures in preventing obesity. The volume covers evaluation guidelines, different approaches to treatment, including diet, exercise, behavior, drugs, and surgery to deal with the current world-wide obesity epidemic.
Cellular And Biochemical Mechanisms Of Obesity
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Author : Paramjit S. Tappia
language : en
Publisher: Springer Nature
Release Date : 2021-12-15
Cellular And Biochemical Mechanisms Of Obesity written by Paramjit S. Tappia and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-15 with Medical categories.
Global health has been challenged with the dawning of the era of the obesity epidemic, and thus as a consequence, strategies to reduce obesity have become public health priorities. According to the United Nations, obesity has been identified as a concern for achieving Sustainable Development Goals. Obesity is a serious health problem with an increased risk of several common diseases including diabetes, cardiovascular disease, and cancer. Although the fundamental cause of obesity and overweight is an imbalance between calorie intake and calorie expenditure, the underlying biochemical and metabolic processes that cause obesity are not fully understood. Two earlier volumes dedicated to the subject of obesity, published in the series “Advances in Biochemistry in Health and Disease” focused on the pathophysiology of obesity-induced health complications and the biochemistry of cardiovascular dysfunction in obesity. This book brings together contributions from international experts in the field to describe advancements on the mechanisms leading to development of obesity and related complications. There are 21 chapters in two different parts in this book, comprising of Part I: Pathophysiologic Mechanisms of Obesity (11 chapters) and Part II: Therapeutic Mechanisms of Obesity (10 chapters). This book will serve as a resource and be of interest to health professionals, medical students, fellows, residents and graduate students. It will also evoke innovative research and effective approaches for the prevention of obesity. This volume will accentuate that obesity is a major health hazard in its own right and that appropriate public health measures should be implemented to prevent or reduce or even reverse the impact of this global chronic disease.
The Genetics Of Obesity
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Author : Claude Bouchard
language : en
Publisher: CRC Press
Release Date : 2020-08-11
The Genetics Of Obesity written by Claude Bouchard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-11 with Medical categories.
This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.
Sensory And Metabolic Control Of Energy Balance
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Author : Wolfgang Meyerhof
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-24
Sensory And Metabolic Control Of Energy Balance written by Wolfgang Meyerhof and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-24 with Science categories.
During the last two decades, the prevalence of obesity has dramatically increased in western and westernized societies. Its devastating health consequences include hypertension, cardiovascular diseases, or diabetes and make obesity the second leading cause of unnecessary deaths in the USA. As a consequence, obesity has a strong negative impact on the public health care systems. Recently emerging scienti?c insight has helped understanding obesity as a complex chronic disease with multiple causes. A multileveled gene–environment interaction appears to involve a substantial number of susceptibility genes, as well as associations with low physical activity levels and intake of high-calorie, low-cost, foods. Unfor- nately, therapeutic options to prevent or cure this disease are extremely limited, posing an extraordinary challenge for today’s biomedical research community. Obesity results from imbalanced energy metabolism leading to lipid storage. Only detailed understanding of the multiple molecular underpinnings of energy metabolism can provide the basis for future therapeutic options. Numerous aspects of obesity are currently studied, including the essential role of neural and endocrine control circuits, adaptive responses of catabolic and anabolic pathways, metabolic fuel sensors, regulation of appetite and satiation, sensory information processing, transcriptional control of metabolic processes, and the endocrine role of adipose tissue. These studies are predominantly fuelled by basic research on mammalian models or clinical studies, but these ?ndings were paralleled by important insights, which have emerged from studying invertebrate models.
Metabolic Syndrome And Obesity In Childhood And Adolescence
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Author : W. Kiess
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2015-01-27
Metabolic Syndrome And Obesity In Childhood And Adolescence written by W. Kiess and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-27 with Medical categories.
Despite the fact that the prevalence of obesity in early childhood has been stable and is no longer increasing in many developed and industrialized countries, the incidence of both obesity and full-blown metabolic syndrome in children and adolescents is still very high. Obesity is a major disease burden in all societies and needs to be prevented early in life. New approaches are eagerly sought and absolutely necessary. This book presents a comprehensive and state-of-the-art summary of current and new knowledge in this critical field. Crucial issues such as nutrition and genetics are described in detail. In addition, new ideas such as e-health and the consequences of urban living conditions are explored. Last but not least, modern treatment concepts and prevention even at an early age are competently discussed. Offering a valuable update on new developments in obesity research and the treatment in children and adolescents, this book is essential reading for all pediatricians and health-care professionals who look after young patients on a regular basis.
The Metabolic Syndrome And Obesity
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Author : George A. Bray
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-01-23
The Metabolic Syndrome And Obesity written by George A. Bray and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-23 with Science categories.
This book presents an up-to-date survey of the current scientific understanding of obesity and the metabolic syndrome, as well as an overview of the most significant changes to the field over the past 30 years. The book defines obesity and realistically assesses its prevalence. It further examines and evaluates the success of traditional cognitive behavioral treatment. This volume is a thorough reference for obesity and the metabolic syndrome.
Obesity And Energy Metabolism
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Author : National Institutes of Health (U.S.)
language : en
Publisher:
Release Date : 1979
Obesity And Energy Metabolism written by National Institutes of Health (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Energy metabolism categories.
Abstract: A comprehensive yet uncomplicated discussion of obesity is presented for the average adult as part of a series called "Medicine for the Layman." Although the specific causes of obesity are unknown, many factors, such as genetics and environment, influence the condition. More is known about the health consequences of obesity in terms of increased risk of diabetes, cardiovascular diseases and emotional stress. Obesity is defined; the functions of the human body which help determine the numbers and size of fat cells in adipose tissue (hypertrophic and hyperplastic obesity) are described. The balance of caloric intake and energy expenditure for each individual is emphasized. Further research needs are identified. The information is reinforced by a question and answer section and color cartoons.